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Protein Overview: ula-1

General Information:
Name(s) found: ula-1 / CE29678 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00006735 locus:ula-1 NEDD8-activating enzyme E1 regulatory subunit status:Confirmed UniProt:Q18217 protein_id:CCD65733.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 541 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: locomotory behavior [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    gamete generation [IMPLink to PubMed articleLink to PubMed article]
    Mo-molybdopterin cofactor biosynthetic process [IEALink to PubMed article]
    Molecular Function: catalytic activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPFDPSTRY DRQVRLWGEE GQASIGSTSA CVLGSDSLAT EILKSLVLAG VQSFYVVDDA  60
   61 KVEQADIGQN FFLHADDIGR SRAEATLEKL TELNPSVSGS ASSQPPTALA MEDVEKLTTF 120
  121 SVVVAANQNE EIDTTFAKVL YNIRVPFICI KTFGLIGTIR ICIKEHTIAN SHEENPRPDL 180
  181 RLDAPFSKLI EMINETNLDE MTLEQLRHTP YILLHFKALE VFRKQRNDPE AFPSTTAERK 240
  241 ELQAILMSFR RSSEESGTKD SENFDEAKAA VIRAFQRTTI GSSVKSILSS PQCSTSTRPF 300
  301 WLICEALRRF VTENNNLLPL RGTLPDMTSD SSRYTRLATL FHEKALSDAQ EVLRLTREVE 360
  361 KERGVGDVIS DDVCYRFCKN ADRIRVQYGD VLDYNEETKA IVEKIRESNI DEETRNQKVD 420
  421 EATWMLLMRA VGRFQKEKGR YPGTNGVPVS IDAQDLKKRV EVLIREALKD EQDFTSISNK 480
  481 VTDTAIAEIC RFGAAELHVI SSYVGGIAAQ EIIKLATNQY VPIDNTFIFD GHTQESATFK 540
  541 F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..541] PSI-BLAST 97.221849 No description for 2nvuA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • small protein activating enzyme activity
    		•  5.883593664369 bayes_pls_golite062009
  • NEDD8 activating enzyme activity
    		•  4.6334061288737 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  1.84216910649062 bayes_pls_golite062009
  • binding
    		•  1.66028321721112 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.63522698057369 bayes_pls_golite062009
  • protein binding
    		•  1.40907622346701 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.31244773198273 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  1.27535252106053 bayes_pls_golite062009
  • catalytic activity
    		•  1.22201444897049 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  1.11310449351601 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.995905648772847 bayes_pls_golite062009
  • transferase activity
    		•  0.680338489823338 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.302798969355962 bayes_pls_golite062009
  • URM1 activating enzyme activity
    		•  0.207228630005671 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle