Protein Overview: cua-1

General Information:
Name(s) found:	cua-1 / CE26305 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00000834 locus:cua-1 status:Confirmed UniProt:G5EE14 protein_id:CAA21773.2 [WormBase] gi\|9367167\|emb\|CAA21773.2\| C. elegans protein Y76A2A.2a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|9367132\|emb\|CAB07620.2\| C. elegans protein Y76A2A.2a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] pir\|\|JC5573 copper-transporting ATPase (EC 3.6.1.-) P-type - Caenorhabditis elegans [NCBI NR] gi\|2217940\|dbj\|BAA20550.1\| copper transporting ATPase [Caenorhabditis elegans] [NCBI NR] gi\|17556548\|ref\|NP_499778.1\| CU (copper) ATPase family member (cua-1) [Caenorhabditis elegans] [NCBI NR] [wormpep67.fasta] CE26305 WBGene00000834 locus:cua-1 Heavy-metal-associated domain containing proteins (2 domains), E1-E2 ATPases (2 domains) status:Confirmed TR:O17737 protein_id:CAA21773.2 [wormpep150.fasta] 26305 WBGene00000834 locus:cua-1 Heavy-metal-associated domain containing proteins (2 domains), E1-E2 ATPases (2 domains) status:Confirmed TR:O17737 protein_id:CAA21773.2 [wormpep130-phg-ecoli-orf-rand.fasta] Cu++-ATpase, copper transporter, P-type ATPase, putative heavy metal ion transporter similar to human Menkes disease-associated protein (133.5 kD) (cua-1) [Caenorhabditis elegans]gi\|9367132\|emb\|CAB07620.2\| Hypothetical protein Y76A2A.2 [Caenorhabditis el [nrdb_11152004_Chlamydomonas] locus:cua-1 Heavy-metal-associated domain containing proteins (2 domains), E1-E2 ATPases (2 domains) status:Confirmed TR:O17737 protein_id:CAA21773.2 [wormpep115.fasta.reversed] CE26305 Heavy-metal-associated domain containing proteins (2 domains), E1-E2 ATPases (2 domains) status:Partially_confirmed TR:O17737 protein_id:CAA21773.2 [wormpep80.hongbin] CE26305 WBGene00000834 locus:cua-1 Heavy-metal-associated domain containing proteins (2 domains), E1-E2 ATPases (2 domains) status:Confirmed UniProt:O17737_CAEEL protein_id:CAB07620.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE26305 WBGene00000834 locus:cua-1 Heavy-metal-associated domain containing proteins (2 domains), E1-E2 ATPases (2 domains) status:Confirmed UniProt:O17737_CAEEL protein_id:CAB07620.2\| [wormORF-contam.fasta] Hypothetical protein Y76A2A.2 [Caenorhabditis elegans] [nr-271106-contam.fasta] CU (copper) ATPase family member (cua-1) [Caenorhabditis elegans] [nr-271106-contam.fasta] copper transporting ATPase [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE26305 WBGene00000834 locus:cua-1 Heavy-metal-associated domain containing proteins (2 domains), E1-E2 ATPases (2 domains) status:Confirmed UniProt:O17737 protein_id:CAB07620.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] CE26305 WBGene00000834 locus:cua-1 Heavy-metal-associated domain containing proteins (2 domains), E1-E2 ATPases (2 domains) status:Confirmed UniProt:G5EE14 protein_id:CAA21773.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] CE26305 WBGene00000834 locus:cua-1 status:Confirmed UniProt:G5EE14 protein_id:CAA21773.2 [wormpep246-ecoli-contam.fasta] CU (Copper) ATPase OS=Caenorhabditis elegans GN=cua-1 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	1238 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA] vacuolar membrane [IDA]
Biological Process:	proton transport [IEA] magnesium ion transport [IEA] locomotion [IMP ] determination of adult lifespan [IMP] positive regulation of growth rate [IMP] metabolic process [IEA] L-serine biosynthetic process [IEA] lipopolysaccharide biosynthetic process [IEA] transport [IEA] potassium ion transport [IEA] copper ion transport [IDA][IEA] locomotory behavior [IMP ] nematode larval development [IMP] calcium ion transport [IEA] metal ion transport [IEA]
Molecular Function:	ATPase activity [IEA] magnesium-importing ATPase activity [IEA] ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [IEA] hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [IEA] calcium ion transmembrane transporter activity [IEA] metal ion transmembrane transporter activity [IEA] copper ion transmembrane transporter activity [IDA] calcium-transporting ATPase activity [IEA] potassium-transporting ATPase activity [IEA] magnesium ion binding [IEA] ATP binding [IEA] phosphoserine phosphatase activity [IEA] copper-exporting ATPase activity [IEA] copper ion binding [IEA] catalytic activity [IEA] metal ion binding [IEA] calcium ion binding [IEA] 3-deoxy-manno-octulosonate-8-phosphatase activity [IEA] hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSENVSLLDG SPLPSRPSTS SIPRPSPSKN IQLLVDFGAP KTDGNVQETM LEIKGMTCNS  60
   61 CVKNIQDVIG AKPGIHSIQV NLKEENAKCS FDTTKWTAEK VAEAVDDMGF DCKVLKKEPP 120
  121 TQMAEKPKIR RAIVSIEGMT CHACVNNIQD TVGSKDGIVK IVVSLEQKQG TVDYNSEKWN 180
  181 GESVAESIDD MGFDCKLITD QEIAAVEPQK ASTTKLSISP LKTVDLSDGK VELQLNGVKY 240
  241 SKEGSSDHLE KCTFAVEGMT CASCVQYIER NISKIEGVHS IVVALIAAKA EVIYDGRVTS 300
  301 SDAIREHMTG ELGYKATLLD SMGANPNYSK IRLIIGNLST ESDANRIESH VLSKSGIDSC 360
  361 NVSIATSMAL VEFSPQVIGP RDIINVVESL GFTADLATRD DQMKRLDHSD DVKKWRNTFF 420
  421 IALIFGVPVM IIMIIFHWIL RTPMHPDKQT PIFTPALSLD NFLLLCLCTP VQIFGGRYFY 480
  481 VASWKAIKHG NANMDVLIML STTIAYTYSI VVLLLAIIFK WPSSPMTFFD VPPMLIVFIA 540
  541 LGRMLEHKAK GKTSEALSKL MSLQAKEATL VTMDSEGRLT SEKGINIELV QRNDLIKVVP 600
  601 GAKVPVDGVV VDGKSSVDES FITGESMPVV KKPGSTVIGG SVNQKGVLIV KATHVGNDST 660
  661 LSQIVRLVEE AQTNRAPIQQ LADKIAGYFV PFVIVLSLFT LGVWIYIEYN SARNANLPPG 720
  721 LRFEEALKIA FEAAITVLAI ACPCSLGLAT PTAVMVGTGV GAANGILIKG GEPLESVHKV 780
  781 TTIVFDKTGT ITEGRPRVVQ IASFVNPSTM SLKLITFLSG ATEALSEHPI GNAVAAFAKQ 840
  841 LLNEPTWPNT SRFHVSAGHG VTCRIDSIRQ SFSSLALSGS TCEIPRLPDG QTITIPGTEV 900
  901 NLLQVSSKEV SQPNPDTANI VIGTERMMER HGIPVSEVVK MTLSEEQRKG HISVICAINA 960
  961 EVVAVISIAD QVKKEASLAI YTLREMGLRV VLLTGDNSKT AESTAKQVGI DEVFAEVLPN1020
 1021 QKQQKIKQLK GYKNKVAMVG DGVNDSPALA EANVGIAIAA GSDVAIESAG IVLVRNDLVD1080
 1081 VVGAIKLSKM TTRRIRLNFL FAIIYNAIGI PIAAGVFRPF GFMLQPWMAA AAMALSSVSV1140
 1141 VSSSLLLKNF RKPTIANLYT TSFKRHQKFL ESGSFQVQVH RGLDDSAVFR GAASSKLSIL1200
 1201 SSKVGSLLGS TTSIVSSGSS KKQRLLDNVG SDLEDLIV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: cua-1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: