YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: unc-22

General Information:
Name(s) found: unc-22 / CE33017 [WormBase]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • WBGene00006759 locus:unc-22 Twitchin status:Partially_confirmed UniProt:Q23551 protein_id:CAA98064.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 6839 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    A band [IDALink to PubMed article]
    proteinaceous extracellular matrix [IEALink to PubMed article]
    Biological Process: tRNA aminoacylation for protein translation [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    signal transduction [IEALink to PubMed article]
    locomotion [IMPLink to PubMed article]
    cell adhesion [IEALink to PubMed article]
    blood coagulation [IEALink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    translation [IEALink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    magnesium ion binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    aminoacyl-tRNA ligase activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    non-membrane spanning protein tyrosine kinase activity [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGAPRFTQK PSIQQTPTGD LLMECHLEAD PQPTIAWQHS GNLLEPSGRV VQTLTPLGGS  60
   61 LYKATLVIKE PNAGDGGAYK CTARNQLGES NANINLNFAG AGGDEAKSRG PSFVGKPRII 120
  121 PKDGGALIVM ECKVKSASTP VAKWMKDGVP LSMGGLYHAI FSDLGDQTYL CQLEIRGPSS 180
  181 SDAGQYRCNI RNDQGETNAN LALNFEEPDP SERQERKRST ASPRPSSRGP GSRPSSPKKS 240
  241 MKSREGTPKR TLKPREGSPS KKLRSRTSTP VNEEVSQSES RRSSRTDKME VDQVSGASKR 300
  301 KPDGLPPPGG DEKKLRAGSP STRKSPSRKS ASPTPSRKGS SAGGAASGTT GASASATSAT 360
  361 SGGSASSDAS RDKYTRPPIV LEASRSQTGR IGGSVVLEVQ WQCHSSTIIE WYRDGTLVRN 420
  421 SSEYSQSFNG SIAKLQVNKL TEEKSGLYKC HAKCDYGEGQ SSAMVKIEQS DVEEELMKHR 480
  481 KDAEDEYQKE EQKSQTLQAE TKKRVARRSK SKSKSPAPQA KKSTTSESGR QEASEVEHKR 540
  541 SSSVRPDPDE ESQLDEIPSS GLTIPEERRR ELLGQVGESD DEVSESISEL PSFAGGKPRR 600
  601 KTDDKPKKVS IAPVSTNKSS DDEPSTPRRR SSIDMRRESV QEILEKTSTP LVPSGASGSA 660
  661 PKIVEVPENV TVVENETAIL TCKVSGSPAP TFRWFKGSRE VISGGRFKHI TDGKEHTVAL 720
  721 ALLKCRSQDE GPYTLTIENV HGTDSADVKL LVTSDNGLDF RAMLKHRESQ AGFQKDGEGG 780
  781 GAGGGGGEKK PMTEAERRQS LFPGKKVEKW DIPLPEKTVQ QQVDKICEWK CTYSRPNAKI 840
  841 RWYKDRKEIF SGGLKYKIVI EKNVCTLIIN NPEVDDTGKY TCEANGVPTH AQLTVLEPPM 900
  901 KYSFLNPLPN TQEIYRTKQA VLTCKVNTPR APLVWYRGSK AIQEGDPRFI IEKDAVGRCT 960
  961 LTIKEVEEDD QAEWTARITQ DVFSKVQVYV EEPRHTFVVP MKSQKVNESD LATLETDVND1020
 1021 KDAEVVWWHD GKRIDIDGVK FKVESSNRKR RLIINGARIE DHGEYKCTTK DDRTMAQLIV1080
 1081 DAKNKFIVAL KDTEVIEKDD VTLMCQTKDT KTPGIWFRNG KQISSMPGGK FETQSRNGTH1140
 1141 TLKIGKIEMN EADVYEIDQA GLRGSCNVTV LEAEKRPILN WKPKKIEAKA GEPCVVKVPF1200
 1201 QIKGTRRGDP KAQILKNGKP IDEEMRKLVE VIIKDDVAEI VFKNPQLADT GKWALELGNS1260
 1261 AGTALAPFEL FVKDKPKPPK GPLETKNVTA EGLDLVWGTP DPDEGAPVKA YIIEMQEGRS1320
 1321 GNWAKVGETK GTDFKVKDLK EHGEYKFRVK ALNECGLSDP LTGESVLAKN PYGVPGKPKN1380
 1381 MDAIDVDKDH CTLAWEPPEE DGGAPITGYI IERREKSEKD WHQVGQTKPD CCELTDKKVV1440
 1441 EDKEYLYRVK AVNKAGPGDP CDHGKPIKMK AKKASPEFTG GGIKDLRLKV GETIKYDVPI1500
 1501 SGEPLPECLW VVNGKPLKAV GRVKMSSERG KHIMKIENAV RADSGKFTIT LKNSSGSCDS1560
 1561 TATVTVVGRP TPPKGPLDIA DVCADGATLS WNPPDDDGGD PLTGYIVEAQ DMDNKGKYIE1620
 1621 VGKVDPNTTT LKVNGLRNKG NYKFRVKAVN NEGESEPLSA DQYTQIKDPW DEPGKPGRPE1680
 1681 ITDFDADRID IAWEPPHKDG GAPIEEYIVE VRDPDTKEWK EVKRVPDTNA SISGLKEGKE1740
 1741 YQFRVRAVNK AGPGQPSEPS EKQLAKPKFI PAWLKHDNLK SITVKAGATV RWEVKIGGEP1800
 1801 IPEVKWFKGN QQLENGIQLT IDTRKNEHTI LCIPSAMRSD VGEYRLTVKN SHGADEEKAN1860
 1861 LTVLDRPSKP NGPLEVSDVF EDNLNLSWKP PDDDGGEPIE YYEVEKLDTA TGRWVPCAKV1920
 1921 KDTKAHIDGL KKGQTYQFRV KAVNKEGASD ALSTDKDTKA KNPYDEPGKT GTPDVVDWDA1980
 1981 DRVSLEWEPP KSDGGAPITQ YVIEKKGKHG RDWQECGKVS GDQTNAEILG LKEGEEYQFR2040
 2041 VKAVNKAGPG EASDPSRKVV AKPRNLKPWI DREAMKTITI KVGNDVEFDV PVRGEPPPKK2100
 2101 EWIFNEKPVD DQKIRIESED YKTRFVLRGA TRKHAGLYTL TATNASGSDK HSVEVIVLGK2160
 2161 PSSPLGPLEV SNVYEDRADL EWKVPEDDGG APIDHYEIEK MDLATGRWVP CGRSETTKTT2220
 2221 VPNLQPGHEY KFRVRAVNKE GESDPLTTNT AILAKNPYEV PGKVDKPELV DWDKDHVDLA2280
 2281 WNAPDDGGAP IEAFVIEKKD KNGRWEEALV VPGDQKTATV PNLKEGEEYQ FRISARNKAG2340
 2341 TGDPSDPSDR VVAKPRNLAP RIHREDLSDT TVKVGATLKF IVHIDGEPAP DVTWSFNGKG2400
 2401 IGESKAQIEN EPYISRFALP KALRKQSGKY TITATNINGT DSVTINIKVK SKPTKPKGPI2460
 2461 EVTDVFEDRA TLDWKPPEDD GGEPIEFYEI EKMNTKDGIW VPCGRSGDTH FTVDSLNKGD2520
 2521 HYKFRVKAVN SEGPSDPLET ETDILAKNPF DRPDRPGRPE PTDWDSDHVD LKWDPPLSDG2580
 2581 GAPIEEYQIE KRTKYGRWEP AITVPGGQTT ATVPDLTPNE EYEFRVVAVN KGGPSDPSDA2640
 2641 SKAVIAKPRN LKPHIDRDAL KNLTIKAGQS ISFDVPVSGE PAPTVTWHWP DNREIRNGGR2700
 2701 VKLDNPEYQS KLVVKQMERG DSGTFTIKAV NANGEDEATV KINVIDKPTS PNGPLDVSDV2760
 2761 HGDHVTLNWR APDDDGGIPI ENYVIEKYDT ASGRWVPAAK VAGDKTTAVV DGLIPGHEYK2820
 2821 FRVAAVNAEG ESDPLETFGT TLAKDPFDKP GKTNAPEITD WDKDHVDLEW KPPANDGGAP2880
 2881 IEEYVVEMKD EFSPFWNDVA HVPAGQTNAT VGNLKEGSKY EFRIRAKNKA GLGDPSDSAS2940
 2941 AVAKARNVPP VIDRNSIQEI KVKAGQDFSL NIPVSGEPTP TITWTFEGTP VESDDRMKLN3000
 3001 NEDGKTKFHV KRALRSDTGT YIIKAENENG TDTAEVKVTV LDHPSSPRGP LDVTNIVKDG3060
 3061 CDLAWKEPED DGGAEISHYV IEKQDAATGR WTACGESKDT NFHVDDLTQG HEYKFRVKAV3120
 3121 NRHGDSDPLE AREAIIAKDP FDRADKPGTP EIVDWDKDHA DLKWTPPADD GGAPIEGYLV3180
 3181 EMRTPSGDWV PAVTVGAGEL TATVDGLKPG QTYQFRVKAL NKAGESTPSD PSRTMVAKPR3240
 3241 HLAPKINRDM FVAQRVKAGQ TLNFDVNVEG EPAPKIEWFL NGSPLSSGGN THIDNNTDNN3300
 3301 TKLTTKSTAR ADSGKYKIVA TNESGKDEHE VDVNILDIPG APEGPLRHKD ITKESVVLKW3360
 3361 DEPLDDGGSP ITNYVVEKQE DGGRWVPCGE TSDTSLKVNK LSEGHEYKFR VKAVNRQGTS3420
 3421 APLTSDHAIV AKNPFDEPDA PTDVTPVDWD KDHVDLEWKP PANDGGAPID AYIVEKKDKF3480
 3481 GDWVECARVD GKTTKATADN LTPGETYQFR VKAVNKAGPG KPSDPTGNVV AKPRRMAPKL3540
 3541 NLAGLLDLRI KAGTPIKLDI AFEGEPAPVA KWKANDATID TGARADVTNT PTSSAIHIFS3600
 3601 AVRGDTGVYK IIVENEHGKD TAQCNVTVLD VPGTPEGPLK IDEIHKEGCT LNWKPPTDNG3660
 3661 GTDVLHYIVE KMDTSRGTWQ EVGTFPDCTA KVNKLVPGKE YAFRVKAVNL QGESKPLEAE3720
 3721 EPIIAKNQFD VPDPVDKPEV TDWDKDRIDI KWNPTANNGG APVTGYIVEK KEKGSAIWTE3780
 3781 AGKTPGTTFS ADNLKPGVEY EFRVIAVNAA GPSDPSDPTD PQITKARYLK PKILTASRKI3840
 3841 KIKAGFTHNL EVDFIGAPDP TATWTVGDSG AALAPELLVD AKSSTTSIFF PSAKRADSGN3900
 3901 YKLKVKNELG EDEAIFEVIV QDRPSAPEGP LEVSDVTKDS CVLNWKPPKD DGGAEISNYV3960
 3961 VEKRDTKTNT WVPVSAFVTG TSITVPKLTE GHEYEFRVMA ENTFGRSDSL NTDEPVLAKD4020
 4021 PFGTPGKPGR PEIVDTDNDH IDIKWDPPRD NGGSPVDHYD IERKDAKTGR WIKVNTSPVQ4080
 4081 GTAFSDTRVQ KGHTYEYRVV AVNKAGPGQP SDSSAAATAK PMHEAPKFDL DLDGKEFRVK4140
 4141 AGEPLVITIP FTASPQPDIS WTKEGGKPLA GVETTDSQTK LVIPSTRRSD SGPVKIKAVN4200
 4201 PYGEAEANIK ITVIDKPGAP ENITYPAVSR HTCTLNWDAP KDDGGAEIAG YKIEYQEVGS4260
 4261 QIWDKVPGLI SGTAYTVRGL EHGQQYRFRI RAENAVGLSD YCQGVPVVIK DPFDPPGAPS4320
 4321 TPEITGYDTN QVSLAWNPPR DDGGSPILGY VVERFEKRGG GDWAPVKMPM VKGTECIVPG4380
 4381 LHENETYQFR VRAVNAAGHG EPSNGSEPVT CRPYVEKPGA PDAPRVGKIT KNSAELTWNR4440
 4441 PLRDGGAPID GYIVEKKKLG DNDWTRCNDK PVRDTAFEVK NLGEKEEYEF RVIAVNSAGE4500
 4501 GEPSKPSDLV LIEEQPGRPI FDINNLKDIT VRAGETIQIR IPYAGGNPKP IIDLFNGNSP4560
 4561 IFENERTVVD VNPGEIVITT TGSKRSDAGP YKISATNKYG KDTCKLNVFV LDAPGKPTGP4620
 4621 IRATDIQADA MTLSWRPPKD NGGDAITNYV VEKRTPGGDW VTVGHPVGTT LRVRNLDANT4680
 4681 PYEFRVRAEN QYGVGEPLET DDAIVAKNPF DTPGAPGQPE AVETSEEAIT LQWTRPTSDG4740
 4741 GAPIQGYVIE KREVGSTEWT KAAFGNILDT KHRVTGLTPK KTYEFRVAAY NAAGQGEYSV4800
 4801 NSVPITADNA PTRPKINMGM LTRDILAYAG ERAKILVPFA ASPAPKVTFS KGENKISPTD4860
 4861 PRVKVEYSDF LATLTIEKSE LTDGGLYFVE LENSQGSDSA SIRLKVVDKP ASPQHIRVED4920
 4921 IAPDCCTLYW MPPSSDGGSP ITNYIVEKLD LRHSDGKWEK VSSFVRNLNY TVGGLIKDNR4980
 4981 YRFRVRAETQ YGVSEPCELA DVVVAKYQFE VPNQPEAPTV RDKDSTWAEL EWDPPRDGGS5040
 5041 KIIGYQVQYR DTSSGRWINA KMDLSEQCHA RVTGLRQNGE FEFRIIAKNA AGFSKPSPPS5100
 5101 ERCQLKSRFG PPGPPIHVGA KSIGRNHCTI TWMAPLEDGG SKITGYNVEI REYGSTLWTV5160
 5161 ASDYNVREPE FTVDKLREFN DYEFRVVAIN AAGKGIPSLP SGPIKIQESG GSRPQIVVKP5220
 5221 EDTAQPYNRR AVFTCEAVGR PEPTARWLRN GRELPESSRY RFEASDGVYK FTIKEVWDID5280
 5281 AGEYTVEVSN PYGSDTATAN LVVQAPPVIE KDVPNTILPS GDLVRLKIYF SGTAPFRHSL5340
 5341 VLNREEIDMD HPTIRIVEFD DHILITIPAL SVREAGRYEY TVSNDSGEAT TGFWLNVTGL5400
 5401 PEAPQGPLHI SNIGPSTATL SWRPPVTDGG SKITSYVVEK RDLSKDEWVT VTSNVKDMNY5460
 5461 IVTGLFENHE YEFRVSAQNE NGIGAPLVSE HPIIARLPFD PPTSPLNLEI VQVGGDYVTL5520
 5521 SWQRPLSDGG GRLRGYIVEK QEEEHDEWFR CNQNPSPPNN YNVPNLIDGR KYRYRVFAVN5580
 5581 DAGLSDLAEL DQTLFQASGS GEGPKIVSPL SDLNEEVGRC VTFECEISGS PRPEYRWFKG5640
 5641 CKELVDTSKY TLINKGDKQV LIINDLTSDD ADEYTCRATN SSGTRSTRAN LRIKTKPRVF5700
 5701 IPPKYHGGYE AQKGETIELK IPYKAYPQGE ARWTKDGEKI ENNSKFSITT DDKFATLRIS5760
 5761 NASREDYGEY RVVVENSVGS DSGTVNVTVA DVPEPPRFPI IENILDEAVI LSWKPPALDG5820
 5821 GSLVTNYTIE KREAMGGSWS PCAKSRYTYT TIEGLRAGKQ YEFRIIAENK HGQSKPCEPT5880
 5881 APVLIPGDER KRRRGYDVDE QGKIVRGKGT VSSNYDNYVF DIWKQYYPQP VEIKHDHVLD5940
 5941 HYDIHEELGT GAFGVVHRVT ERATGNNFAA KFVMTPHESD KETVRKEIQT MSVLRHPTLV6000
 6001 NLHDAFEDDN EMVMIYEFMS GGELFEKVAD EHNKMSEDEA VEYMRQVCKG LCHMHENNYV6060
 6061 HLDLKPENIM FTTKRSNELK LIDFGLTAHL DPKQSVKVTT GTAEFAAPEV AEGKPVGYYT6120
 6121 DMWSVGVLSY ILLSGLSPFG GENDDETLRN VKSCDWNMDD SAFSGISEDG KDFIRKLLLA6180
 6181 DPNTRMTIHQ ALEHPWLTPG NAPGRDSQIP SSRYTKIRDS IKTKYDAWPE PLPPLGRISN6240
 6241 YSSLRKHRPQ EYSIRDAFWD RSEAQPRFIV KPYGTEVGEG QSANFYCRVI ASSPPVVTWH6300
 6301 KDDRELKQSV KYMKRYNGND YGLTINRVKG DDKGEYTVRA KNSYGTKEEI VFLNVTRHSE6360
 6361 PLKFEPLEPM KKAPSPPRVE EFKERRSAPF FTFHLRNRLI QKNHQCKLTC SLQGNPNPTI6420
 6421 EWMKDGHPVD EDRVQVSFRS GVCSLEIFNA RVDDAGTYTV TATNDLGVDV SECVLTVQTK6480
 6481 GGEPIPRVSS FRPRRAYDTL STGTDVERSH SYADMRRRSL IRDVSPDVRS AADDLKTKIT6540
 6541 NELPSFTAQL SDSETEVGGS AEFSAAVSGQ PEPLIEWLHN GERISESDSR FRASYVAGKA6600
 6601 TLRISDAKKS DEGQYLCRAS NSAGQEQTRA TLTVKGDQPL LNGHAGQAVE SELRVTKHLG6660
 6661 GEIVNNGESV TFEARVQGTP EEVLWMRNGQ ELTNGDKTSI SQDGETLSFT INSADASDAG6720
 6721 HYQLEVRSKG TNLVSVASLV VVGEKADPPV TRLPSSVSAP LGGSTAFTIE FENVEGLTVQ6780
 6781 WFRGSEKIEK NERVKSVKTG NTFKLDIKNV EQDDDGIYVA KVVKEKKAIA KYAAALLLV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle