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Protein Overview: daf-16

General Information:
Name(s) found: daf-16 / CE33160 [WormBase]
Description(s) found:
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  • WBGene00000912 locus:daf-16 Forkhead box protein O status:Confirmed UniProt:O16850 protein_id:CCD71853.1 [WormBase]
  • gi|71989785|ref|NP_001021597.1| abnormal DAuer Formation family member (daf-16) [Caenorhabditis elegans] [NCBI NR]
  • gi|27669464|gb|AAO21385.1| Abnormal dauer formation protein 16, isoform e [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • Abnormal dauer formation protein 16, isoform e [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE33160 WBGene00000912 locus:daf-16 status:Confirmed TR:Q86S42 protein_id:AAO21385.1 [wormpep150.fasta]
  • 33160 WBGene00000912 locus:daf-16 status:Confirmed TR:Q86S42 protein_id:AAO21385.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • locus:daf-16 status:Confirmed TR:Q86S42 protein_id:AAO21385.1 [wormpep115.fasta.reversed]
  • CE33160 WBGene00000912 locus:daf-16 status:Confirmed UniProt:Q86S42_CAEEL protein_id:AAO21385.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE33160 WBGene00000912 locus:daf-16 status:Confirmed UniProt:Q86S42_CAEEL protein_id:AAO21385.1| [wormORF-contam.fasta]
  • abnormal DAuer Formation family member (daf-16) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE33160 WBGene00000912 locus:daf-16 status:Confirmed UniProt:O16850 protein_id:AAO21385.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE33160 WBGene00000912 locus:daf-16 status:Confirmed UniProt:O16850 protein_id:CCD71853.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE33160 WBGene00000912 locus:daf-16 status:Confirmed UniProt:O16850 protein_id:CCD71853.1 Forkhead box protein O [wormpep246-ecoli-contam.fasta]
  • Isoform of O16850, Isoform e of Forkhead box protein O OS=Caenorhabditis elegans GN=daf-16 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 303 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article][IEALink to PubMed article]
    cytoplasm [IDALink to PubMed articleLink to PubMed article]
    Biological Process: response to heat [IEPLink to PubMed article]
    dauer larval development [IGILink to PubMed article]
    insulin receptor signaling pathway [IDALink to PubMed article]
    determination of adult lifespan [IGILink to PubMed article][IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IDALink to PubMed article]
    Molecular Function: transcription factor activity [IDALink to PubMed article][IEALink to PubMed article]
    protein binding [IPILink to PubMed article]
    sequence-specific DNA binding [IDALink to PubMed article][IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIQNEGAGK SSWWVINPDA KPGRNPRRTR ERSNTIETTT KAQLEKSRRG AKKRIKERAL  60
   61 MGSLHSTLNG NSIAGSIQTI SHDLYDDDSM QGAFDNVPSS FRPRTQSNLS IPGSSSRVSP 120
  121 AIGSDIYDDL EFPSWVGESV PAIPSDIVDR TDQMRIDATT HIGGVQIKQE SKPIKTEPIA 180
  181 PPPSYHELNS VRGSCAQNPL LRNPIVPSTN FKPMPLPGAY GNYQNGGITP INWLSTSNSS 240
  241 PLPGIQSCGI VAAQHTVASS SALPIDLENL TLPDQPLMDT MDVDALIRHE LSQAGGQHIH 300
  301 FDL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..93] deduced N/A No confident structure predictions are available.
    2 View Details [94..303] MSA 15.165996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle