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Protein Overview: hst-1

General Information:
Name(s) found: hst-1 / CE33047 [WormBase]
Description(s) found:
Found 13 descriptions.
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  • WBGene00002028 locus:hst-1 N-heparan sulfate sulfotransferase status:Confirmed UniProt:Q966W3 protein_id:CCD67652.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 715 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: sulfotransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQWNRQLLD KYCKEYRVPM FSFMSSKPND QLKRIKIKGS SLWMWQNQRI QRLAVTPSII  60
   61 HRISKIGNYR QFSSSDPADW ILFETSEKFE SVLSGTVKSG YERAVVVRDK GLEDGVERII 120
  121 FGRNLTDFQV KITFLDALWW AMGNQKSFTL DRFVQVDIDD VFVGAQGTRI VEEDVRKLIS 180
  181 TQKEFRNYVQ NFTFMLGFSG SYFRNGDDLE DRGDEFLVEN AEKFVWFPHM WRHNHAHEHN 240
  241 FTYLEAIMAQ NKLFAQNMHL PVDYPYAIAP QHDGVFPVHE QLFRAWRKVW NVSVTATEEY 300
  301 PHFKPATARK GFIHAGIHVL PRQTCGLYTH TQLFDEYPEG FDKVQKSIEG GDLFFTILLN 360
  361 PISIFMTHQQ NYAYDRLALY TFENLFRFIK CWTNIKLKWQ DPLTSSQLYF QKFPDERTPL 420
  421 WTNPCTDPRH HAILPPSINC TKKSLPDLLI IGPQKTGSTA LASFLSLHPN TSQNTPVPGS 480
  481 FEEVQFFGGQ NYLKGVEWYM SNFPSSSTVT FEKSATYFDN PSAPKQAASL VPHAKIVIIL 540
  541 QNPAQRAYSW FQHILAHEDP VAITAGSLEV ILDSNSTSSK KVRQRCISGG RYVHHLTKWL 600
  601 EHFSLQQMIF VDSDELKMKP PTVLNSLSKW LDLPEFPFET YIRYSPSKGF HCRLLDGKTK 660
  661 CLGESKGRKY PEMPENLRRK LDKIFSLDNS ALYKFLRKNR LKIPTWLEES VRIRA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..206] MSA 1.020915 View MSA. No confident structure predictions are available.
    2 View Details [207..395] MSA 1.056921 View MSA. No confident structure predictions are available.
    3 View Details [396..715] PSI-BLAST 60.69897 Heparan sulfate N-deacetylase/N-sulfotransferase domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • nucleoside-triphosphatase activity
    		•  1.02433892333256 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.989469851846122 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.980088098062305 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.976945962392631 bayes_pls_golite062009
  • binding
    		•  0.837538244475264 bayes_pls_golite062009
  • ATPase activity
    		•  0.508559099342241 bayes_pls_golite062009
  • transporter activity
    		•  0.48424022775161 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.43068338046008 bayes_pls_golite062009
  • hydrolase activity
    		•  0.410543385742586 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  0.366003414070823 bayes_pls_golite062009
  • catalytic activity
    		•  0.234613562021476 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.229052859670546 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.221848871525989 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.190228662787185 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.186067331649217 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.185248585258315 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.0712149467387941 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle