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Protein Overview: pde-4

General Information:
Name(s) found: pde-4 / CE33439 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00020114 locus:pde-4 Probable 3',5'-cyclic phosphodiesterase pde-4 status:Confirmed UniProt:Q22000 protein_id:CCD69648.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 612 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: signal transduction [IEALink to PubMed article]
    Molecular Function: catalytic activity [IEALink to PubMed article]
    3',5'-cyclic-nucleotide phosphodiesterase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGVARRKQF KLRPWQSTAL PSRHDHYSCA GSATAADGLG GAHLTPSLSS SVHARRESFL  60
   61 YRASDDLREA SSLRPVSRAS SIASNEHGHG DDLIVTPFAQ LLASLRNVRS NLISITNIQN 120
  121 SDDSRHANRS AKRPPLHNIE LPDDVVHCAH DTLEELDWCL DQLETIQTHR SVSEMASSKF 180
  181 RKMLNKELSH FAESSKSGTQ VSKFLITTYM DKEEDEPSIE IEVPTEVQGP STSGPMTLSI 240
  241 LKKAQTAAMN KISGVRKLRA PSHDGHVPEY GVNCAREIAV HMQRLDDWGP DVFKIDELSK 300
  301 NHSLTVVTFS LLRQRNLFKT FEIHQSTLVT YLLNLEHHYR NNHYHNFIHA ADVAQSMHVL 360
  361 LMSPVLTEVF TDLEVLAAIF AGAVHDVDHP GFTNQYLINS NNELAIMYND ESVLEQHHLA 420
  421 VAFKLLQDSN CDFLANLSRK QRLQFRKIVI DMVLATDMSK HMSLLADLKT MVEAKKVAGN 480
  481 NVIVLDKYND KIQVLQSMIH LADLSNPTKP IELYQQWNQR IMEEYWRQGD KEKELGLEIS 540
  541 PMCDRGNVTI EKSQVGFIDY IVHPLYETWA DLVYPDAQNI LDQLEENREW YQSRIPEEPD 600
  601 TARTVTEDDE HK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..134] MSA 5.068979 View MSA. No confident structure predictions are available.
    2 View Details [135..263] deduced N/A No confident structure predictions are available.
    3 View Details [264..612] PSI-BLAST 126.0 Catalytic domain of cyclic nucleotide phosphodiesterase pde4d

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • cyclic-nucleotide phosphodiesterase activity
    		•  2.9145758096876 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle