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Protein Overview: nmt-1

General Information:
Name(s) found: nmt-1 / CE31611 [WormBase]
Description(s) found:
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  • WBGene00020549 locus:nmt-1 Glycylpeptide N-tetradecanoyltransferase status:Confirmed UniProt:G8JY05 protein_id:CCD63184.1 [WormBase]
  • gi|25148859|ref|NP_741171.1| N-Myristoyl Transferase homolog family member (nmt-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|22532795|gb|AAM97952.1| Hypothetical protein T17E9.2c [Caenorhabditis elegans] [NCBI NR]
  • [wormpep88.fasta]
  • CE31611 WBGene00020549 status:Partially_confirmed TR:Q8MPX2 protein_id:AAM97952.1 [wormpep150.fasta]
  • 31611 WBGene00020549 status:Partially_confirmed TR:Q8MPX2 protein_id:AAM97952.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • n-myristoyltransferase (46.2 kD) (3H204) [Caenorhabditis elegans]gi|22532795|gb|AAM97952.1| Hypothetical protein T17E9.2c [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • status:Partially_confirmed TR:Q8MPX2 protein_id:AAM97952.1 [wormpep115.fasta.reversed]
  • CE31611 WBGene00020549 locus:nmt-1 status:Confirmed UniProt:Q8MPX2_CAEEL protein_id:AAM97952.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE31611 WBGene00020549 locus:nmt-1 status:Confirmed UniProt:Q8MPX2_CAEEL protein_id:AAM97952.1| [wormORF-contam.fasta]
  • T17E9.2c [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein T17E9.2c [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE31611 WBGene00020549 locus:nmt-1 status:Confirmed TR:Q8MPX2 protein_id:AAM97952.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE31611 WBGene00020549 locus:nmt-1 status:Confirmed UniProt:Q8MPX2 protein_id:AAM97952.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE31611 WBGene00020549 locus:nmt-1 status:Confirmed UniProt:G8JY05 protein_id:CCD63184.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
    • Organism: Caenorhabditis elegans
    Length: 403 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    N-terminal protein myristoylation [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: glycylpeptide N-tetradecanoyltransferase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNIPTAPRD MDEARSKSFQ FWSTQPVPQM DETVPADVNC AIEENIALDK VRAEPFSLPA  60
   61 GFRWSNVDLS DEEQLNELYN LLTRNYVEDD DSMFRFDYSA DFLKWALQVP GFRPEWHCGV 120
  121 RADSNNRLLA FIGAVPQTVR VYDKTVNMVE INFLCVHKNL RSRRVAPVLI REITRRVNVT 180
  181 GIFQAAFTAG IVIPKPVSVC RYYHRSLNPR KLIDVRFSHL SAKMTMARTI KLYKLPEETA 240
  241 TRNLREMKST DVPQVFKLLT TSLKQYSLAP VYNSEEELAH ALVPKKGVVY SYVAENQNGK 300
  301 ITDFVSFYSL PSTVMGHTTH KTIYAAYLYY YVAGSVTPKQ LINDSLILAN REKFDVFNAL 360
  361 DLMHNEKIFS DLKFGKGDGN LQYYLYNWKC ADMKPSQIGL VLQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..403] PSI-BLAST 1000.0 Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • N-acyltransferase activity
    		•  5.20638659012287 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  4.84873027228137 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  4.76900479797874 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  4.76900479797874 bayes_pls_golite062009
  • acyltransferase activity
    		•  4.72881921515185 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  4.70793039001114 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  4.69837915971204 bayes_pls_golite062009
  • acetyltransferase activity
    		•  4.61906868269668 bayes_pls_golite062009
  • glycylpeptide N-tetradecanoyltransferase activity
    		•  3.97737934696287 bayes_pls_golite062009
  • myristoyltransferase activity
    		•  3.97737934696287 bayes_pls_golite062009
  • transferase activity
    		•  3.5778020729894 bayes_pls_golite062009
    		• 2.25529786324762 bayes_pls_golite062009
  • catalytic activity
    		•  1.97933499002461 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.862184823552605 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.80295531895447 bayes_pls_golite062009
  • binding
    		•  0.585485465374786 bayes_pls_golite062009
  • transcription factor binding
    		•  0.19149008165837 bayes_pls_golite062009
  • protein binding
    		•  0.075825416385311 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle