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Protein Overview: asm-3

General Information:
Name(s) found: asm-3 / CE31626 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00000213 locus:asm-3 Putative sphingomyelin phosphodiesterase asm-3 status:Partially_confirmed UniProt:Q9UAY4 protein_id:CCD69084.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 589 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    vacuole [IEALink to PubMed article]
    Biological Process: sphingomyelin catabolic process [IEALink to PubMed article]
    Molecular Function: endopolyphosphatase activity [IEALink to PubMed article]
    sphingomyelin phosphodiesterase activity [IEALink to PubMed article]
    hydrolase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLGLLVLSL AFQGTLAVTE CEECKSIVDL LQFEWGEKKT EECVMEIAVF ICETFHIEDN  60
   61 DVCNFIISDF SDEFMYVIKQ ILVTPHQLCG LLMKNDCGDF VDPLATIWNM TIPGNQPPFV 120
  121 PKQVVPPGNP TLRALHLTDL HVDMFYTVGL EADCGTPQCC RPQDMNVEIV ENGDVKQPAG 180
  181 PWGSVGSCDT PYWLLTNMLQ NIASTAGKLD YIMVSGDLVS HTVWAYTPET HSFMVKNLSD 240
  241 TIRSYFPKTP VYFAVGNHEG VPVDNIAPHF TPKKYHMDWL YKAMSNAWQG WIPADQEKSL 300
  301 EYNGCYMKKI YDGLRMISLN NVYGDRINFW LYINQTDPDG TLQWLINQLQ DAENVGDKVH 360
  361 IVAHIPGSDG EALEGYALNY YKIINRYANT VVGQFFGHTH SEKFYMMYAN PDDYKSTPTN 420
  421 VVYSAPSVTP YSDYFPAYRI YTIDGVHKGS TYQVIDYEEW FFNLTSNNAN PTNVKWEVLY 480
  481 QSANMEYGLK GQIPTEYNQM IERMKTDDSL FNKYYENHNR RSIYDGRAPC NDQQCRNGYL 540
  541 CDARQFHQTQ QLCTDLEGGI QKPEPKKNKY SARFATSNER RRGKEECKI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..82] PSI-BLAST 14.221849 No description for 2gtgA was found.
    2 View Details [83..487] PSI-BLAST 39.154902 Purple acid phosphatase, N-terminal domain; Plant purple acid phosphatase, catalytic domain
    3 View Details [488..589] MSA 1.165996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.147223649904879 bayes_pls_golite062009
    2
    Term Confidence Notes
  • phosphoric ester hydrolase activity
    		•  3.05960970003903 bayes_pls_golite062009
  • hydrolase activity
    		•  2.06280293513737 bayes_pls_golite062009
  • catalytic activity
    		•  1.39852585255405 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.04077570202244 bayes_pls_golite062009
  • phosphatase activity
    		•  0.76188635342041 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  0.744264552706022 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  0.631630849060451 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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