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View Structure Prediction Details

Protein: nhr-11
Organism: Caenorhabditis elegans
Length: 459 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhr-11.

Description E-value Query
Range
Subject
Range
gi|73984965 - gi|73984965|ref|XP_541755.2| PREDICTED: similar to nuclear receptor subfamily 2, group C, member 2 [...
276.0 [0..3] [458..152]

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Predicted Domain #1
Region A:
Residues: [1-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPLCAVCES PTAFTLHFGG RCCKACAAFF RRTIALDLKY ECAADDPCEI HFKFPGMRLV  60
   61 CRECRLRKCY SAGMRSELVR SKRENFACTR RKDSRNNSDA APNSNSPSTR QSSSPEEMDD 120
  121 WSFQMFEEKP KIEDLPLTPS ISHPPLPTQL MPEES

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.30103
Match: 2hanB
Description: No description for 2hanB was found.

Predicted functions:

Term Confidence Notes
binding 0.270879137859077 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [156-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRTSSFDGGY CSSYPSSSAA THPSPPGMLY SIENNSILQY YHSMETGLCS KRRIMYTNTG  60
   61 MDFILDTHAN LQCPFTVNDL RPHDYRNFRG MLRHDFVMLF DYATRFPEFN SFTSHEKNMF 120
  121 YRQIVAVDFI LSSAYYTAKL GQAHRQMVLT NGEYLNMDPL PMSGNEIDAR RYFDCDEDFS 180
  181 KYRALMPMHI AIWEESIVPF SKLNVTFEEF CLLKALTVWQ ATYFKLTENG REKCRRQRNI 240
  241 IIGFLSKMCH SPGGGGEHRV GELLMSMNYL RESAQKLTTS YVMLTVFNVL NCDSMLHEML 300
  301 NFQY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.69897
Match: 1lbdA
Description: LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.15996699473685 bayes_pls_golite062009
transcription regulator activity 0.46162010671465 bayes_pls_golite062009
protein binding 0.33427459029264 bayes_pls_golite062009
nucleic acid binding 0.15459949087509 bayes_pls_golite062009
DNA binding 0.14395376162921 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle