Protein Overview: abl-1

General Information:
Name(s) found:	abl-1 / CE31570 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00000018 locus:abl-1 Tyrosine-protein kinase abl-1 status:Partially_confirmed UniProt:P03949 protein_id:CAA90691.2 [WormBase] gi\|27808642\|sp\|P03949.4\|ABL1_CAEEL RecName: Full=Tyrosine-protein kinase abl-1 [NCBI NR] gi\|25147104\|ref\|NP_509778.2\| related to oncogene ABL family member (abl-1) [Caenorhabditis elegans] [NCBI NR] gi\|22265851\|emb\|CAA90691.2\| C. elegans protein M79.1a, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] Tyrosine-protein kinase abl-1 OS=Caenorhabditis elegans GN=abl-1 PE=1 SV=4 [Swiss-Prot] [wormpep88.fasta] CE31570 WBGene00000018 locus:abl-1 Src homology domain 2, Src homology domain 3, protein tyrosine kinase (ABL subfamily) status:Partially_confirmed SW:P03949 protein_id:CAA90691.2 [wormpep150.fasta] 31570 WBGene00000018 locus:abl-1 Src homology domain 2, Src homology domain 3, protein tyrosine kinase (ABL subfamily) status:Partially_confirmed SW:P03949 protein_id:CAA90691.2 [wormpep130-phg-ecoli-orf-rand.fasta] related to oncogene ABL (138.3 kD) (abl-1) [Caenorhabditis elegans]gi\|22265851\|emb\|CAA90691.2\| Hypothetical protein M79.1a [Caenorhabditis elegans]gi\|27808642\|sp\|P03949\|ABL1_CAEEL Tyrosine-protein kinase abl-1 [nrdb_11152004_Chlamydomonas] locus:abl-1 Src homology domain 2, Src homology domain 3, protein tyrosine kinase (ABL subfamily) status:Partially_confirmed SW:P03949 protein_id:CAA90691.2 [wormpep115.fasta.reversed] CE31570 WBGene00000018 locus:abl-1 Src homology domain 2, Src homology domain 3, protein tyrosine kinase (ABL subfamily) status:Partially_confirmed UniProt:P03949 protein_id:CAA90691.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE31570 WBGene00000018 locus:abl-1 Src homology domain 2, Src homology domain 3, protein tyrosine kinase (ABL subfamily) status:Partially_confirmed UniProt:P03949 protein_id:CAA90691.2\| [wormORF-contam.fasta] Hypothetical protein M79.1a [Caenorhabditis elegans] [nr-271106-contam.fasta] related to oncogene ABL family member (abl-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] Tyrosine-protein kinase abl-1 [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE31570 WBGene00000018 locus:abl-1 status:Partially_confirmed UniProt:P03949 protein_id:CAA90691.2 Tyrosine-protein kinase abl-1 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	1224 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA]
Biological Process:	DNA damage checkpoint [IGI] negative regulation of DNA damage response, signal transduction by p53 class mediator [IGI][IMP] signal transduction [IEA] negative regulation of apoptosis [IGI][IMP] protein amino acid phosphorylation [IEA] response to ionizing radiation [IMP]
Molecular Function:	ATP binding [IEA] protein tyrosine kinase activity [IEA] non-membrane spanning protein tyrosine kinase activity [IEA] protein kinase activity [IEA] protein serine/threonine kinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGHSHSTGKE INDNELFTCE DPVFDQPVAS PKSEISSKLA EEIERSKSPL ILEVSPRTPD  60
   61 SVQMFRPTFD TFRPPNSDSS TFRGSQSRED LVACSSMNSV NNVHDMNTVS SSSSSSAPLF 120
  121 VALYDFHGVG EEQLSLRKGD QVRILGYNKN NEWCEARLYS TRKNDASNQR RLGEIGWVPS 180
  181 NFIAPYNSLD KYTWYHGKIS RSDSEAILGS GITGSFLVRE SETSIGQYTI SVRHDGRVFH 240
  241 YRINVDNTEK MFITQEVKFR TLGELVHHHS VHADGLICLL MYPASKKDKG RGLFSLSPNA 300
  301 PDEWELDRSE IIMHNKLGGG QYGDVYEGYW KRHDCTIAVK ALKEDAMPLH EFLAEAAIMK 360
  361 DLHHKNLVRL LGVCTHEAPF YIITEFMCNG NLLEYLRRTD KSLLPPIILV QMASQIASGM 420
  421 SYLEARHFIH RDLAARNCLV SEHNIVKIAD FGLARFMKED TYTAHAGAKF PIKWTAPEGL 480
  481 AFNTFSSKSD VWAFGVLLWE IATYGMAPYP GVELSNVYGL LENGFRMDGP QGCPPSVYRL 540
  541 MLQCWNWSPS DRPRFRDIHF NLENLISSNS LNDEVQKQLK KNNDKKLESD KRRSNVRERS 600
  601 DSKSRHSSHH DRDRDRESLH SRNSNPEIPN RSFIRTDDSV SFFNPSTTSK VTSFRAQGPP 660
  661 FPPPPQQNTK PKLLKSVLNS NARHASEEFE RNEQDDVVPL AEKNVRKAVT RLGGTMPKGQ 720
  721 RIDAYLDSMR RVDSWKESTD ADNEGAGSSS LSRTVSNDSL DTLPLPDSMN SSTYVKMHPA 780
  781 SGENVFLRQI RSKLKKRSET PELDHIDSDT ADETTKSEKS PFGSLNKSSI KYPIKNAPEF 840
  841 SENHSRVSPV PVPPSRNASV SVRPDSKAED SSDETTKDVG MWGPKHAVTR KIEIVKNDSY 900
  901 PNVEGELKAK IRNLRHVPKE ESNTSSQEDL PLDATDNTND SIIVIPRDEK AKVRQLVTQK 960
  961 VSPLQHHRPF SLQCPNNSTS SAISHSEHAD SSETSSLSGV YEERMKPELP RKRSNGDTKV1020
 1021 VPVTWIINGE KEPNGMARTK SLRDITSKFE QLGTASTIES KIEEAVPYRE HALEKKGTSK1080
 1081 RFSMLEGSNE LKHVVPPRKN RNQDESGSID EEPVSKDMIV SLLKVIQKEF VNLFNLASSE1140
 1141 ITDEKLQQFV IMADNVQKLH STCSVYAEQI SPHSKFRFKE LLSQLEIYNR QIKFSHNPRA1200
 1201 KPVDDKLKMA FQDCFDQIMR LVDR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: abl-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: