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Protein Overview: CE27459

General Information:
Name(s) found: CE27459 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00022491 status:Partially_confirmed UniProt:Q95Y73 protein_id:AAK29716.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 689 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    intracellular [IEALink to PubMed article]
    Biological Process: translational termination [IEALink to PubMed article]
    translational elongation [IEALink to PubMed article]
    Molecular Function: GTP binding [IEALink to PubMed article]
    translation elongation factor activity [IEALink to PubMed article]
    GTPase activity [IEALink to PubMed article]
    translation release factor activity, codon specific [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLLLLLSR RCYSTPPPPP APSKLRNIGV IAHVDAGKTT VTERLLYLAG AIHVAGHVDK  60
   61 GNTVTDFLDI ERERGITVQS AAVNLDWKGH RINLIDTPGH VDFRVEVERC VRVLDGIVVV 120
  121 IDGSAGVQPQ TLTVWRQSSK FKLPAHFFIN KMDKLAANFE NSVDSVEQKL GVRAVKLVVP 180
  181 LPENRGFNRG FLDILHSKML PGNSKNWQNP PKNSPEAELL AEHKSELCFT LADSHADFQS 240
  241 KFLDEFDGNS EKIDVIEMKS VLRELTCASK IATISCGSAI THDKRRGQLS YMRIYTGSLH 300
  301 NNSTIFNTSQ MTSEGPLKLF TPYADELRLV EQVSAGNITV VAGLQTTVTG DTVVASSASA 360
  361 EKACQKLAGS ESSLLSPKDG NSVVFSGIES PDAVFFCCIE PPSNRQLNQF NKALEELTRE 420
  421 DPSMKIRFDR DTGQTIVETQ GELHLEAIKD RLKRNYKLDV FIGKLQVAYR EMLTEELSYT 480
  481 AKVEDGLSEK KRPEFVQLTM RLEPTQAHIP FKKIELELPQ TARPVRLDWQ KAVNEGCSNA 540
  541 LQNGPLASYP VHAVRVVLTE CIVSGGKINP ALLSACAQKC VSEALSSGEM VLTEPVMEVQ 600
  601 IEIRNDDPTQ PILNELLRRR AHFEHSDATE STEIRRICAI LPLSETENLS KTVRTLTSGF 660
  661 GDISVQFRGY QQVTEHEKME ILKKRATGY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..689] PSI-BLAST 175.0 Elongation factor G (EF-G), domain II; Elongation factor G (EF-G), N-terminal (G) domain; Elongation factor G (EF-G), domain IV; Elongation factor G (EF-G)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of ribosome
    		•  4.9869754621766 bayes_pls_golite062009
  • structural molecule activity
    		•  4.395910578613 bayes_pls_golite062009
  • translation release factor activity
    		•  2.49148102494524 bayes_pls_golite062009
  • translation termination factor activity
    		•  2.46464632547226 bayes_pls_golite062009
  • motor activity
    		•  2.12049963052212 bayes_pls_golite062009
  • microtubule motor activity
    		•  2.06077854565894 bayes_pls_golite062009
  • translation elongation factor activity
    		•  1.78840251801545 bayes_pls_golite062009
  • RNA binding
    		•  1.40868766468494 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • binding
    		•  0.872512498570204 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.555181608481691 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.499351238958464 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.368412900600617 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.337324481645901 bayes_pls_golite062009
  • kinase activity
    		•  0.237670019875888 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.2302541318658 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.205488803771958 bayes_pls_golite062009
  • protein binding
    		•  0.0913090112555771 bayes_pls_golite062009
  • DNA binding
    		•  0.0880977286684361 bayes_pls_golite062009
  • mRNA binding
    		•  0.0491645692672305 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.0067235917574795 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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