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Protein Overview: nhr-46

General Information:
Name(s) found: nhr-46 / CE29226 [WormBase]
Description(s) found:
Found 16 descriptions.
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  • WBGene00003636 locus:nhr-46 status:Partially_confirmed UniProt:Q95QR2 protein_id:CCD67374.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 576 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]
    steroid binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELFRSPPQT AMFPTTASSS FVSAALHQQQ SSPSSNLPVI PSPTDMITVT STSPIPITTS  60
   61 ASPPNLPMFL SFPSTSTTTS ILMDTVLAAQ KLNQQQNQQA FNFMVVKQEN GETGRNFMTM 120
  121 KQDALQAITN TVSRNSPPNV IKGERCVGCG SESAIRVHYG ASSCHGCKAF FRRSVFEGRV 180
  181 YMCSADNHCD ITNESRNRCR ACRLRNCLEG GMNPKHVREE RSKIERMPGN TCTVSAANGV 240
  241 SHSSSAASAS PEHKFSFSLS TIAPSTSTGS FSSGSQPAPI ESTNSSGSEA EVLDRKLIQE 300
  301 NQLTLFMVAL EKQTEQLTDD DVKDNDVMGA WSRDITLTFG LQHPQMVIKR LPLKYSCDRI 360
  361 MEAADLYLSW YRSFVFAADW AMGIPEFRVL PLADQTTLFK QNFMAFGWIT FAYKCFELKQ 420
  421 HLTGMPLGNG AYIPYNDEDQ KKLPERWAQT YGVVCRKLID LIVKAMIELQ ITEEEYCLIK 480
  481 TISLFQQDCI LSEAGQGICS RMRDRLLDAL SAHIEKRYPY HTTSQRMTRA LKISLMLPSF 540
  541 SHIGQVESTL ITQLTAADLH QLSGVPMEIC TAQTTL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138] MSA 7.274996 View MSA. No confident structure predictions are available.
    2 View Details [139..261] PSI-BLAST 18.0 No description for 2hanB was found.
    3 View Details [262..576] PSI-BLAST 56.522879 LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.270879137859077 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  1.15996699473685 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.46162010671465 bayes_pls_golite062009
  • protein binding
    		•  0.33427459029264 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.15459949087509 bayes_pls_golite062009
  • DNA binding
    		•  0.14395376162921 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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