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Protein Overview: frs-1

General Information:
Name(s) found: frs-1 / CE33173 [WormBase]
Description(s) found:
Found 16 descriptions.
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  • WBGene00001497 locus:fars-1 status:Confirmed UniProt:Q86B36 protein_id:CCD67615.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 496 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: tRNA aminoacylation for protein translation [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    phenylalanyl-tRNA aminoacylation [IEALink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed article]
    translation [IEALink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    aminoacyl-tRNA ligase activity [IEALink to PubMed article]
    phenylalanine-tRNA ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAETDVRST ENLPQQILDF LQESNEFNSI QLAQQWNLDH QKVIGAIKSL LANEGVLTTK  60
   61 DVTEKRLELT NEGVQFANEG SPEYLVFEFV GTDGAAQADI QKKPFGKIGM AKAMQFKWVS 120
  121 VDKGRVVRQA TEVTDSTRKQ LESLRIGSSD VSENEKKELK KRKLISEVNI KALVVSKGTS 180
  181 FTTSLAKQEA DLTPEMIASG SWKDMQFKKY NFDSLGVVPS SGHLHPLMKV RSEFRQIFFS 240
  241 MGFSEMATNR YVESSFWNFD ALFQPQQHPA RDAHDTFFVS DPAISTKFPE DYLERVKTVH 300
  301 SKGGYGSAGY NYDWKIEEAQ KNVLRTHTTA VSARQLYQLA QEGFRPSKLF SIDRVFRNET 360
  361 LDATHLAEFH QVEGVIAEKN LSLAHLIGIF TEFFKKLGIT NLRFKPTYNP YTEPSMEIFA 420
  421 YHQGLTKWVE IGNSGMFRPE MLLPMGLPAD VNVAGYGLSL ERPTMIKYGI NNIRDLFGSK 480
  481 IDLNVVYNNP ICRLDK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..113] FFAS03 1.15 No description for 2gqqA was found.
    2 View Details [114..496] PSI-BLAST 74.09691 Phenyl-tRNA synthetase (PheRS) alpha subunit, PheS

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • phenylalanine-tRNA ligase activity
    		•  13.8919118344182 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  12.5698315343202 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  12.5698315343202 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  12.5592545638101 bayes_pls_golite062009
  • ligase activity
    		•  6.92073480193262 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  2.61548498770105 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  2.18642354927 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  2.07594942154162 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  1.82594054955281 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  1.72324031407565 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  1.72215103383322 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  0.921492123574877 bayes_pls_golite062009
  • binding
    		•  0.705666054154871 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.00572514744734753 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle