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Protein Overview: nhr-46

General Information:
Name(s) found: nhr-46 / CE29227 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00003636 locus:nhr-46 status:Partially_confirmed UniProt:Q95QR3 protein_id:CCD67375.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 395 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCSADNHCDI TNESRNRCRA CRLRNCLEGG MNPKHVREER SKIERMPGNT CTVSAANGVS  60
   61 HSSSAASASP EHKFSFSLST IAPSTSTGSF SSGSQPAPIE STNSSGSEAE VLDRKLIQEN 120
  121 QLTLFMVALE KQTEQLTDDD VKDNDVMGAW SRDITLTFGL QHPQMVIKRL PLKYSCDRIM 180
  181 EAADLYLSWY RSFVFAADWA MGIPEFRVLP LADQTTLFKQ NFMAFGWITF AYKCFELKQH 240
  241 LTGMPLGNGA YIPYNDEDQK KLPERWAQTY GVVCRKLIDL IVKAMIELQI TEEEYCLIKT 300
  301 ISLFQQDCIL SEAGQGICSR MRDRLLDALS AHIEKRYPYH TTSQRMTRAL KISLMLPSFS 360
  361 HIGQVESTLI TQLTAADLHQ LSGVPMEICT AQTTL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] PSI-BLAST 5.09691 Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
    2 View Details [89..395] PSI-BLAST 53.045757 LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.15996699473685 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.46162010671465 bayes_pls_golite062009
  • protein binding
    		•  0.33427459029264 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.15459949087509 bayes_pls_golite062009
  • DNA binding
    		•  0.14395376162921 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle