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Protein Overview: egl-13

General Information:
Name(s) found: egl-13 / CE28487 [WormBase]
Description(s) found:
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  • WBGene00001182 locus:egl-13 status:Confirmed UniProt:Q23045 protein_id:CCD74407.1 [WormBase]
  • gi|71996900|ref|NP_001024918.1| EGg Laying defective family member (egl-13) [Caenorhabditis elegans] [NCBI NR]
  • gi|4218968|gb|AAD12252.1| Sox domain protein COG-2 [Caenorhabditis elegans] [NCBI NR]
  • ref|NP_508955.1| EGg Laying defective EGL-13, Connection Of Gonad defective COG-2, Sox domain protein (52.3 kD) (egl-13) [Caenorhabditis elegans] [NCBI NR]
  • gi|14916358|gb|AAB04597.2| Egg laying defective protein 13, isoform a [Caenorhabditis elegans] [NCBI NR]
  • pir||T43675 cog-2 protein - Caenorhabditis elegans [NCBI NR]
  • Transcription factor egl-13 OS=Caenorhabditis elegans GN=egl-13 PE=1 SV=2 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE28487 WBGene00001182 locus:egl-13 status:Confirmed TR:Q23045 protein_id:AAB04597.2 [wormpep150.fasta]
  • 28487 WBGene00001182 locus:egl-13 status:Confirmed TR:Q23045 protein_id:AAB04597.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • EGg Laying defective EGL-13, Connection Of Gonad defective COG-2, Sox domain protein (52.3 kD) (egl-13) [Caenorhabditis elegans]gi|14916358|gb|AAB04597.2| Egg laying defective protein 13, isoform a [Caenorhabditis elegans]gi|4218968|gb|AAD12252.1| Sox d [nrdb_11152004_Chlamydomonas]
  • locus:egl-13 status:Confirmed TR:Q23045 protein_id:AAB04597.2 [wormpep115.fasta.reversed]
  • CE28487 locus:egl-13 status:Confirmed [wormpep80.hongbin]
  • CE28487 WBGene00001182 locus:egl-13 status:Confirmed UniProt:Q23045_CAEEL protein_id:AAB04597.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE28487 WBGene00001182 locus:egl-13 status:Confirmed UniProt:Q23045_CAEEL protein_id:AAB04597.2| [wormORF-contam.fasta]
  • EGg Laying defective family member (egl-13) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Sox domain protein COG-2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Egg laying defective protein 13, isoform a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE28487 WBGene00001182 locus:egl-13 status:Confirmed UniProt:Q23045 protein_id:AAB04597.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE28487 WBGene00001182 locus:egl-13 status:Confirmed UniProt:Q23045 protein_id:CCD74407.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • CE28487 WBGene00001182 locus:egl-13 status:Confirmed UniProt:Q23045 protein_id:CCD74407.1 Transcription factor egl-13 [c_elegans-PRJNA13758-WS250-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 470 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: vulval development [IMPLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    oviposition [IMPLink to PubMed article]
    anatomical structure morphogenesis [IMPLink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    plasma membrane fusion [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    transcription factor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRRKANPT KLSENAKKLA KEVENSQEEN DCDMLAKPQT PTIIIPGHMD DTPNPAGSPH  60
   61 DASIKSSSST ISDHTSTSAT TGISDFPDIL AQTEHGCSVL IDGNHLREII NSVDTQDGKQ 120
  121 DLLSDVIRQL TSIKERLTND ESPVKDDLKE DPDDMSPMLH AGNFDSEMLL RQHELMQHQQ 180
  181 QQMIIANMLK ATQSLPLLFN GGLNYEAILN NPVLNATIAG HLPNPLASNI SLLQKSISAK 240
  241 LAAAGNMQTV EKVETPLNLS KDTPSPTAIP QSPLSGFRLP YSLGTNYGSD GQLFNNCSPN 300
  301 SSGKSTPGNT SVTSEVATPR PQAKSPNHIK RPMNAFMVWA RDERRKILKA YPDMHNSNIS 360
  361 KILGSRWKGM SNSEKQPYYE EQSRLSKLHM EQHPDYRYRP RPKRTCVIDG KKVRVNEYKT 420
  421 IMKTKKDLMW GDEPGFSQPS DLQMDLASHV NLLNDLTQHH HQSHLLQTAE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] deduced N/A No confident structure predictions are available.
    2 View Details [85..141] MSA 1.067993 View MSA. No confident structure predictions are available.
    3 View Details [142..326] MSA 11.283997 View MSA. No confident structure predictions are available.
    4 View Details [327..470] PSI-BLAST 35.30103 No description for 2gzkA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  2.13364477654991 bayes_pls_golite062009
  • DNA binding
    		•  1.53868224871484 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.08780465158402 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.818311652354687 bayes_pls_golite062009
  • transcription factor activity
    		•  0.53515597626729 bayes_pls_golite062009
  • protein binding
    		•  0.436111251185035 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.42024807191387 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle