Protein Overview: gld-3

General Information:
Name(s) found:	gld-3 / CE28652 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00001597 locus:gld-3 Defective in germ line development protein 3 status:Confirmed UniProt:Q95ZK7 protein_id:CCD65916.1 [WormBase] gi\|17536109\|ref\|NP_495480.1\| defective in Germ Line Development family member (gld-3) [Caenorhabditis elegans] [NCBI NR] gi\|15011799\|gb\|AAK77630.1\|U80954_4 Defective in germ line development protein 3, isoform b [Caenorhabditis elegans] [NCBI NR] [wormpep67.fasta] CE28652 WBGene00001597 locus:gld-3 status:Partially_confirmed TR:Q95ZK6 protein_id:AAK77630.1 [wormpep150.fasta] 28652 WBGene00001597 locus:gld-3 status:Partially_confirmed TR:Q95ZK6 protein_id:AAK77630.1 [wormpep130-phg-ecoli-orf-rand.fasta] bicaudal C like, defective in Germ Line Development GLD-3 (68.5 kD) (gld-3) [Caenorhabditis elegans]gi\|15011799\|gb\|AAK77630.1\| Defective in germ line development protein 3, isoform b [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas] locus:gld-3 status:Partially_confirmed TR:Q95ZK6 protein_id:AAK77630.1 [wormpep115.fasta.reversed] CE28652 status:Partially_confirmed TR:Q95ZK6 protein_id:AAK77630.1 [wormpep80.hongbin] CE28652 WBGene00001597 locus:gld-3 status:Partially_confirmed UniProt:Q95ZK6_CAEEL protein_id:AAK77630.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE28652 WBGene00001597 locus:gld-3 status:Partially_confirmed UniProt:Q95ZK6_CAEEL protein_id:AAK77630.1\| [wormORF-contam.fasta] defective in Germ Line Development family member (gld-3) [Caenorhabditis elegans] [nr-271106-contam.fasta] Defective in germ line development protein 3, isoform b [Caenorhabditis elegans] [nr-271106-contam.fasta] CE28652 WBGene00001597 locus:gld-3 status:Partially_confirmed UniProt:Q95ZK6 protein_id:AAK77630.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE28652 WBGene00001597 locus:gld-3 status:Confirmed UniProt:Q95ZK6 protein_id:CCD65916.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE28652 WBGene00001597 locus:gld-3 status:Confirmed UniProt:Q95ZK7 protein_id:CCD65916.1 [wormbase_c_elegans_ws234_and_mcherry_10-06-2012_reversed.fasta] CE28652 WBGene00001597 locus:gld-3 status:Confirmed UniProt:Q95ZK7 protein_id:CCD65916.1 Defective in germ line development protein 3 [wormpep246-ecoli-contam.fasta]
Organism:	Caenorhabditis elegans
Length:	603 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA] P granule [IDA]
Biological Process:	vulval development [IMP] positive regulation of meiosis [IGI][IMP] feminization of hermaphroditic germ-line [IMP] embryonic development ending in birth or egg hatching [IMP ] spermatogenesis [IMP] regulation of meiosis [IMP ] germ-line stem cell division [IMP] cytokinesis [IMP] gamete generation [IMP ] masculinization of hermaphroditic germ-line [IMP ] positive regulation of multicellular organism growth [IMP] reproduction [IMP] nematode larval development [IMP] negative regulation of binding [IDA] nuclear division [IMP] germ-line sex determination [IMP]
Molecular Function:	protein domain specific binding [IPI] protein binding [IPI] RNA binding [IEA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEQSHEKDH DEAHSYNPFV RSAVEYDADT RLQMAENAAS ARKLFVSSAL KDIIVNPENF  60
   61 YHDFQQSAQM AEDANQRRQV SYNTKREAHI HQLKAQGLPL PSNIPMIEIN PTRVTLNMEF 120
  121 ESQYYSLMTS DNGDHENVAS IMAETNTLIQ LPDRSVGGTT PDPFAQQVTI TGYFGDVDRA 180
  181 RMLMRRNCHF TVFMALSKMK MPLHELQAHV RQNPIQNVEM SFVDAPEKNG IVTTYLRITA 240
  241 REKNQHELIE AAKRLNEILF RESPAPENNF TLHFTLSTYY VDQVLGSSST AQLMPVIERE 300
  301 TTTIISYPCY NNRNETRGNI YEIKVVGNID NVLKARRYIM DLLPISMCFN IKNTDMAEPS 360
  361 RVSDRNIHMI IDESGIILKM TPSVYEPADL LSGEVPLNCA SLRSKEFNIK KLYTAYQKVL 420
  421 SKKFDFIAPQ PNDYDNSIWH HSLPANFLKN FNMPCRGELS DGSNGRRHRS SSIASSRSKH 480
  481 SYMSKGKQFS ESSGGPSRSH TRVSSFSENS STVPIMQFPT PHFAPPMLTP HHHMLKYVYL 540
  541 QQHQQAQTFL KGAAGLHPGT HIMFPPPIIV DGSFGARYSS NIYPFSYIVP QNFNFLNGNF 600
  601 GHL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-2	hcp2 ip from december	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..205]	PSI-BLAST	9.0	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
2	View Details	[206..261]	deduced	N/A	No confident structure predictions are available.
3	View Details	[262..420]	PSI-BLAST	22.0	No description for 2annA was found.
4	View Details	[421..603]	MSA	2.172995	View MSA. No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: gld-3

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: