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Protein Overview: che-3

General Information:
Name(s) found: che-3 / CE32386 [WormBase]
Description(s) found:
Found 16 descriptions.
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  • WBGene00000485 locus:che-3 Cytoplasmic dynein 2 heavy chain 1 status:Partially_confirmed UniProt:Q19542 protein_id:CAA99830.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 4171 amino acids

    Gene Ontology:
    Cellular Component: cilium [IDALink to PubMed article]
    dynein complex [IEALink to PubMed article]
    proteinaceous extracellular matrix [IEALink to PubMed article]
    Biological Process: cilium assembly [IMPLink to PubMed article]
    ciliary or flagellar motility [IMPLink to PubMed article]
    protein localization [IMPLink to PubMed article]
    cell adhesion [IEALink to PubMed article]
    blood coagulation [IEALink to PubMed article]
    microtubule-based movement [IEALink to PubMed article]
    chemosensory behavior [IMPLink to PubMed article]
    negative regulation of transforming growth factor beta receptor signaling pathway [IGILink to PubMed article]
    Molecular Function: nucleotide binding [IEALink to PubMed article]
    ATPase activity [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    microtubule motor activity [IEALink to PubMed article][ISSLink to PubMed article]
    nucleoside-triphosphatase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSDSKDQRK TYFLRVASYL LGLNIVEEKL KSTEPLEIFL DSNTNLLVFS RSEQKLELSN  60
   61 KMKSSAPSAN VFRVVFYKTQ SVPLNNDNFK SVVNVISANG TLNHVFLKSV QNVFGKELTE 120
  121 GNNMQLIAAV NELEESLLAT VEMSGGGSLH DEIRSWKGQT GKPANDYNEA FKQLQLLVET 180
  181 MEERSIDELS ELVECFEDTC DELWNCGTPY PQNRMKMLIE YGASYLCETI TFKIDDSAIW 240
  241 RNDKVADQLR SAIDVCDQML IIVRLLTAQT WKRNVEHTWE GDAMEMKFLN GFKDRLDEIL 300
  301 SLKSLGGQLE ELLEERGVRE ETEKTIETAM RGMAPLAYNP FTEPNWKSRL LVSERSIEGT 360
  361 IDRTLPILKQ RLAPANGDSQ SIVLSLEKLK SFLCRSNIKE KLQHEREMFL NRLVSMLSQK 420
  421 NQEFNEKSLQ VDAKNFQFLT EVAARIVWIR QQTSQMESIR SLSKMMLNNI SNYSAFASKL 480
  481 DEFIEKLQYA EKECFDDWCR ETVGLIDNKN ETINLETTGK IMYLEASNRE LNVNYSDRLL 540
  541 RLLKEVRQLI SLGFNIPSKI MSCANNGEKY YRFGVILKQI AHFYNTIDQQ MIPSQQSLML 600
  601 EEAIAFEKLV IPRKDASNSA SKVTWNDPKQ LEEFIVQLQS AEQKLSNRNR RLRNVHMELI 660
  661 EMVEKLMDLN IVKQNNEWKE IILKIRSKMK EEEIVHGAVK NNMKPWLIHW DFQLYKALLI 720
  721 QYEWGIESIQ SQLSTISVSL VFADQKIQLR PTIEEIRSKY YKELCRFLRI PDKFRGVQED 780
  781 ENSTKFYAQM IERSMHLLPT VYEKAEQLMM KVETCDAIFV DWLVISQVDL EELIEENLKT 840
  841 AADWESQFKI LKGKAREAER LPHELKFECI LVSTAGVKSA IEDAIQRLYD ALSWTLRHSI 900
  901 STTSQSISTF LSQAIEVLNT VPQSIDEIAE ANAKHVIFAE NNRRLKEEWK VMEEQLTLLR 960
  961 SVAGTGMEQI DNLEQTWDRF ELMLDGHQSM IKDQVEVLKS NVETSVKGMK DEAEKLKARW1020
 1021 EQFKPRNDAL QGDREEMLKA IQFIKEKRVQ WQQLSDGREK IEKECGQFGL EPPKMDIIDE1080
 1081 IDEDIKQFED NWLIYEMFNN ELDTMSQEEW IVFRSKTYLF DEFLQKWMEK LKGTGSQTHM1140
 1141 SVRLMKDVEH FKEVSSALKF CRGDVLSADH WHEMFRFLGL PRGTTIEKLK FADLLSVSKN1200
 1201 IIENTDQLKQ LNSRAQGEVA IRDAIQELTL WAAQTEFTLA DYKHSNGQNL KIIKEWKESI1260
 1261 NSLKDSQALL QSLKSSPYYS QFTDKTAVWE TRLADLDVFL AQMNEIQRKW IYLEPIFGRG1320
 1321 ALPSEASRFS RVDSEYRAIL NDVSKDARLV SLCSRQSLKK SLEQIVDQLN RCQKALNQFL1380
 1381 EQKRTAFPRF YFIGDDDLLE ILGQSTNPQV IQTHMKKLFQ GINRVQFSST GETIISMVSS1440
 1441 EGETVPLSKA VRIVPQVESW LQELSDEMRR TLKDLTAQAV ADAQPSLAKY PSQVLCLAEE1500
 1501 VKFSASIENN LNGSSDLNSF KSQLLEKLKA YTNMKVDDKV SDLKLKSLIL DLIHHIDVVD1560
 1561 QLLTNQAKSI NSWTWQRQLR FYLVNGGIVL RQVSSEFEYT YEYQGNYAKL VHTPLTDKCY1620
 1621 LTLTQAMYMG LGGNPYGPAG TGKTESVKAL AALMGRQVLV FNCDEGIDVT SMGRIFTGIV1680
 1681 ECGAWGCFDE FNRLDSTVLS AVSMQIQTIQ GAIKSRAGSC TFGGKNVQVN PNSAIFVTLN1740
 1741 PAGKGYGGRQ KMPDNLKQLF RAVVMGKPDN ELISSTILYS EGFVDATALA RKIVSVFQLS1800
 1801 RQMLSKQQHY DWGLRALKVV LGGCGALRRT QTNKNETDLV VQALLLNTLS KLTFSDSERF1860
 1861 NSLIDDIFSN VTKEMTKFEE LVEPLGVAAQ EMGIKLGDKQ MEKVFQLYEQ MRQRIGVVVV1920
 1921 GAAGSGKSTI WKILQRSLIL TKKPLKVTQF NPKAVNRSKL LGNMDMDTRE WSDGIITMAA1980
 1981 REVTKDTSVH HWIVCDGDID PEWVEALNSV LDDNRLLTMP SGERIQFGSN VNFLFETDSL2040
 2041 QFASPATVSR MGMIYISEED VTPKDIVASW LVKTTEDLHA DMPSWIEEHF WRCLKWVRSH2100
 2101 KISGITSFAI LKNGLTHLKA SKTKTQFLVL LFNGFLPTVT PENRQEFAKG VVFQGMSVPD2160
 2161 PKNICYDERI DGIMSYTDDV SQNVTKEEVE REDLRPFVQT ADTQRYSDII GSWLQSGNRE2220
 2221 SFLITGTTGC GKQQLLKHCF QNDPESQLAS LYCSAQSSSS HLLQLIQQNC VQASNPTGRV2280
 2281 WRPKDRPNMI LFLKGINLPA PDKYGTNELL ALLQQLLTYQ GFFDHNLEWV SIENIQFVGS2340
 2341 MNPIGDGAAV SISNRLFSLL RCVSLNTTDS SQLTSIYRTY LTPILEEVGE RNSEIIANRM2400
 2401 VDIYNKVQSN FRPTDSVVFL FSPRDLTNWV VSLLRHELDQ GKLEAVICFE ARRIFADRLP2460
 2461 TENDKLKFEE ILRNVIPISQ ANETVIFKEK VYVTTGTVVP GESNTGLPLT PINMSDFNQL2520
 2521 LAKSINRFAF EIANFNCPLT SQLAFFCACI DRVLTGPGGH LFLPGRPGFG RRDSVRLVAH2580
 2581 MHNIQVFSPP VTANFSAKQF DNELKNAITQ AVTNNEHVVL ILEDHQLRKN IFLQAINSLL2640
 2641 ASGNVPGLFT QQELDGLVAL VSEAANQASF TGALQQFLAH RIRSLVHVVL ILEVEANDFK2700
 2701 INITENPAIL KHCNVIFADR FDRNSLVEIP KIQMESQGIT TTDAILTGFN DVLVNLPEHL2760
 2761 SIQPIKYRQF VENFFQLLGY KRLTLSVRLE RLKGGVSKLN EARDEVAKMQ KKAGKKSKLL2820
 2821 AEKQAEADEA LKAITESMSG AEDQKLSMEQ LKAATEKENV RIEEQKAKID EQLKEVQPLI2880
 2881 DEARRAVGSI KSESLSEIRS LRAPPEAVRD ILQAVLLFMG ILDTSWEAMR KFLSKSGVKD2940
 2941 DIMNFDANRI TNEIHKKVTA LVKQKSNSFE EANAKRASAA AAPLAAWVKA NLEYSKILEK3000
 3001 IAPLEGEKNK LVKNLKKAEK QMENLSKGLQ SVDEVVGELK RKFEVLMKEA TQIKVDLDRE3060
 3061 QDTIRIAGTL VESLSGEFER WKIQIETFGE EQSKMELCSL ITSAFITYLG GCSEKDRKSL3120
 3121 LKSMCKMFNM PPTFKPLSFA SLETEQLNWK TKGLPADQLS LENGSILFTS CHAPLIIDRS3180
 3181 GQVSLFLSKF LEKSETFKAA QPDLMTQIEL AIRFGKTIII DDIVEFDSAL IPILRKDLSS3240
 3241 QGPRQVISFG GKSIDFNPDF KIYFCTRDEK VDIRPNSYVQ LNIVNFTTTI SALSAQLLDV3300
 3301 AIHLEKPELE ERSSSLLRDA ELKKLELEGL EQLLLQQLAS SQGNLLENTA LLDSLNKSKE3360
 3361 SAEIITKSIV ESEQLHKELT TQKDIYVPLS LFTSSLFFSF SNLQFHNPMY NYSVNTIMHL3420
 3421 FGKTIKSCED KSSTRVETLA RQMQLTVFYH ISRGIFRQDR LMFAVAFINA TMPKMFQPKE3480
 3481 WELFTGVLVD ESTDLSALRV QWISPDRLQS LARIRTHLPS LFNNFQIQDD ATWNEFSKTL3540
 3541 QCENAFPKNV ELKMTHFQKV LFIQAVKPER LYNCLMDFVL KTLNIPSINP PAFELKHIFQ3600
 3601 ESESTEPILF ILADGADPSQ ELSEFASSMN VPYHSISMGQ GQEIAAYEAI RESASKGEWL3660
 3661 CLNNLHLMLQ AVPSIFKHLS LTTPHENFRL WLTTEGDARF PSMMLQQSLK ITFEPPPGVR3720
 3721 NNLLRTYTQI DRSTKNVITC QSIFVLAWLH ALLQERRTFI PQGWTKFYEF GASDVRVAKS3780
 3781 FVEQLTANKA DWEFVRGILK FVIYGGRIEN DFDFKVLDSY LNVLFCDEKI NGRAGSQLVK3840
 3841 GIDLLATTNV QEYIGHISKS VPSVDEPYLF GLPENIKYSW QIVEADRTIS SIRTLALGDT3900
 3901 KNALSDQSDK ISQIVSLWKK LCQSDDLPKR ELPTAIRSAD PISEVLCLET INALSLIKQL3960
 3961 HRSIGHVAKS MKTPSLASPA VQKTIQSLVF QQTPDEWDSM WAGPSDPADY LNVVVKKTRG4020
 4021 TLQLFESSKS SSLLSSPIDF SDLFYPNIFL NALRQTTSRQ IKIPLDQLIL SSAWTPSQLP4080
 4081 AKQCVQVQGL LLQGATFDSF LRETTVSSAA YSQAPIVFLA WTSESSSTIT GEQIQVPVYS4140
 4141 SSERSDLICS VNMPCRGADQ WNIAAVALFL R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle