Protein Overview: abl-1

General Information:
Name(s) found:	abl-1 / CE31571 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00000018 locus:abl-1 Tyrosine-protein kinase abl-1 status:Partially_confirmed UniProt:P03949 protein_id:CAB60296.2 [WormBase] gi\|25147108\|ref\|NP_509777.2\| related to oncogene ABL family member (abl-1) [Caenorhabditis elegans] [NCBI NR] gi\|22265850\|emb\|CAB60296.2\| C. elegans protein M79.1b, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] [wormpep88.fasta] CE31571 WBGene00000018 locus:abl-1 status:Partially_confirmed SW:P03949 protein_id:CAB60296.2 [wormpep150.fasta] 31571 WBGene00000018 locus:abl-1 status:Partially_confirmed SW:P03949 protein_id:CAB60296.2 [wormpep130-phg-ecoli-orf-rand.fasta] related to oncogene ABL (abl-1) [Caenorhabditis elegans]gi\|22265850\|emb\|CAB60296.2\| Hypothetical protein M79.1b [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] locus:abl-1 status:Partially_confirmed SW:P03949 protein_id:CAB60296.2 [wormpep115.fasta.reversed] CE31571 WBGene00000018 locus:abl-1 status:Partially_confirmed UniProt:P03949 protein_id:CAB60296.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE31571 WBGene00000018 locus:abl-1 status:Partially_confirmed UniProt:P03949 protein_id:CAB60296.2\| [wormORF-contam.fasta] related to oncogene ABL family member (abl-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] Hypothetical protein M79.1b [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE31571 WBGene00000018 locus:abl-1 status:Partially_confirmed UniProt:P03949 protein_id:CAB60296.2 Tyrosine-protein kinase abl-1 [wormpep246-ecoli-contam.fasta] Isoform of P03949, Isoform b of Tyrosine-protein kinase abl-1 OS=Caenorhabditis elegans GN=abl-1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	1214 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA]
Biological Process:	DNA damage checkpoint [IGI] negative regulation of DNA damage response, signal transduction by p53 class mediator [IGI][IMP] signal transduction [IEA] negative regulation of apoptosis [IGI][IMP] protein amino acid phosphorylation [IEA] response to ionizing radiation [IMP]
Molecular Function:	ATP binding [IEA] protein tyrosine kinase activity [IEA] non-membrane spanning protein tyrosine kinase activity [IEA] protein kinase activity [IEA] protein serine/threonine kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGHSHSTGKE INDNELFTCE DPVFDQPVAS PKSEISSKLA EEIERSKSPL ILEMFRPTFD  60
   61 TFRPPNSDSS TFRGSQSRED LVACSSMNSV NNVHDMNTVS SSSSSSAPLF VALYDFHGVG 120
  121 EEQLSLRKGD QVRILGYNKN NEWCEARLYS TRKNDASNQR RLGEIGWVPS NFIAPYNSLD 180
  181 KYTWYHGKIS RSDSEAILGS GITGSFLVRE SETSIGQYTI SVRHDGRVFH YRINVDNTEK 240
  241 MFITQEVKFR TLGELVHHHS VHADGLICLL MYPASKKDKG RGLFSLSPNA PDEWELDRSE 300
  301 IIMHNKLGGG QYGDVYEGYW KRHDCTIAVK ALKEDAMPLH EFLAEAAIMK DLHHKNLVRL 360
  361 LGVCTHEAPF YIITEFMCNG NLLEYLRRTD KSLLPPIILV QMASQIASGM SYLEARHFIH 420
  421 RDLAARNCLV SEHNIVKIAD FGLARFMKED TYTAHAGAKF PIKWTAPEGL AFNTFSSKSD 480
  481 VWAFGVLLWE IATYGMAPYP GVELSNVYGL LENGFRMDGP QGCPPSVYRL MLQCWNWSPS 540
  541 DRPRFRDIHF NLENLISSNS LNDEVQKQLK KNNDKKLESD KRRSNVRERS DSKSRHSSHH 600
  601 DRDRDRESLH SRNSNPEIPN RSFIRTDDSV SFFNPSTTSK VTSFRAQGPP FPPPPQQNTK 660
  661 PKLLKSVLNS NARHASEEFE RNEQDDVVPL AEKNVRKAVT RLGGTMPKGQ RIDAYLDSMR 720
  721 RVDSWKESTD ADNEGAGSSS LSRTVSNDSL DTLPLPDSMN SSTYVKMHPA SGENVFLRQI 780
  781 RSKLKKRSET PELDHIDSDT ADETTKSEKS PFGSLNKSSI KYPIKNAPEF SENHSRVSPV 840
  841 PVPPSRNASV SVRPDSKAED SSDETTKDVG MWGPKHAVTR KIEIVKNDSY PNVEGELKAK 900
  901 IRNLRHVPKE ESNTSSQEDL PLDATDNTND SIIVIPRDEK AKVRQLVTQK VSPLQHHRPF 960
  961 SLQCPNNSTS SAISHSEHAD SSETSSLSGV YEERMKPELP RKRSNGDTKV VPVTWIINGE1020
 1021 KEPNGMARTK SLRDITSKFE QLGTASTIES KIEEAVPYRE HALEKKGTSK RFSMLEGSNE1080
 1081 LKHVVPPRKN RNQDESGSID EEPVSKDMIV SLLKVIQKEF VNLFNLASSE ITDEKLQQFV1140
 1141 IMADNVQKLH STCSVYAEQI SPHSKFRFKE LLSQLEIYNR QIKFSHNPRA KPVDDKLKMA1200
 1201 FQDCFDQIMR LVDR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: abl-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: