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Protein Overview: gld-3

General Information:
Name(s) found: gld-3 / CE28652 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00001597 locus:gld-3 Defective in germ line development protein 3 status:Confirmed UniProt:Q95ZK7 protein_id:CCD65916.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 603 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    P granule [IDALink to PubMed article]
    Biological Process: vulval development [IMPLink to PubMed article]
    positive regulation of meiosis [IGILink to PubMed article][IMPLink to PubMed article]
    feminization of hermaphroditic germ-line [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    spermatogenesis [IMPLink to PubMed article]
    regulation of meiosis [IMPLink to PubMed articleLink to PubMed article]
    germ-line stem cell division [IMPLink to PubMed article]
    cytokinesis [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed articleLink to PubMed article]
    masculinization of hermaphroditic germ-line [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    negative regulation of binding [IDALink to PubMed article]
    nuclear division [IMPLink to PubMed article]
    germ-line sex determination [IMPLink to PubMed article]
    Molecular Function: protein domain specific binding [IPILink to PubMed article]
    protein binding [IPILink to PubMed article]
    RNA binding [IEALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEQSHEKDH DEAHSYNPFV RSAVEYDADT RLQMAENAAS ARKLFVSSAL KDIIVNPENF  60
   61 YHDFQQSAQM AEDANQRRQV SYNTKREAHI HQLKAQGLPL PSNIPMIEIN PTRVTLNMEF 120
  121 ESQYYSLMTS DNGDHENVAS IMAETNTLIQ LPDRSVGGTT PDPFAQQVTI TGYFGDVDRA 180
  181 RMLMRRNCHF TVFMALSKMK MPLHELQAHV RQNPIQNVEM SFVDAPEKNG IVTTYLRITA 240
  241 REKNQHELIE AAKRLNEILF RESPAPENNF TLHFTLSTYY VDQVLGSSST AQLMPVIERE 300
  301 TTTIISYPCY NNRNETRGNI YEIKVVGNID NVLKARRYIM DLLPISMCFN IKNTDMAEPS 360
  361 RVSDRNIHMI IDESGIILKM TPSVYEPADL LSGEVPLNCA SLRSKEFNIK KLYTAYQKVL 420
  421 SKKFDFIAPQ PNDYDNSIWH HSLPANFLKN FNMPCRGELS DGSNGRRHRS SSIASSRSKH 480
  481 SYMSKGKQFS ESSGGPSRSH TRVSSFSENS STVPIMQFPT PHFAPPMLTP HHHMLKYVYL 540
  541 QQHQQAQTFL KGAAGLHPGT HIMFPPPIIV DGSFGARYSS NIYPFSYIVP QNFNFLNGNF 600
  601 GHL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] PSI-BLAST 9.0 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
    2 View Details [206..261] deduced N/A No confident structure predictions are available.
    3 View Details [262..420] PSI-BLAST 22.0 No description for 2annA was found.
    4 View Details [421..603] MSA 2.172995 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle