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Protein Overview: brd-1

General Information:
Name(s) found: brd-1 / CE32690 [WormBase]
Description(s) found:
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  • WBGene00000265 locus:brd-1 status:Partially_confirmed UniProt:Q21209 protein_id:AAA50679.2 [WormBase]
  • gi|32565798|ref|NP_498498.2| BaRD homolog (tumor suppressor gene Bard1) family member (brd-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|24942999|gb|AAA50679.2| Bard homolog (tumor suppressor gene bard1) protein 1 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep104.fasta]
  • CE32690 WBGene00000265 locus:brd-1 status:Partially_confirmed TR:Q21209 protein_id:AAA50679.2 [wormpep150.fasta]
  • 32690 WBGene00000265 locus:brd-1 status:Partially_confirmed TR:Q21209 protein_id:AAA50679.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • BRCA1-associated Ring Domain protein (brd-1) [Caenorhabditis elegans]gi|24942999|gb|AAA50679.2| Bard homolog (tumor suppressor gene bard1) protein 1 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:brd-1 status:Partially_confirmed TR:Q21209 protein_id:AAA50679.2 [wormpep115.fasta.reversed]
  • CE32690 WBGene00000265 locus:brd-1 status:Partially_confirmed UniProt:Q21209_CAEEL protein_id:AAA50679.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE32690 WBGene00000265 locus:brd-1 status:Partially_confirmed UniProt:Q21209_CAEEL protein_id:AAA50679.2| [wormORF-contam.fasta]
  • BaRD homolog (tumor suppressor gene Bard1) family member (brd-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Bard homolog (tumor suppressor gene bard1) protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE32690 WBGene00000265 locus:brd-1 status:Partially_confirmed UniProt:Q21209 protein_id:AAA50679.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
    • Organism: Caenorhabditis elegans
    Length: 670 amino acids

    Gene Ontology:
    Cellular Component: BRCA1-BARD1 complex [IPILink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: DNA repair [IMPLink to PubMed article]
    cell death [IMPLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    response to DNA damage stimulus [IMPLink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    protein binding [IEALink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFENTKKALE TFRTAIECVK CKKPRGDLQY LGSSCKHAYC WECIATFQQK PSGKRSSVAR  60
   61 HMCPSCAFPL DTSKITEAHM LKTCFDTLSE LNDLLQKVGT TSLTQAEFAC TQNIFNKEKT 120
  121 PADAVEKFLE TQAHMPDEMG QLGEEDDDLM CKDENRENSN SPELDIFHDY SKEASPTRNS 180
  181 TKRPSTVSVH ERKPKRTLTE ILQRRSTAPA ATGVATYAQA FGSSSNPVKA EIIEEDIFSK 240
  241 AIPLTKRQAS MSASAKKQPK LEPEEPEEVP STSRSRKNSI KSDKIERRSQ SPMSFGEKSM 300
  301 SVKSEQRRSS YGTRRGEAVL VNSIRNNRIP QLRSAVEAGT CVNEKEDGKT PLYVAVENSS 360
  361 LEAVKILVEA GAVINASCGS TLETTLHEAV RRQNTQIVEY LLSKGASIKI RNIAGKTVEE 420
  421 MAKSDPKIRK IIEKFKTEQR VLQPVVAPPK SRLHFVQLID EKMLTESEKR KLPGKINIVP 480
  481 ADMDSPTHVV VTVDLKTRVL NINKEHIGEI LKAIIKSGMI VSRDWLRACI IDPSKVDDDR 540
  541 SYMVQKVRWM EGEVFENTIE QWKKTITKMQ PKLFAGCKFF IPKPKYNFLD RPALFEIIRS 600
  601 AGGQAAAREP IIDEKDPPPY HNANLKPNFV LYSLTHDIGD KFRDCTKYNL VSEQWLIEAI 660
  661 LGCSITTPPH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..85] FFAS03 3.82 No description for 2egpA was found.
    2 View Details [86..248] PSI-BLAST 11.154902 Swi6 ankyrin-repeat fragment
    3 View Details [249..670] PSI-BLAST 83.39794 Ankyrin-R

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • protein binding
    		•  1.85450951074782 bayes_pls_golite062009
  • binding
    		•  0.6767002227622 bayes_pls_golite062009
    3
    Term Confidence Notes
  • protein binding
    		•  1.85450951074782 bayes_pls_golite062009
  • binding
    		•  0.6767002227622 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle