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Protein Overview: nhr-11

General Information:
Name(s) found: nhr-11 / CE26841 [WormBase]
Description(s) found:
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  • WBGene00003610 locus:nhr-11 Nuclear hormone receptor family member nhr-11 status:Confirmed UniProt:Q23294 protein_id:CAA92572.2 [WormBase]
  • gi|71999681|ref|NP_501575.3| Nuclear Hormone Receptor family member (nhr-11) [Caenorhabditis elegans] [NCBI NR]
  • gi|38147780|gb|AAR11983.1| nuclear receptor NHR-11 [Caenorhabditis elegans] [NCBI NR]
  • gi|30315990|sp|Q23294.3|NHR11_CAEEL RecName: Full=Nuclear hormone receptor family member nhr-11 [NCBI NR]
  • gi|13548494|emb|CAA92572.2| C. elegans protein ZC410.1a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|115533086|ref|NP_001041063.1| Nuclear Hormone Receptor family member (nhr-11) [Caenorhabditis elegans] [NCBI NR]
  • Nuclear hormone receptor family member nhr-11 OS=Caenorhabditis elegans GN=nhr-11 PE=3 SV=3 [Swiss-Prot]
  • (Q23294) Nuclear hormone receptor family member nhr-11 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE26841 WBGene00003610 locus:nhr-11 nuclear hormone receptor status:Confirmed SW:Q23294 protein_id:CAA92572.2 [wormpep150.fasta]
  • nuclear receptor NHR-11 [Caenorhabditis elegans]gi|13548494|emb|CAA92572.2| Hypothetical protein ZC410.1 [Caenorhabditis elegans]gi|30315990|sp|Q23294|NH11_CAEEL Nuclear hormone receptor family member nhr-11 [nrdb_11152004_Chlamydomonas]
  • 26841 WBGene00003610 locus:nhr-11 nuclear hormone receptor status:Confirmed SW:Q23294 protein_id:CAA92572.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • locus:nhr-11 nuclear hormone receptor status:Confirmed SW:Q23294 protein_id:CAA92572.2 [wormpep115.fasta.reversed]
  • CE26841 locus:nhr-11 nuclear hormone receptor status:Partially_confirmed TR:Q23294 protein_id:CAA92572.2 [wormpep80.hongbin]
  • CE26841 WBGene00003610 locus:nhr-11 nuclear hormone receptor status:Confirmed UniProt:Q23294 protein_id:CAA92572.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE26841 WBGene00003610 locus:nhr-11 nuclear hormone receptor status:Confirmed UniProt:Q23294 protein_id:CAA92572.2| [wormORF-contam.fasta]
  • Hypothetical protein ZC410.1a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • nuclear receptor NHR-11 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Nuclear Hormone Receptor family member (nhr-11) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Nuclear hormone receptor family member nhr-11 [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE26841 WBGene00003610 locus:nhr-11 status:Confirmed UniProt:Q23294 protein_id:CAA92572.2 Nuclear hormone receptor family member nhr-11 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 459 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    steroid hormone receptor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPLCAVCES PTAFTLHFGG RCCKACAAFF RRTIALDLKY ECAADDPCEI HFKFPGMRLV  60
   61 CRECRLRKCY SAGMRSELVR SKRENFACTR RKDSRNNSDA APNSNSPSTR QSSSPEEMDD 120
  121 WSFQMFEEKP KIEDLPLTPS ISHPPLPTQL MPEESSRTSS FDGGYCSSYP SSSAATHPSP 180
  181 PGMLYSIENN SILQYYHSME TGLCSKRRIM YTNTGMDFIL DTHANLQCPF TVNDLRPHDY 240
  241 RNFRGMLRHD FVMLFDYATR FPEFNSFTSH EKNMFYRQIV AVDFILSSAY YTAKLGQAHR 300
  301 QMVLTNGEYL NMDPLPMSGN EIDARRYFDC DEDFSKYRAL MPMHIAIWEE SIVPFSKLNV 360
  361 TFEEFCLLKA LTVWQATYFK LTENGREKCR RQRNIIIGFL SKMCHSPGGG GEHRVGELLM 420
  421 SMNYLRESAQ KLTTSYVMLT VFNVLNCDSM LHEMLNFQY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..155] PSI-BLAST 16.30103 No description for 2hanB was found.
    2 View Details [156..459] PSI-BLAST 55.69897 LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.270879137859077 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  1.15996699473685 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.46162010671465 bayes_pls_golite062009
  • protein binding
    		•  0.33427459029264 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.15459949087509 bayes_pls_golite062009
  • DNA binding
    		•  0.14395376162921 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle