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View Structure Prediction Details

Protein: frs-1
Organism: Caenorhabditis elegans
Length: 496 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for frs-1.

Description E-value Query
Range
Subject
Range
frs-1 - phenylalanyl-tRNA synthetase status:Confirmed UniProt:Q9GYS8 protein_id:AAG00015.1
461.0 [0..1] [496..57]

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Predicted Domain #1
Region A:
Residues: [1-113]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAETDVRST ENLPQQILDF LQESNEFNSI QLAQQWNLDH QKVIGAIKSL LANEGVLTTK  60
   61 DVTEKRLELT NEGVQFANEG SPEYLVFEFV GTDGAAQADI QKKPFGKIGM AKA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.15
Match: 2gqqA
Description: No description for 2gqqA was found.

Predicted Domain #2
Region A:
Residues: [114-496]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQFKWVSVDK GRVVRQATEV TDSTRKQLES LRIGSSDVSE NEKKELKKRK LISEVNIKAL  60
   61 VVSKGTSFTT SLAKQEADLT PEMIASGSWK DMQFKKYNFD SLGVVPSSGH LHPLMKVRSE 120
  121 FRQIFFSMGF SEMATNRYVE SSFWNFDALF QPQQHPARDA HDTFFVSDPA ISTKFPEDYL 180
  181 ERVKTVHSKG GYGSAGYNYD WKIEEAQKNV LRTHTTAVSA RQLYQLAQEG FRPSKLFSID 240
  241 RVFRNETLDA THLAEFHQVE GVIAEKNLSL AHLIGIFTEF FKKLGITNLR FKPTYNPYTE 300
  301 PSMEIFAYHQ GLTKWVEIGN SGMFRPEMLL PMGLPADVNV AGYGLSLERP TMIKYGINNI 360
  361 RDLFGSKIDL NVVYNNPICR LDK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.09691
Match: 1b70A
Description: Phenyl-tRNA synthetase (PheRS) alpha subunit, PheS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phenylalanine-tRNA ligase activity 13.8919118344182 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 12.5698315343202 bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds 12.5698315343202 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 12.5592545638101 bayes_pls_golite062009
ligase activity 6.92073480193262 bayes_pls_golite062009
glycine-tRNA ligase activity 2.61548498770105 bayes_pls_golite062009
threonine-tRNA ligase activity 2.18642354927 bayes_pls_golite062009
serine-tRNA ligase activity 2.07594942154162 bayes_pls_golite062009
catalytic activity 1.99372273395202 bayes_pls_golite062009
alanine-tRNA ligase activity 1.82594054955281 bayes_pls_golite062009
lysine-tRNA ligase activity 1.72324031407565 bayes_pls_golite062009
histidine-tRNA ligase activity 1.72215103383322 bayes_pls_golite062009
asparagine-tRNA ligase activity 0.921492123574877 bayes_pls_golite062009
binding 0.705666054154871 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.00572514744734753 bayes_pls_golite062009

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