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Protein Overview: avr-14

General Information:
Name(s) found: avr-14 / CE26421 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00000232 locus:avr-14 status:Confirmed UniProt:Q95Q97 protein_id:CCD61324.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 430 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic membrane [IEALink to PubMed article]
    membrane [IDALink to PubMed article][IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: ion transport [IDALink to PubMed article][IEALink to PubMed article]
    locomotion involved in locomotory behavior [IGILink to PubMed article][IMPLink to PubMed article]
    regulation of pharyngeal pumping [IGILink to PubMed article][IMPLink to PubMed article]
    response to drug [IGILink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: drug binding [IGILink to PubMed article]
    neurotransmitter receptor activity [IEALink to PubMed article]
    extracellular ligand-gated ion channel activity [IEALink to PubMed article]
    extracellular-glutamate-gated chloride channel activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWHYRLTTIL LIISIIHSIR AKRKLKEQEI IQRILKDYDW RVRPRGMNAT WPDTGGPVLV  60
   61 TVNIYLRSIS KIDDVNMEYS AQFTFREEWT DQRLAYERYE ESGDTEVPPF VVLATSENAD 120
  121 QSQQIWMPDT FFQNEKEARR HLIDKPNVLI RIHKNGQILY SVRLSLVLSC PMSLEFYPLD 180
  181 RQNCLIDLAS YAYTTQDIKY EWKEKKPIQQ KDGLRQSLPS FELQDVVTDY CTSLTNTGEY 240
  241 SCARVVLRLR REYSYYLIQL YIPCIMLVVV SWVSFWLDKD AVPARVSLGV TTLLTMTTQA 300
  301 SGINSKLPPV SYIKAVDVWI GVCLAFIFGA LLEYAVVNYY GRKEFLRKEK KKKTRIDDCV 360
  361 CPSDRPPLRL DLSAYRSVKR LPIIKRISEI LSTNIDISRR VDLMSRLTFP LTFFSFLIFY 420
  421 YVAYVKQSRD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..430] PSI-BLAST 63.69897 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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