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Protein Overview: pop-1

General Information:
Name(s) found: pop-1 / CE26031 [WormBase]
Description(s) found:
Found 14 descriptions.
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  • WBGene00004077 locus:pop-1 status:Confirmed UniProt:Q10666 protein_id:CCD73394.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 437 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    Biological Process: embryonic cleavage [IMPLink to PubMed article]
    polarity specification of proximal/distal axis [IGILink to PubMed articleLink to PubMed article]
    positive regulation of vulval development [IMPLink to PubMed article]
    spindle organization [IMPLink to PubMed article]
    regulation of cell fate specification [IGILink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    embryonic pattern specification [IGILink to PubMed article][IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    regulation of asymmetric cell division [IGILink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    positive regulation of transcription from RNA polymerase II promoter [IDALink to PubMed article]
    mesodermal cell fate determination [IGILink to PubMed article][IMPLink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [ISSLink to PubMed article]
    pharyngeal muscle development [IGILink to PubMed article][IMPLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    gastrulation with mouth forming first [IMPLink to PubMed article]
    Molecular Function: DNA binding [IEALink to PubMed article]
    RNA polymerase II transcription factor activity [IDALink to PubMed article][ISSLink to PubMed article]
    beta-catenin binding [IPILink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADEELGDEV KVFRRDEDAD DDPMISGETS EQQLADDKKE AVMEAELDGA GRNPSIDVLK  60
   61 SAFPKVEPMS PSFPGLMSHF SPGYSAAALP MFMPLFMNPY AAALRSPSLM FPMGAMSPTF 120
  121 PMFPPSPVYG AAIAAAAAKQ HFENMAPLNM RAGHPMNQMG MPPYMHPSSM APQNVDRRAQ 180
  181 GGGKAKKDDH VKKPLNAFMW FMKENRKALL EEIGNNEKQS AELNKELGKR WHDLSKEEQA 240
  241 KYFEMAKKDK ETHKERYPEW SARENYAVNK KKTKKRRDKS IPSENNDQKK CRARFGVNNT 300
  301 EMWCKFCKRK KKCEYATDRS GGSDITDSQD GRGTSGAYSS SSESPSPKAN AGIALTTQQQ 360
  361 QAAMMHTMLM QMRLGSTTGA STHVPSPLAS SSAGRSPLDA NASDSESDVE EEEDEQIDPT 420
  421 VMQQTHDMLM QESMCTI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..179] MSA 3.352994 View MSA. No confident structure predictions are available.
    2 View Details [180..279] PSI-BLAST 20.69897 No description for 2gzkA was found.
    3 View Details [280..437] FFAS03 1.11 Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.28152434895694 bayes_pls_golite062009
  • DNA binding
    		•  1.84781463420276 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.65696822227413 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.61604561096523 bayes_pls_golite062009
  • transcription factor activity
    		•  0.79924481726919 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.61748685686195 bayes_pls_golite062009
  • protein binding
    		•  0.413179898438205 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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