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Protein Overview: ubc-6

General Information:
Name(s) found: ubc-6 / CE29241 [WormBase]
Description(s) found:
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  • WBGene00006703 locus:ubc-6 status:Confirmed UniProt:Q18931 protein_id:CCD68333.1 [WormBase]
  • gi|17532649|ref|NP_495566.1| UBiquitin Conjugating enzyme family member (ubc-6) [Caenorhabditis elegans] [NCBI NR]
  • gi|15617759|gb|AAB93334.2| Ubiquitin conjugating enzyme protein 6, isoform a [Caenorhabditis elegans] [NCBI NR]
  • gi|115532480|ref|NP_001040755.1| UBiquitin Conjugating enzyme family member (ubc-6) [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE29241 WBGene00006703 locus:ubc-6 Ubiquitin-conjugating enzyme status:Confirmed TR:Q18931 protein_id:AAB93334.2 [wormpep150.fasta]
  • 29241 WBGene00006703 locus:ubc-6 Ubiquitin-conjugating enzyme status:Confirmed TR:Q18931 protein_id:AAB93334.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • ubiquitin conjugating enzyme (35.3 kD) (ubc-6) [Caenorhabditis elegans]gi|15617759|gb|AAB93334.2| Ubiquitin conjugating enzyme protein 6 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • locus:ubc-6 Ubiquitin-conjugating enzyme status:Confirmed TR:Q18931 protein_id:AAB93334.2 [wormpep115.fasta.reversed]
  • CE29241 Ubiquitin-conjugating enzyme status:Partially_confirmed TR:Q18931 protein_id:AAB93334.2 [wormpep80.hongbin]
  • CE29241 WBGene00006703 locus:ubc-6 Ubiquitin-conjugating enzyme status:Confirmed UniProt:Q18931_CAEEL protein_id:AAB93334.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE29241 WBGene00006703 locus:ubc-6 Ubiquitin-conjugating enzyme status:Confirmed UniProt:Q18931_CAEEL protein_id:AAB93334.2| [wormORF-contam.fasta]
  • CE29241 WBGene00006703 locus:ubc-6 Ubiquitin-conjugating enzyme status:Confirmed [wormpep160-contam.fasta]
  • UBiquitin Conjugating enzyme family member (ubc-6) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Ubiquitin conjugating enzyme protein 6 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE29241 WBGene00006703 locus:ubc-6 Ubiquitin-conjugating enzyme status:Confirmed UniProt:Q18931 protein_id:AAB93334.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE29241 WBGene00006703 locus:ubc-6 Ubiquitin-conjugating enzyme status:Confirmed UniProt:Q18931 protein_id:CCD68333.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE29241 WBGene00006703 locus:ubc-6 status:Confirmed UniProt:Q18931 protein_id:CCD68333.1 [wormpep246-ecoli-contam.fasta]
  • UBiquitin Conjugating enzyme OS=Caenorhabditis elegans GN=ubc-6 PE=1 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 314 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEALink to PubMed article]
    Biological Process: protein modification process [IEALink to PubMed article]
    ubiquitin cycle [IEALink to PubMed article]
    Molecular Function: small conjugating protein ligase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEQYNTKNA GVRRLMKEAM ELRQPTEMYH AQPMEDNLFE WHFTIRGTLG TDFEGGIYHG  60
   61 RIIFPADYPM KPPNLILLTP NGRFELNKKV CLSISGYHPE TWLPSWSIRT ALLALIGFLP 120
  121 STPGGALGSL DYPPKERQRL AKLSCEWKCK ECGCVMKTAL LPITEDGQLK QTEEAKTLAA 180
  181 QLKFQDESVV KKEVEAANNQ KNPTETEPSE ETSSVPTENV EESEEDADER EEGTTVNVNS 240
  241 SEVPDVAQPA VQPIRDPQPL VFQHHAPRLA STNFDYTLLY KIPVIALCFA IFFTLLARRF 300
  301 LVDNLTSPKD GSEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..197] PSI-BLAST 41.045757 Human ubiquitin-conjugating enzyme E2 J2
    2 View Details [198..314] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • small conjugating protein ligase activity
    		•  6.13787067729569 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  6.13342835108038 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  5.20679401190557 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  4.30935997378918 bayes_pls_golite062009
  • ligase activity
    		•  1.28816297541508 bayes_pls_golite062009
  • catalytic activity
    		•  0.891402822028799 bayes_pls_golite062009
  • binding
    		•  0.852142254811421 bayes_pls_golite062009
  • NEDD8 ligase activity
    		•  0.715654744941217 bayes_pls_golite062009
  • protein binding
    		•  0.470754319870613 bayes_pls_golite062009
  • protein kinase activity
    		•  0.0722326952092479 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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    Created and Maintained by: Michael Riffle