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Protein Overview: CE31083

General Information:
Name(s) found: CE31083 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00020950 locus:dlst-1 status:Confirmed UniProt:O45148 protein_id:CCD72936.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 463 amino acids

    Gene Ontology:
    Cellular Component: pyruvate dehydrogenase complex [IEALink to PubMed article]
    oxoglutarate dehydrogenase complex [IEALink to PubMed article]
    Biological Process: nematode larval development [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    metabolic process [IEALink to PubMed article]
    glycolysis [IEALink to PubMed article]
    tricarboxylic acid cycle [IEALink to PubMed article]
    pyruvate metabolic process [IEALink to PubMed article]
    growth [IMPLink to PubMed articleLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: dihydrolipoyllysine-residue succinyltransferase activity [IEALink to PubMed article]
    acyltransferase activity [IEALink to PubMed article]
    dihydrolipoyllysine-residue acetyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGRRAVSVH RFLSRAARQS VTAASSAQPS LQAKTSLLEP LVQNVRITSS ANFHMSAVRM  60
   61 SDVITVEGPA FAESISEGDI RWLKQKGDHV NEDELVAEIE TDKTSVEVPA PQAGTIVEFL 120
  121 VEDGAKVTAK QKLYKLQPGA GGGSSSAPAK EEPKSAPAKE ESKPAPAKED SKPAVTAAAP 180
  181 PKPVSGDIPK SAPPVARPPS TPSSSTPVGA VPVTRVVVPK GVDPSHAITG ARDEVRVKAN 240
  241 RMRMRIAQRL KDAQNTYAML TTFNEIDMSS LIEMRKTYQK DFVAKHGVKL GMMSPFVRAA 300
  301 AYALQESPVV NAVLDENEIV YRHFVDISVA VATPKGLVVP VLRNVESMNY AQIELELANL 360
  361 GVKARDGKLA VEDMEGGTFT ISNGGVFGSM FGTPIINPPQ SAILGMHGVF DRVVPVNGKP 420
  421 EIRPIMQIAL TYDHRLIDGR EAVTFLKKIK TAVEDPRIMF MNL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered No Comments Cheeseman, I.M., et al. (2004)
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..232] PSI-BLAST 22.39794 The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
    2 View Details [233..463] PSI-BLAST 89.69897 Dihydrolipoamide succinyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transferase activity
    		•  0.0197121876070221 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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