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Protein Overview: ife-1

General Information:
Name(s) found: ife-1 / CE31809 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00002059 locus:ife-1 Eukaryotic translation initiation factor 4E-1 status:Confirmed UniProt:O45551 protein_id:CAB04454.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 212 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article][IEALink to PubMed article]
    P granule [IDALink to PubMed article]
    Biological Process: translational initiation [IEALink to PubMed article]
    Molecular Function: translation initiation factor activity [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTETEQTTAP IYPLKRNWTW WYLNDERNKS WEDRLKKVYT FNTVSEFWAL YDAIRPPSGL  60
   61 NALCDYNVFR DDIQPMWEVP ENSNGGRWLI VIDKGKTPEM VDAIWLEILM ALVGEQFGKD 120
  121 MESICGLVCN VRGKGSKISV WTKDCNDDET NMRIGVVLKE KLMAASKDHS KPLFDVIRYE 180
  181 DHESCQKKTS SVVKAKLSLH SSDAPVAEKS AV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..212] PSI-BLAST 69.221849 Translation initiation factor eIF4e

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  12.6022960879923 bayes_pls_golite062009
  • RNA cap binding
    		•  8.70938037002519 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  7.91586572659635 bayes_pls_golite062009
  • translation regulator activity
    		•  7.87578736455963 bayes_pls_golite062009
  • RNA binding
    		•  4.73187299490341 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.46353214508261 bayes_pls_golite062009
  • binding
    		•  2.88787215275737 bayes_pls_golite062009
  • protein binding
    		•  0.873044754151905 bayes_pls_golite062009
  • RNA 7-methylguanosine cap binding
    		•  0.544036568660606 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle