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Protein Overview: gcy-28

General Information:
Name(s) found: gcy-28 / CE25977 [WormBase]
Description(s) found:
Found 22 descriptions.
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  • WBGene00020131 locus:gcy-28 Guanylate cyclase status:Confirmed UniProt:Q965F7 protein_id:CCD73354.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 637 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: signal transduction [IEALink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    cyclic nucleotide biosynthetic process [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    non-membrane spanning protein tyrosine kinase activity [IEALink to PubMed article]
    phosphorus-oxygen lyase activity [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIDRKLSIFT RKKSTPPSES QKNGGLTPNS LQKAENGDCS PINEVQFRLP LNDRRVSSPS  60
   61 SEATRKKNSN EEDPENGAKK SLSLKNRKLS FGMVSFKSGS GGSVETIAQN NTQIYTKTAI 120
  121 FKGVVVAIKK LNIDPKKYPR LDLSRAQLME LKKMKDLQHD HITRFTGACI DFPHYCVVTE 180
  181 YCPKGSLEDI LENEKIELDK LMKYSLLHDL VKGLFFLHNS EIRSHGRLKS SNCVVDSRFV 240
  241 LKVTDFGLHR LHCLEEINLE EIGEHAYYKK MLWTAPELLR DSNAPPMGTQ KGDIYSFAII 300
  301 LHEMMFRKGV FALENEDLSP NEIVQRVRKP VSEDQEPLRP WVSETGEGEG DDALNDTLLS 360
  361 LMVACWSEDP HERPEVSSVR KAVRSLNRDN ETSNLVDNLL KRMEQYANNL EGLVEERTQE 420
  421 YLAEKKKVEE LLHQLLPPAI ADTLIAGRAV QAESYDCVTI YFSDIVGFTS LSSQSTPMQV 480
  481 VTLLNDLYLA FDGVVDNFKV YKVETIGDAY MVVSGLPERR DDHANQIAQM SLSLLHKVKN 540
  541 FVIRHRPHEQ LKLRIGMHSG SVVAGVVGSK MPRYCLFGDT VNTSSRMESN GLRMFWNFSL 600
  601 YKIYKFKVFK NKIELDFLKN EKESIEFEGK KMVTEFN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..398] PSI-BLAST 48.522879 No description for 2qkwB was found.
    2 View Details [399..506] FFAS03 3.03 Soluble adenylyl cyclase CyaC from S. platensis in complex with Rp- ATPalphaS
    3 View Details [507..637] PSI-BLAST 50.30103 Crystal structure of a mutant form of the mycobacterial adenylyl cyclase Rv1625c


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle