Protein Overview: CE31971

General Information:
Name(s) found:	CE31971 [WormBase]
Description(s) found: Found 17 descriptions. SHOW ALL	WBGene00010794 locus:dld-1 Dihydrolipoyl dehydrogenase, mitochondrial status:Confirmed UniProt:O17953 protein_id:CAB05249.2 [WormBase]
Organism:	Caenorhabditis elegans
Length:	495 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IEA]
Biological Process:	electron transport [IEA] glutamate biosynthetic process [IEA] nematode larval development [IMP ] removal of superoxide radicals [IEA] glutathione metabolic process [IEA] embryonic development ending in birth or egg hatching [IMP ] cell redox homeostasis [IEA] growth [IMP ] detoxification of mercury ion [IEA]
Molecular Function:	disulfide oxidoreductase activity [IEA] NADP or NADPH binding [IEA] oxidoreductase activity [IEA] FAD binding [IEA] oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [IEA] mercury ion binding [IEA] mercury (II) reductase activity [IEA] thioredoxin-disulfide reductase activity [IEA] glutathione-disulfide reductase activity [IEA] dihydrolipoyl dehydrogenase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSRTTQLP FAKRQFFQVL ARNYSNTQDA DLVVIGGGPG GYVAAIKAAQ LGMKTVCVEK  60
   61 NATLGGTCLN VGCIPSKALL NNSHYLHMAQ HDFAARGIDC TASLNLPKMM EAKSNSVKQL 120
  121 TGGIKQLFKA NKVGHVEGFA TIVGPNTVQA KKNDGSVETI NARNILIASG SEVTPFPGIT 180
  181 IDEKQIVSST GALSLGQVPK KMVVIGAGVI GLELGSVWQR LGAEVTAVEF LGHVGGMGID 240
  241 GEVSKNFQRS LTKQGFKFLL NTKVMGASQN GSTITVEVEG AKDGKKQTLE CDTLLVSVGR 300
  301 RPYTEGLGLS NVQIDLDNRG RVPVNERFQT KVPSIFAIGD VIEGPMLAHK AEDEGILCVE 360
  361 GIAGGPVHID YNCVPSVVYT HPEVAWVGKA EEQLKQEGVA YKIGKFPFVA NSRAKTNNDQ 420
  421 EGFVKVLADK QTDRMLGVHI IGPNAGEMIA EATLAMEYGA SAEDVARVCH PHPTLSEAFR 480
  481 EANLAAYCGK AINNV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-1	hcp1 IP from december2004	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..495]	PSI-BLAST	111.0	The crystal structure of dihydrolipoamide dehydrogenase and dihydrolipoamide dehydrogenase-binding protein (didomain) subcomplex of human pyruvate dehydrogenase complex.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: CE31971

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: