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Protein Overview: ddr-1

General Information:
Name(s) found: ddr-1 / CE27088 [WormBase]
Description(s) found:
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  • WBGene00016104 locus:ddr-1 Protein tyrosine kinase status:Partially_confirmed UniProt:Q18163 protein_id:AAK39199.1 [WormBase]
  • gi|17550630|ref|NP_508926.1| Discoidin Domain Receptor family member (ddr-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|13775382|gb|AAK39199.1| Hypothetical protein C25F6.4 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE27088 WBGene00016104 Protein tyrosine kinase status:Partially_confirmed TR:Q18163 protein_id:AAK39199.1 [wormpep150.fasta]
  • 27088 WBGene00016104 Protein tyrosine kinase status:Partially_confirmed TR:Q18163 protein_id:AAK39199.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • receptor tyrosine kinase. family member (86.5 kD) (XG83) [Caenorhabditis elegans]gi|13775382|gb|AAK39199.1| Hypothetical protein C25F6.4 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • Protein tyrosine kinase status:Partially_confirmed TR:Q18163 protein_id:AAK39199.1 [wormpep115.fasta.reversed]
  • CE27088 Protein tyrosine kinase status:Partially_confirmed TR:Q18163 protein_id:AAK39199.1 [wormpep80.hongbin]
  • CE27088 WBGene00016104 locus:ddr-1 Protein tyrosine kinase status:Partially_confirmed UniProt:Q18163_CAEEL protein_id:AAK39199.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE27088 WBGene00016104 locus:ddr-1 Protein tyrosine kinase status:Partially_confirmed UniProt:Q18163_CAEEL protein_id:AAK39199.1| [wormORF-contam.fasta]
  • C25F6.4 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein C25F6.4 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE27088 WBGene00016104 locus:ddr-1 Protein tyrosine kinase status:Partially_confirmed TR:Q18163 protein_id:AAK39199.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta]
  • CE27088 WBGene00016104 locus:ddr-1 Protein tyrosine kinase status:Partially_confirmed UniProt:Q18163 protein_id:AAK39199.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
    • Organism: Caenorhabditis elegans
    Length: 767 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: signal transduction [IEALink to PubMed article]
    cell adhesion [IEALink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    non-membrane spanning protein tyrosine kinase activity [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIALVLLAI YGTTTTNTLR IDQCGENALG MQNGDIADSQ ITASSSFDKQ SVGPQNARLH  60
   61 SELASGAWCP KPQINSKSYE FLQVTLNDTF LITSVETQGR YGNGTGREFA SHYMIDYLRP 120
  121 GSQWIRYKNR TGHVYMDGNF DTTTPVIRVL DPPIVASRIR FVPSSKNTRT VCMRAEIHGC 180
  181 KHEGVTYYST VPDGSRLDTL DFKDSMFEDS QIYTESGIKR YGSWPANRRF RSAASPFEKN 240
  241 QMNNSWIGWN RDTTDGRITI LFEFEEVHNF TDVVLATFGN RIDGIDVIFS QDGKTFPLFS 300
  301 QISSSERQSL NNTSRRYDFR VPLHNRAGRK VRISIKFSSD WMFLTEVHFT SAANLTLLSE 360
  361 KIPPPSSAAT QQLLVVCGII FLTIFACVAY CVSVCLKRRQ KNKSVDSNVK KDLIITHMGN 420
  421 KPTCHVFPSN GKLSNGHYEV ANDILYARSQ KSTLLSVSSK STFSCRAIPP TWTDFNFPPP 480
  481 PEGREEHTYS QPVSPENSSN GSYKSVRKIQ ALKKYPSSAL LIGKAIGEGK FTMIKECIIF 540
  541 GGLKCAHKST KEEDCVHGTR ALGDEIACLL QCGRHPRIVE LFGVDESYNL LLEHVEYGCI 600
  601 RNFWMASEAP LDTEFLVRIC KDIYSAMAYL ESIRIVHGHF TPNNILMDGE FHAKVCSPRG 660
  661 PSHHAQLRYS APESIVNNEF THKSDAWAVA TTVYEMAYQC RQRPYEELTN EQIVDNACAL 720
  721 LDHQPNAVVP LMPTVFNYEI LQLLTRCFRV DQLERPTFER LVKPFQD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..309] PSI-BLAST 84.0 No description for 2orxA was found.
    2 View Details [310..767] PSI-BLAST 62.69897 Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • protein kinase activity
    		•  1.78639464829681 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.68813706140222 bayes_pls_golite062009
  • kinase activity
    		•  1.50836670989773 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.31704288481409 bayes_pls_golite062009
  • binding
    		•  1.2105299206356 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.88511260350082 bayes_pls_golite062009
  • transferase activity
    		•  0.793030362112723 bayes_pls_golite062009
  • protein binding
    		•  0.407352883221124 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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