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Protein Overview: ppk-1

General Information:
Name(s) found: ppk-1 / CE30541 [WormBase]
Description(s) found:
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  • WBGene00004087 locus:ppk-1 status:Confirmed UniProt:O01759 protein_id:CCD65437.1 [WormBase]
  • gi|25150133|ref|NP_491576.2| PIP Kinase family member (ppk-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|20198835|gb|AAB54130.2| Pip kinase protein 1 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep79.fasta]
  • CE30541 WBGene00004087 locus:ppk-1 status:Partially_confirmed TR:O01759 protein_id:AAB54130.2 [wormpep150.fasta]
  • 30541 WBGene00004087 locus:ppk-1 status:Partially_confirmed TR:O01759 protein_id:AAB54130.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • phosphatidylinositol phosphate kinase, phosphatidylinositol phosphate kinase PPK-1 (68.6 kD) (ppk-1) [Caenorhabditis elegans]gi|20198835|gb|AAB54130.2| Pip kinase protein 1 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:ppk-1 status:Partially_confirmed TR:O01759 protein_id:AAB54130.2 [wormpep115.fasta.reversed]
  • CE30541 locus:ppk-1 status:Partially_confirmed [wormpep80.hongbin]
  • CE30541 WBGene00004087 locus:ppk-1 status:Partially_confirmed UniProt:O01759_CAEEL protein_id:AAB54130.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE30541 WBGene00004087 locus:ppk-1 status:Partially_confirmed UniProt:O01759_CAEEL protein_id:AAB54130.2| [wormORF-contam.fasta]
  • Pip kinase protein 1 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • PIP Kinase family member (ppk-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE30541 WBGene00004087 locus:ppk-1 status:Partially_confirmed UniProt:O01759 protein_id:AAB54130.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE30541 WBGene00004087 locus:ppk-1 status:Confirmed UniProt:O01759 protein_id:CCD65437.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • PIP Kinase OS=Caenorhabditis elegans GN=ppk-1 PE=1 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 611 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    phosphatidylinositol metabolic process [IEALink to PubMed article]
    growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Molecular Function: phosphatidylinositol phosphate kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASRSTTIAF KRTGDAEEEG KPPEQGDDNG EKQEAPILRP DNEAKDLPLN TLGNQTSREQ  60
   61 QNTKEKLGHR RIDEQGGVSY KKVPTNALMQ AIQLGISNSI GSLASLPNRD VLLQDFEKVD 120
  121 IVAFPAAGST ITPSHSFGDF RFRTYAPIAF RYFRNLFHIK PADFLRSICT EPLKELSNAG 180
  181 ASGSIFYVSQ DDQFIIKTVQ HKEADFLQKL LPGYYMNLNQ NPRTLLPKFF GLFCYQSLGK 240
  241 NIRLLVMNNL LPQTVTMHEK YDMKGSTYKR MANKAERAKP HPTLKDLDFL ENHKDGIFID 300
  301 PTALEALMKS ISRDCLVMES FKIMDYSLLV GIHNVELGIK ERAEQNRESH PAPSTSSDTF 360
  361 SGEKAENHKV LQEKFSVWDT GDGDVPHGGV PARNSNGDRL VLYLGIIDIL QNYRLLKKME 420
  421 HTWKAILHDG DTISVHNPNF YASRFLTFMT EKVFKKGTAL KQSPSRRRML KGNSHEDDSI 480
  481 VIVSSGHRQH RESERDGLNM TVTVTDGAST STPRGDTTQF GSQTARESTR LYNRDSTGIN 540
  541 EDRANSAREP PSSMSRVPLR RSYRDAGQAM SADKKEKKVE RLFAQSKPTD EKVPEEQEEA 600
  601 EEIVSGDTPV A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..456] PSI-BLAST 106.0 Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta
    2 View Details [457..611] MSA 13.142997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • inositol or phosphatidylinositol kinase activity
    		•  4.31726963575315 bayes_pls_golite062009
  • lipid kinase activity
    		•  3.63026201392483 bayes_pls_golite062009
  • phosphatidylinositol phosphate kinase activity
    		•  3.29315211323714 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.8512866333787 bayes_pls_golite062009
  • kinase activity
    		•  2.68971389233526 bayes_pls_golite062009
  • 1-phosphatidylinositol-4-phosphate 5-kinase activity
    		•  2.65186975336776 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.31077377326314 bayes_pls_golite062009
  • catalytic activity
    		•  1.87792712964225 bayes_pls_golite062009
  • binding
    		•  1.23659721062619 bayes_pls_golite062009
  • transferase activity
    		•  1.20817067352467 bayes_pls_golite062009
  • ligase activity
    		•  0.435608917599349 bayes_pls_golite062009
  • protein kinase activity
    		•  0.422676745032915 bayes_pls_golite062009
  • protein binding
    		•  0.382966234080422 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.189737258618863 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.14608192065514 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle