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View Structure Prediction Details

Protein: CE31083
Organism: Caenorhabditis elegans
Length: 463 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE31083.

Description E-value Query
Range
Subject
Range
gi|126096730, gi... - gi|126207938|ref|YP_001053163.1| dihydrolipoyllysine-residue succinyltransferase component of 2-oxog...
gi|32034768 - gi|32034768|ref|ZP_00134893.1| COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoam...
gi|189914931, gi... - gi|190149800|ref|YP_001968325.1| dihydrolipoyllysine-residue succinyltransferase component of 2-oxog...
424.0 [0..63] [463..2]

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Predicted Domain #1
Region A:
Residues: [1-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGRRAVSVH RFLSRAARQS VTAASSAQPS LQAKTSLLEP LVQNVRITSS ANFHMSAVRM  60
   61 SDVITVEGPA FAESISEGDI RWLKQKGDHV NEDELVAEIE TDKTSVEVPA PQAGTIVEFL 120
  121 VEDGAKVTAK QKLYKLQPGA GGGSSSAPAK EEPKSAPAKE ESKPAPAKED SKPAVTAAAP 180
  181 PKPVSGDIPK SAPPVARPPS TPSSSTPVGA VPVTRVVVPK GVDPSHAITG AR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.39794
Match: 1zy8K
Description: The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [233-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEVRVKANRM RMRIAQRLKD AQNTYAMLTT FNEIDMSSLI EMRKTYQKDF VAKHGVKLGM  60
   61 MSPFVRAAAY ALQESPVVNA VLDENEIVYR HFVDISVAVA TPKGLVVPVL RNVESMNYAQ 120
  121 IELELANLGV KARDGKLAVE DMEGGTFTIS NGGVFGSMFG TPIINPPQSA ILGMHGVFDR 180
  181 VVPVNGKPEI RPIMQIALTY DHRLIDGREA VTFLKKIKTA VEDPRIMFMN L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 89.69897
Match: 1c4tA
Description: Dihydrolipoamide succinyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity 0.0197121876070221 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle