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Protein Overview: wah-1

General Information:
Name(s) found: wah-1 / CE31841 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00006937 locus:wah-1 status:Confirmed UniProt:Q9U229 protein_id:CAB60511.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 700 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: electron transport [IEALink to PubMed article]
    cell death [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    DNA fragmentation involved in apoptosis [IDALink to PubMed article]
    glutathione metabolic process [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    detoxification of mercury ion [IEALink to PubMed article]
    Molecular Function: NADP or NADPH binding [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article][ISSLink to PubMed article]
    FAD binding [IEALink to PubMed article][ISSLink to PubMed article]
    mercury ion binding [IEALink to PubMed article]
    mercury (II) reductase activity [IEALink to PubMed article]
    glutathione-disulfide reductase activity [IEALink to PubMed article]
    dihydrolipoyl dehydrogenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLRAVGRQM TSVIFRQQTA VRSIAMSRVA LGGGGHHHEP TPVYIPKPGS LDWTFFSRSH  60
   61 TKSAHEFEPY KPEIGAFIGA VAFIGLTLIA VVIKTDVFKK EDSHGHGHGH AKHSKKHEEK 120
  121 HEQKHEEKEH AEPEKKEEAK PEKPAEPKEP EPAQKQAEQP EQAEEKQETK DAEPKEQVDD 180
  181 RQTEEAVHAR RAPAAAEEPA PSTSKADAVE EKRSEQQSMK PSESTEENTT TTSADGLLHC 240
  241 EYVIIGSGTA AYYASLSIRA KQAEAKVLMI GEEPELPYNR PPLSKELWWY GDETSATKLA 300
  301 YTPLSGKKRD IFYEVDGFFV SPEDLPKAVH GGVALLRGRK AVKICEEDKK VILEDGTTIG 360
  361 YDKLLIATGV RPKKEQVFEE ASEEAKQKIT YFHYPADFKR VERGLADKSV QKVTIIGNGL 420
  421 LASELSYSIK RKYGENVEVH QVFEEKYPAE DILPEHIAQK SIEAIRKGGV DVRAEQKVEG 480
  481 VRKCCKNVVL KLSDGSELRT DLVVVATGEE PNSEIIEASG LKIDEKLGGV RADKCLKVGE 540
  541 NVWAAGAIAT FEDGVLGARR VSSWENAQIS GRLAGENMAT AAADGKSEGK AFWYQPSFFT 600
  601 KFAPHLHINA IGKCDSSLET VSVHAEPDKD TPLEKAVVFY KSKEDGSIVG VLLLNVFGPS 660
  661 LDVARRIIDD RKKVDEYKEI AKLFPLYDPV KSDEDDAKSA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..154] MSA 1.133996 View MSA. No confident structure predictions are available.
    2 View Details [155..221] PSI-BLAST 9.30103 Trimethylamine dehydrogenase, N-terminal domain; Trimethylamine dehydrogenase, C-terminal domain; Trimethylamine dehydrogenase, middle domain
    3 View Details [222..700] PSI-BLAST 55.045757 Apoptosis-inducing factor (AIF)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • catalytic activity
    		•  1.93817882455555 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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