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Protein Overview: amt-3

General Information:
Name(s) found: amt-3 / CE32912 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00000135 locus:amt-3 Putative ammonium transporter 3 status:Partially_confirmed UniProt:Q21565 protein_id:CAA91293.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 687 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: transport [IEALink to PubMed article]
    Molecular Function: ammonium transmembrane transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGPEGSIFN ASAMQIVQIH HYAEGSVTPE VDKLYQDDAV WIISSSFIIF TMHSGFGLLE  60
   61 SGSVSAKDEV NIMVKNVVDV VFGGLSYWSC GFGFSYGDIP EWRNPYVGFG KFFYDPTRDY 120
  121 GTRETINQEG WSYASFLFQL SLATTASTIV SGAVAERAKL KSYILLGCIV ILIQALPAHW 180
  181 VWDKEGVFYK KGVVDFAGCS AVHLVGGIIG LIATVFLKPR RNRFNEDSVH QMSSPTNALL 240
  241 GTFLLWWGWF GINAGSVWGI TGGRWRLGAR AAVATIMASI GGGATAITIS FVKTKKLQVN 300
  301 FLINGILSSI VSITAICAVS RPWHALVIGS ISSVFSIAVL PLLDRLHIDD PVGIVPIHLT 360
  361 SSIWGMIAVG IFCEEDKYLG SATNNRSGLL YSWSFELLWV QLQCTAAILI YSATTGFLAL 420
  421 FLISKSPLGL RVTDYEEQIG ADVIEHGLAG TNVARYVLEK PLSTRTFQTV TKAITKWKML 480
  481 AKKKSRQKRM EAAKLKRQEE QETFTNGTAI ANGNGNVLHH RTNATESNGT GAPKRSNGPA 540
  541 FNNQITPLAV SSTVSTARNG PSTGRRTEST AIEIEQPIEA VPPEVVAAAV LPPEERPGPS 600
  601 TNSNVSIEAS VEKSPSSSTS RRSISIRSSP SIHTVSAIST AAPDSRPSTA SATSIISKKS 660
  661 SKNSTVGKFV KAPAPRALSP PDNNPPV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..464] PSI-BLAST 116.0 The mechanism of ammonia transport based on the crystal structure of AmtB of E. coli.
    2 View Details [465..529] deduced N/A No confident structure predictions are available.
    3 View Details [530..687] FFAS03 1.22 No description for 2j63A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ammonium transmembrane transporter activity
    		•  10.0624820335928 bayes_pls_golite062009
  • organic cation transmembrane transporter activity
    		•  9.07420898067257 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  7.57181833547312 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  7.46308808953548 bayes_pls_golite062009
  • methylammonium transmembrane transporter activity
    		•  7.38326654060024 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  7.08971867997216 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  7.03159982829686 bayes_pls_golite062009
  • transporter activity
    		•  5.3870893301235 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  5.3046132351753 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  5.16067985999244 bayes_pls_golite062009
  • high affinity secondary active ammonium transmembrane transporter activity
    		•  3.56825523857899 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  2.81164277777293 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.08017669832334 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle