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View Structure Prediction Details

Protein: ddr-1
Organism: Caenorhabditis elegans
Length: 767 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ddr-1.

Description E-value Query
Range
Subject
Range
gi|109499000, gi... - gi|109499000|ref|XP_001076634.1| PREDICTED: similar to Discoidin domain-containing receptor 2 precur...
550.0 [0..20] [765..19]

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Predicted Domain #1
Region A:
Residues: [1-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIALVLLAI YGTTTTNTLR IDQCGENALG MQNGDIADSQ ITASSSFDKQ SVGPQNARLH  60
   61 SELASGAWCP KPQINSKSYE FLQVTLNDTF LITSVETQGR YGNGTGREFA SHYMIDYLRP 120
  121 GSQWIRYKNR TGHVYMDGNF DTTTPVIRVL DPPIVASRIR FVPSSKNTRT VCMRAEIHGC 180
  181 KHEGVTYYST VPDGSRLDTL DFKDSMFEDS QIYTESGIKR YGSWPANRRF RSAASPFEKN 240
  241 QMNNSWIGWN RDTTDGRITI LFEFEEVHNF TDVVLATFGN RIDGIDVIFS QDGKTFPLFS 300
  301 QISSSERQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.0
Match: 2orxA
Description: No description for 2orxA was found.

Predicted Domain #2
Region A:
Residues: [310-767]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNNTSRRYDF RVPLHNRAGR KVRISIKFSS DWMFLTEVHF TSAANLTLLS EKIPPPSSAA  60
   61 TQQLLVVCGI IFLTIFACVA YCVSVCLKRR QKNKSVDSNV KKDLIITHMG NKPTCHVFPS 120
  121 NGKLSNGHYE VANDILYARS QKSTLLSVSS KSTFSCRAIP PTWTDFNFPP PPEGREEHTY 180
  181 SQPVSPENSS NGSYKSVRKI QALKKYPSSA LLIGKAIGEG KFTMIKECII FGGLKCAHKS 240
  241 TKEEDCVHGT RALGDEIACL LQCGRHPRIV ELFGVDESYN LLLEHVEYGC IRNFWMASEA 300
  301 PLDTEFLVRI CKDIYSAMAY LESIRIVHGH FTPNNILMDG EFHAKVCSPR GPSHHAQLRY 360
  361 SAPESIVNNE FTHKSDAWAV ATTVYEMAYQ CRQRPYEELT NEQIVDNACA LLDHQPNAVV 420
  421 PLMPTVFNYE ILQLLTRCFR VDQLERPTFE RLVKPFQD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 62.69897
Match: 1opkA
Description: Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein kinase activity 1.78639464829681 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.68813706140222 bayes_pls_golite062009
kinase activity 1.50836670989773 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.31704288481409 bayes_pls_golite062009
binding 1.2105299206356 bayes_pls_golite062009
protein serine/threonine kinase activity 0.88511260350082 bayes_pls_golite062009
transferase activity 0.793030362112723 bayes_pls_golite062009
protein binding 0.407352883221124 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle