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Protein Overview: aak-2

General Information:
Name(s) found: aak-2 / CE31222 [WormBase]
Description(s) found:
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  • WBGene00020142 locus:aak-2 5'-AMP-activated protein kinase catalytic subunit alpha-2 status:Confirmed UniProt:Q95ZQ4 protein_id:CCD68833.1 [WormBase]
  • gi|37993689|gb|AAR06928.1| AMP-activated protein kinase alpha subunit 1 [Caenorhabditis elegans] [NCBI NR]
  • gi|25152839|ref|NP_510711.2| AMP-Activated Kinase family member (aak-2) [Caenorhabditis elegans] [NCBI NR]
  • gi|21629469|gb|AAM69095.1|U58726_1 Amp-activated kinase protein 2, isoform a [Caenorhabditis elegans] [NCBI NR]
  • [wormpep88.fasta]
  • CE31222 WBGene00020142 locus:aak-2 ser\/thr-protein kinase status:Confirmed TR:Q22068 protein_id:AAM69095.1 [wormpep150.fasta]
  • 31222 WBGene00020142 ser\/thr-protein kinase status:Confirmed TR:Q22068 protein_id:AAM69095.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • protein kinase (70.2 kD) (XR417) [Caenorhabditis elegans]gi|37993689|gb|AAR06928.1| AMP-activated protein kinase alpha subunit 1 [Caenorhabditis elegans]gi|21629469|gb|AAM69095.1| Hypothetical protein T01C8.1a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE31222 WBGene00020142 ser\/thr-protein kinase status:Confirmed TR:Q22068 protein_id:AAM69095.1 [wormpep132.fasta]
  • 31222 WBGene00020142 locus:aak-2 ser\/thr-protein kinase status:Confirmed TR:Q22068 protein_id:AAM69095.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • ser\/thr-protein kinase status:Confirmed TR:Q22068 protein_id:AAM69095.1 [wormpep115.fasta.reversed]
  • CE31222 WBGene00020142 locus:aak-2 ser\/thr-protein kinase status:Confirmed UniProt:Q95ZQ4 protein_id:AAM69095.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE31222 WBGene00020142 locus:aak-2 ser\/thr-protein kinase status:Confirmed UniProt:Q95ZQ4 protein_id:AAM69095.1| [wormORF-contam.fasta]
  • CE31222 WBGene00020142 locus:aak-2 ser\/thr-protein kinase status:Confirmed SW:Q95ZQ4 protein_id:AAM69095.1 [wormpep160-contam.fasta]
  • AMP-Activated Kinase family member (aak-2) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Amp-activated kinase protein 2, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • AMP-activated protein kinase alpha subunit 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE31222 WBGene00020142 locus:aak-2 ser\/thr-protein kinase status:Confirmed UniProt:Q95ZQ4 protein_id:CCD68833.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE31222 WBGene00020142 locus:aak-2 status:Confirmed UniProt:Q95ZQ4 protein_id:CCD68833.1 5'-AMP-activated protein kinase catalytic subunit alpha-2 [wormpep246-ecoli-contam.fasta]
  • Isoform of Q95ZQ4, Isoform a of 5'-AMP-activated protein kinase catalytic subunit alpha-2 OS=Caenorhabditis elegans GN=aak-2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 624 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: signal transduction [IEALink to PubMed article]
    determination of adult lifespan [IMPLink to PubMed article]
    protein amino acid phosphorylation [IDALink to PubMed article][IEALink to PubMed article]
    Molecular Function: magnesium ion binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    non-membrane spanning protein tyrosine kinase activity [IEALink to PubMed article]
    protein kinase activity [IDALink to PubMed article][IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSHQDRDRD RKEDGGGDGT EMKSKSRSQP SGLNRVKNLS RKLSAKSRKE RKDRDSTDNS  60
   61 SKMSSPGGET STKQQQELKA QIKIGHYILK ETLGVGTFGK VKVGIHETTQ YKVAVKILNR 120
  121 QKIKSLDVVG KIRREIQNLS LFRHPHIIRL YQVISTPSDI FMIMEHVSGG ELFDYIVKHG 180
  181 RLKTAEARRF FQQIISGVDY CHRHMVVHRD LKPENLLLDE QNNVKIADFG LSNIMTDGDF 240
  241 LRTSCGSPNY AAPEVISGKL YAGPEVDVWS CGVILYALLC GTLPFDDEHV PSLFRKIKSG 300
  301 VFPTPDFLER PIVNLLHHML CVDPMKRATI KDVIAHEWFQ KDLPNYLFPP INESEASIVD 360
  361 IEAVREVTER YHVAEEEVTS ALLGDDPHHH LSIAYNLIVD NKRIADETAK LSIEEFYQVT 420
  421 PNKGPGPVHR HPERIAASVS SKITPTLDNT EASGANRNKR AKWHLGIRSQ SRPEDIMFEV 480
  481 FRAMKQLDME WKVLNPYHVI VRRKPDAPAA DPPKMSLQLY QVDQRSYLLD FKSLADEESG 540
  541 SASASSSRHA SMSMPQKPAG IRGTRTSSMP QAMSMEASIE KMEVHDFSDM SCDVTPPPSP 600
  601 GGAKLSQTMQ FFEICAALIG TLAR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..350] PSI-BLAST 81.522879 No description for 2h6dA was found.
    2 View Details [351..430] deduced N/A No confident structure predictions are available.
    3 View Details [431..624] PSI-BLAST 18.045757 No description for 2v8qA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle