Protein Overview: eel-1

General Information:
Name(s) found:	eel-1 / CE31665 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00022069 locus:eel-1 status:Partially_confirmed UniProt:Q9GUP2 protein_id:CCD74094.1 [WormBase] gi\|25148695\|ref\|NP_500284.2\| Enhancer of EfL-1 mutant phenotype family member (eel-1) [Caenorhabditis elegans] [NCBI NR] gi\|22532851\|gb\|AAG23375.2\| Enhancer of efl-1 mutant phenotype protein 1, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] [wormpep88.fasta] CE31665 WBGene00022069 status:Partially_confirmed TR:Q9GUP2 protein_id:AAG23375.2 [wormpep150.fasta] 31665 WBGene00022069 status:Partially_confirmed TR:Q9GUP2 protein_id:AAG23375.2 [wormpep130-phg-ecoli-orf-rand.fasta] ubiquitin-associated domain and HECT domain containing protein (4D798) [Caenorhabditis elegans]gi\|22532851\|gb\|AAG23375.2\| Hypothetical protein Y67D8C.5 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] status:Partially_confirmed TR:Q9GUP2 protein_id:AAG23375.2 [wormpep115.fasta.reversed] CE31665 WBGene00022069 locus:eel-1 status:Partially_confirmed UniProt:Q9GUP2_CAEEL protein_id:AAG23375.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE31665 WBGene00022069 locus:eel-1 status:Partially_confirmed UniProt:Q9GUP2_CAEEL protein_id:AAG23375.2\| [wormORF-contam.fasta] Hypothetical protein Y67D8C.5 [Caenorhabditis elegans] [nr-271106-contam.fasta] Y67D8C.5 [Caenorhabditis elegans] [nr-271106-contam.fasta] CE31665 WBGene00022069 locus:eel-1 status:Partially_confirmed TR:Q9GUP2 protein_id:AAG23375.2 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE31665 WBGene00022069 locus:eel-1 status:Partially_confirmed UniProt:Q9GUP2 protein_id:AAG23375.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] CE31665 WBGene00022069 locus:eel-1 status:Partially_confirmed UniProt:Q9GUP2 protein_id:CCD74094.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] Isoform of U4PBY0, Enhancer of EfL-1 mutant phenotype OS=Caenorhabditis elegans GN=eel-1 PE=1 SV=2 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	4177 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA] intracellular [IEA] proteinaceous extracellular matrix [IEA]
Biological Process:	DNA repair [IEA] nematode larval development [IMP] embryonic development ending in birth or egg hatching [IMP] protein modification process [IEA] cell adhesion [IEA] blood coagulation [IEA] ubiquitin cycle [IEA] mRNA transport [IEA]
Molecular Function:	ubiquitin-protein ligase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIDDAEPSS SSSGSDMPPA SATLLRNIVA TKNDEDFIAA INKGREVHAV MGKTELYKWT  60
   61 EVLNRCDEIL EKAVHKNEFG NLQCDHDTVL KNHAVAIVRF TVLLFECTSS RRIYKSVDRI 120
  121 LALLESTDMD LLAEVLRLLQ VMGKRSKFLS TRIPQKEQHA LAQRLTAIAQ CWGGKLRTVK 180
  181 MAECLKREPK LPMLFPFTYT DAKQRTIIVE QPKKDESVGE LITRTVAQIS PPVSSDSVPS 240
  241 QQFSKEDLYC LLSRVRMLVT FEDWHHRFKC LIVRLLSVST LVYCRLGGTD ETTLSSLLYS 300
  301 GFIEEIVEML KSDREADTQQ DHNLHDAIQT EALSTLCSIV TYEKEPKITQ ILEALSAGSY 360
  361 HGFLSVMTRQ IVDELKSNNL GKTGKPSVSL ATALFSFIYH LASIEPGGDT LVGSGLTQTL 420
  421 LSVIGFHELP IECITFGTRC ARIIDLFTTI DVTSFKANNG MEICVNRVVH EINECRKEQP 480
  481 FMIDISYDMP FEEEPEPRDD QEAHEEPEDE SDERNPVDQE APVPIEVDAP LPPASPIAAP 540
  541 APVPVASAST SSDSKIKGGP WEEVQMNGAT CHQQRSGLIK GLLTFIKRAI GDVQFQDIMK 600
  601 HLMEGDLPEA LMHILSNAEY YSPSLFHQSA HLITNFVYQF PEELSSIQRR HVPYVIFQSL 660
  661 LRKELPNSKD VITTLGNVFT AMCLNERGLR QFKSYDPFNQ IFRIVLSVKF LVTLRKKRSA 720
  721 EVFESAQAIG GALDDLMRHY PDLKHDMLKS IIVILDLLDE IGRNPPAGVE LVPTLTKTMA 780
  781 RSVVFSPNNS SLLPREAREA RELRIQQLQR EIPEQADERV GGDVEEEPME VEDAEDSDVD 840
  841 EEDNEMSMDE MSGEAPAPPA APSPKPTKPF EYGAGMMCED ANGKKILPIG DYMLLIARVV 900
  901 ETMMTQSPSQ KITEEFIDEC VMQKIMKLCH LPCITNEATH ATYIGSIANI IKHIVKAGYQ 960
  961 SQRNGPDVGP KLMSAIVGEF IKTINPLFEV NNGDFSAMNQ AESRKATLLM HLDEKLVEKT1020
 1021 LVELNSIIPT LLNLNKSPMS STYNPQDHRT RIYETWKMPE GMKLYGMLRK LSRMLCWEYE1080
 1081 LVQTLKPTIR TAATQTEGEM LSDQPADTHL DVEVMPPWDE DSVDEQQKRD EAKEPRWKAA1140
 1141 GVSQEEHDFW IKNKPLQDIV SKSHAMVKDL LNSMGKTINV NNPRRPRIRD TPPLPLAASH1200
 1201 CISMIFSSIY KDLKWEPPVQ NAATSPMAYG RYIELLTQLN HSLFENGRCS NPALPQNFYT1260
 1261 SGCHKAFFEL FSDKIIPFLG DNMPEGVEQT MEEWCRLAVK LTDRNTIVSS DNWQRRDRQS1320
 1321 ADFDTNKYLK LVCRDMFNAY KQFFEKMAQM PDWELKSLKK VCENAFSVFK EVAKNLVEET1380
 1381 EATTAATEAV NAAAAPAPAD APAAEWGPGA LRIPPVAVEP APAPVAVNPA AAADPHEDTI1440
 1441 VMLMDLGFSR DIVLYALEST RNADEAANYL LAHGNEIPLQ DAANPFRDDL LNQVLREAGA1500
 1501 EMIAGANTPN ADEIELQLNA QFAEHQGYEL VRIAQRVLRD AGAEQIGLQI MEAYPDESVD1560
 1561 VAAEQLINDV MDRVRNPRSS YEENIAQPLI PPLSQLKIEQ DVSLNSACKQ LFPLVKRLLL1620
 1621 VSNDTIHPCA ELIVSIFPAM TEEWRKEHLI AEICGEDLKN MAKSLVEQEV DENGRPKQHD1680
 1681 VARTMTNRLH FAVLIFDKIS EEYVQWIDAN GMTEVMLTSL EYLVERFKSV DYYQSLITRI1740
 1741 ICWNDFYAKT HRLIVRRAYL KSLSPSLVWS YQSYEEDALR RRADYSSGEK KWVPYDAASQ1800
 1801 KTLNDAFFAG VRGVKCTLKR GVRPNKKVDV DFASMKQGDG TSRENIKAEL PPTVEVSIPD1860
 1861 LMDAEAKLSW SEDQNDRFLD LSTQILRTGA LDPKCSHSML SFIARLTRSH RNAVRFMEKD1920
 1921 GVEAILRLRA RCAITYPFLV SIIIRNCIDD DALLGHIYEK TIRGYIAVPT QPPASMSEYA1980
 1981 AGKSKDFADT LNFMAPLSTR NPLVFTEAMN KLARMNGSLI LPMIKEKKPT LSVSSTAGGA2040
 2041 STSSSSAPPP PPPLTSSSSH TVVENNSRAE KIVSMMLSEV LNGEFPTVGQ TRMLSQEKIL2100
 2101 QILAEIVKSY PSLAIIIAET QAEGRSALHS LIDTYIIAPI EKIETTNALK TLIAVISASQ2160
 2161 NSLKAQELLV LDVKNALASY SEKASELRVD LAKLQLDKES EEREEATTSL KKQETEVLSK2220
 2221 ISELCSIIII MCQSCPAHHH HHHSSTDRNN RERSSQNAIM KMFHKKRMCA DLVKTIHCLQ2280
 2281 LSTKVSLDTV NQILKTLDTL LEGSTTTTSA TITGPRSLMD IVAGRREQRR EAAAGGIMNE2340
 2341 REIDTIFQRD GLAFDGEMEN LLRRLQGDHW RGNSVQRGAG QVAEEEEGSE TYEERERSDS2400
 2401 PSESSEHAGD EEVRDDAVET GDGEVDMADA QDAPLAAPDA PPGINLVDEI MQQVQRDVED2460
 2461 DEEDEDGDQN EHEAEEDDHD REDEDDEDDD DDEDEEEEAE DDDQDEDDVR HVEQNPEPLA2520
 2521 RRLFEEDDDD EEDDDGDEDG DSMEDDVQRL DLDDDYFDMG GPFDAQRMDD MIFPPSFGRP2580
 2581 AVTSFADLFR DDFDFLPPYR AERRPLARGS HLGGVISEHP LMTRPPAEND VSRRPNTNIR2640
 2641 AEILQMHTRS SLHRQNAIRR TTTEARELEA ISRGIRMGEL PAGRMLVRGT TTHGDGGVHT2700
 2701 SFFDHIFDIR PSNVAFSRSG AYRSYNTGDR DERRDIRASQ VPTCLERLES YSLSMEPVSS2760
 2761 RFVTVIVNSH LNKIHAAREA QIKKEAEIKA KAKKDAEAAK KAAEDKKKAA EAPAPAPSAE2820
 2821 QSDSPASPDA PAPAPEEIGL ATPAATNTTN TVSESVAPNA STRGDDTLTT PAAAQVEDQA2880
 2881 SEDQHIEEEP MEVGEDDGAA EAPQSSAATA ASSVAGTEEI EDVERQAVED HVPEIQDNDD2940
 2941 TLPYEGAVEH APAQAPEENV MPEEFRAILG DIIIPDGVDP AFLAALPEEM RAEVIRDYQR3000
 3001 QQRAERASRP VPAAQPVAVN PNAPAGGEAA QGEGQAEQPA AAVVPLVEPI DPVFLNALPP3060
 3061 ELQEEVLAEH ERRLREAEEQ QRRQNAPPAP VVEMDGAAVI ASLPANERAQ VLAEMDDAEL3120
 3121 AGLPADMQNE ARRARAQHVE PNMLRYHRLL FRGGVGGAPG AIGTVRARTN ARAAANAGPS3180
 3181 VGQNAGNAIQ APPDQPHLLD RESILTLCLL YLVDNNRVPH TRLQKVLRSA CVNQTTCDFI3240
 3241 VWCLLALLDK ASEANTDDEE ILSNVPAWLD SIAVSGVGHN ERAIRISENA QKISIHSMLA3300
 3301 IPMCKNILDL LANIARAYPG NFLPLILRHG AKPTDTPKQA PSFAQFWTMV QNTTKVPKSK3360
 3361 DWTATPEQQL EECPLGQMLN SLRKPIMAKS PLKEKVLKVA SQIMVTLPMD TLKLLGNDES3420
 3421 RKPLAEKLEF VIQVMTTGSC STEGLADGLT ILSEAMRSLS DSTSVDIYEH LFLAVSKLGG3480
 3481 ELLPQVDRLI VELDEAQKKE EVSSVAPSDQ PTSSKTAQLV VDTSAAGRVA TGRFDGERLV3540
 3541 IDGDQNMRLQ MSSCKELQLP AVTVLTDKGG AQYALLSALQ TLVKVRNHMK AIRKDKAKRA3600
 3601 KDAEKKLKEK ETPSTSAPAA PAAPATAPTA PAAPDAPVEN NEVPEPAAEL EEVNDEEPRI3660
 3661 SERLSSLESL WNSLSECLLR LGKASDPHAV LALQPAAEAF FLVHASQQNK LKAKDAEAKR3720
 3721 KESQAASSSA AAAVASSVSH DGLREDLDPD TAKLIEFAEK HRQVLNQALR QNNAVLSAGG3780
 3781 PFAILTQFPK LLDFDVKRKY FRKELTKLEP SMPRYRRNDV SVQVSRNRVF SDSFRELFRL3840
 3841 RPSEWKNRFY IIFQGEEGQD AGGLLREWFS VITREIFNPN YALFITAPGD MVTYMINKAS3900
 3901 YINPEHLDYF KFVGRLIAKS VFEHKYLDCY FTRAFYKHIL NLPVRYQDLE SEDPAFFKSL3960
 3961 DFLLQNPIDD LALDLTFSTE VEEFGVRSVR DLKPNGRKIE VNDANKDEYV KLVCQMKMTG4020
 4021 SIRKQLDAFL TGFYEIIPKD LISMFNEQEL ELLISGLPTV DIDDMAANTD YKGFQKTSTH4080
 4081 IQWFWRALRS FEKEDKAKFL QFVTGTSKVP LQGFASLEGM NGVQKFSIHM DSRGGDRLPA4140
 4141 AHTCFNQLDL PQYESYEKLR QSLLLAIREC TEGFGFA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-2	hcp2 ip from december	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: eel-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: