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View Structure Prediction Details

Protein: ppk-1
Organism: Caenorhabditis elegans
Length: 611 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ppk-1.

Description E-value Query
Range
Subject
Range
gi|187029460, gi... - gi|39589697|emb|CAE66932.1| Hypothetical protein CBG12324 [Caenorhabditis briggsae], gi|187029460|em...
gi|157746477 - gi|157746477|ref|XP_001668334.1| Hypothetical protein CBG12324 [Caenorhabditis briggsae AF16]
567.0 [0..1] [611..1]

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Predicted Domain #1
Region A:
Residues: [1-456]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASRSTTIAF KRTGDAEEEG KPPEQGDDNG EKQEAPILRP DNEAKDLPLN TLGNQTSREQ  60
   61 QNTKEKLGHR RIDEQGGVSY KKVPTNALMQ AIQLGISNSI GSLASLPNRD VLLQDFEKVD 120
  121 IVAFPAAGST ITPSHSFGDF RFRTYAPIAF RYFRNLFHIK PADFLRSICT EPLKELSNAG 180
  181 ASGSIFYVSQ DDQFIIKTVQ HKEADFLQKL LPGYYMNLNQ NPRTLLPKFF GLFCYQSLGK 240
  241 NIRLLVMNNL LPQTVTMHEK YDMKGSTYKR MANKAERAKP HPTLKDLDFL ENHKDGIFID 300
  301 PTALEALMKS ISRDCLVMES FKIMDYSLLV GIHNVELGIK ERAEQNRESH PAPSTSSDTF 360
  361 SGEKAENHKV LQEKFSVWDT GDGDVPHGGV PARNSNGDRL VLYLGIIDIL QNYRLLKKME 420
  421 HTWKAILHDG DTISVHNPNF YASRFLTFMT EKVFKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 106.0
Match: 1bo1A
Description: Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
inositol or phosphatidylinositol kinase activity 4.31726963575315 bayes_pls_golite062009
lipid kinase activity 3.63026201392483 bayes_pls_golite062009
phosphatidylinositol phosphate kinase activity 3.29315211323714 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 2.8512866333787 bayes_pls_golite062009
kinase activity 2.68971389233526 bayes_pls_golite062009
1-phosphatidylinositol-4-phosphate 5-kinase activity 2.65186975336776 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.31077377326314 bayes_pls_golite062009
catalytic activity 1.87792712964225 bayes_pls_golite062009
binding 1.23659721062619 bayes_pls_golite062009
transferase activity 1.20817067352467 bayes_pls_golite062009
ligase activity 0.435608917599349 bayes_pls_golite062009
protein kinase activity 0.422676745032915 bayes_pls_golite062009
protein binding 0.382966234080422 bayes_pls_golite062009
protein serine/threonine kinase activity 0.189737258618863 bayes_pls_golite062009
acid-amino acid ligase activity 0.14608192065514 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [457-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTALKQSPSR RRMLKGNSHE DDSIVIVSSG HRQHRESERD GLNMTVTVTD GASTSTPRGD  60
   61 TTQFGSQTAR ESTRLYNRDS TGINEDRANS AREPPSSMSR VPLRRSYRDA GQAMSADKKE 120
  121 KKVERLFAQS KPTDEKVPEE QEEAEEIVSG DTPVA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle