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Protein Overview: smg-4

General Information:
Name(s) found: smg-4 / CE26973 [WormBase]
Description(s) found:
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  • WBGene00004882 locus:smg-4 status:Confirmed UniProt:Q20445 protein_id:CAA94820.2 [WormBase]
  • gi|25148414|ref|NP_741601.1| Suppressor with Morphological effect on Genitalia family member (smg-4) [Caenorhabditis elegans] [NCBI NR]
  • gi|13548374|emb|CAA94820.2| C. elegans protein F46B6.3a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE26973 WBGene00004882 locus:smg-4 status:Confirmed TR:Q20445 protein_id:CAA94820.2 [wormpep150.fasta]
  • 26973 WBGene00004882 locus:smg-4 status:Partially_confirmed TR:Q20445 protein_id:CAA94820.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • suppressor with Morphological effect on Genitalia SMG-4, Male ABnormal MAB-14, UPF3 (38.9 kD) (smg-4) [Caenorhabditis elegans]gi|13548374|emb|CAA94820.2| Hypothetical protein F46B6.3a [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • 26973 WBGene00004882 locus:smg-4 status:Confirmed TR:Q20445 protein_id:CAA94820.2 [wormpep150-phg-orf-ecoli-rand.fasta]
  • locus:smg-4 status:Partially_confirmed TR:Q20445 protein_id:CAA94820.2 [wormpep115.fasta.reversed]
  • CE26973 locus:smg-4 status:Partially_confirmed TR:Q20445 protein_id:CAA94820.2 [wormpep80.hongbin]
  • CE26973 WBGene00004882 locus:smg-4 status:Confirmed UniProt:Q20445_CAEEL protein_id:CAA94820.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE26973 WBGene00004882 locus:smg-4 status:Confirmed UniProt:Q20445_CAEEL protein_id:CAA94820.2| [wormORF-contam.fasta]
  • Suppressor with Morphological effect on Genitalia family member (smg-4) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein F46B6.3a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE26973 WBGene00004882 locus:smg-4 status:Confirmed UniProt:Q20445 protein_id:CAA94820.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • Isoform of Q8WQF3, Suppressor with Morphological effect on Genitalia OS=Caenorhabditis elegans GN=smg-4 PE=1 SV=2 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 329 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    perinuclear region of cytoplasm [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: hermaphrodite genitalia development [IMPLink to PubMed article]
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [IGILink to PubMed article]
    male genitalia development [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDSKDGHVK VVLRRLPKYM TEHEVLEQIS PLPEEVIGTY FHPANFSFDR CAYATLTVNF  60
   61 SEYCDSMMEF ERRFDGYIFV DSRGNDSAAV VEAASNQNFA KCDRNRMKED TRVGAILTDK 120
  121 YYLDFCKKLE EERAIPILTL EQQIRKLNQP DDARTQIDKM ETPLVKYFFE KETGKRRDYD 180
  181 ARRQRRDEKR AEKRDKVDKF EKHKNVLDIL MKPSVPMAST SATTSKKDLK KEKPMTEKEK 240
  241 ERWEKQDAKR KERNMIRKQK FLDEKKKKHE EREQDGPRVP RDKKKERLAK PPRPSPAKTV 300
  301 GEQQGEDWIK KLTDPKSAPM KKKHDSPPN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..101] PSI-BLAST 30.0 The structural basis of the interaction between nonsense mediated decay factors UPF2 and UPF3
    2 View Details [102..329] MSA 5.123993 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  3.75748736237159 bayes_pls_golite062009
  • mRNA binding
    		•  2.67679675039933 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.39584426231036 bayes_pls_golite062009
  • binding
    		•  1.71154446874967 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.61170301639809 bayes_pls_golite062009
  • protein binding
    		•  0.426607329742248 bayes_pls_golite062009
    		• 0.24850555804347 bayes_pls_golite062009
  • hydrolase activity
    		•  0.0430264134452161 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle