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Protein Overview: egl-18

General Information:
Name(s) found: egl-18 / CE28339 [WormBase]
Description(s) found:
Found 20 descriptions.
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  • WBGene00001186 locus:egl-18 status:Confirmed UniProt:G5EGF4 protein_id:CCD71858.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 376 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article][IEALink to PubMed article]
    Biological Process: negative regulation of multicellular organism growth [IMPLink to PubMed article]
    cellular membrane fusion [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    cell fate specification [IMPLink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article][ISSLink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSISIMTETR PESAEQQHHE VLQRPSDEPC SGCKQLQKDV AKTISMVMER MDKLQYRLDE  60
   61 LLKENNELKS SSVSSGKASP SPAESRSSPK LVETVVAPVS GARKRKPKER SPPAAASPLP 120
  121 DFSNLMNGFM FDPLNMSNPN GMMQLLSMVQ QQQQQQQHHQ HIENQQSVSP PQSKSVKIED 180
  181 PMDQDVKQEE SERSDIPTAT EAQNLLDALT AQFSSNGQAT STTSPPSSSS QVQAVIEAVA 240
  241 TPSSQSQDSS MFEKTETSGD PNAARCSNCR TDKTTAWRRD AEGKLVCNPC GLYYRLHKVR 300
  301 RPIEMRKNHI QQRYRRKNKE KESSAATQIF NQLLTQMPTM ATGGVSTDGA INTFNLLEQI 360
  361 SQFTQAQELM NSSATF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..170] MSA 6.196995 View MSA. No confident structure predictions are available.
    2 View Details [171..261] deduced N/A No confident structure predictions are available.
    3 View Details [262..376] PSI-BLAST 15.154902 Erythroid transcription factor GATA-1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  1.42599378647208 bayes_pls_golite062009
  • protein binding
    		•  0.576254539963841 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.50063581643098 bayes_pls_golite062009
  • DNA binding
    		•  0.15755076348446 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle