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Protein Overview: ceh-24

General Information:
Name(s) found: ceh-24 / CE25006 [WormBase]
Description(s) found:
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  • WBGene00000447 locus:ceh-24 Homeobox protein ceh-24 status:Confirmed UniProt:Q9NLC2 protein_id:CAB60999.1 [WormBase]
  • gi|75024273|sp|Q9NLC2.1|HM24_CAEEL RecName: Full=Homeobox protein ceh-24 [NCBI NR]
  • gi|71995902|ref|NP_506419.3| Homeobox family member (ceh-24) [Caenorhabditis elegans] [NCBI NR]
  • gi|6434296|emb|CAB60999.1| C. elegans protein F55B12.1, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • Homeobox protein ceh-24 OS=Caenorhabditis elegans GN=ceh-24 PE=2 SV=1 [Swiss-Prot]
  • [wormpep67.fasta]
  • Hypothetical protein F55B12.1 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE25006 WBGene00000447 locus:ceh-24 homeobox protein (NK-2 subfamily) status:Confirmed SW:Q9NLC2 protein_id:CAB60999.1 [wormpep150.fasta]
  • 25006 WBGene00000447 locus:ceh-24 homeobox protein (NK-2 subfamily) status:Partially_confirmed TR:Q9NLC2 protein_id:CAB60999.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • CE25006 WBGene00000447 locus:ceh-24 homeobox protein (NK-2 subfamily) status:Partially_confirmed TR:Q9NLC2 protein_id:CAB60999.1 [wormpep132.fasta]
  • 25006 WBGene00000447 locus:ceh-24 homeobox protein (NK-2 subfamily) status:Confirmed SW:Q9NLC2 protein_id:CAB60999.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE25006 WBGene00000447 locus:ceh-24 homeobox protein (NK-2 subfamily) status:Confirmed TR:Q9NLC2 protein_id:CAB60999.1 [WormBase_C-elegans_na_01-20-2005_combined_reversed.fasta]
  • locus:ceh-24 homeobox protein (NK-2 subfamily) status:Partially_confirmed TR:Q9NLC2 protein_id:CAB60999.1 [wormpep115.fasta.reversed]
  • CE25006 locus:ceh-24 homeobox protein (NK-2 subfamily) status:Predicted TR:Q9NLC2 protein_id:CAB60999.1 [wormpep80.hongbin]
  • CE25006 WBGene00000447 locus:ceh-24 homeobox protein (NK-2 subfamily) status:Confirmed UniProt:Q9NLC2 protein_id:CAB60999.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE25006 WBGene00000447 locus:ceh-24 homeobox protein (NK-2 subfamily) status:Confirmed UniProt:Q9NLC2 protein_id:CAB60999.1| [wormORF-contam.fasta]
  • Homeobox protein ceh-24 [nr-271106-contam.fasta]
  • C.Elegans Homeobox family member (ceh-24) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE25006 WBGene00000447 locus:ceh-24 status:Confirmed UniProt:Q9NLC2 protein_id:CAB60999.1 Homeobox protein ceh-24 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 299 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: negative regulation of multicellular organism growth [IMPLink to PubMed article]
    locomotion [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKETPSPV LDVKKEKNEE TGIDEEKSSE DDCSKRSKVK SNPSKFSVNS ILSPLESLVR  60
   61 VQQQLLKMAA SKSGTPGTNA GVPGAFPYGP GRLPGNYFAG PFPGYSGAQP NWYNGNDPRF 120
  121 AAAAALLPCS IDPVRSAINH QFSMSSMSQR RKRRVLFSQA QVYELERRFK QAKYLTAPER 180
  181 EQLANSIRLT PTQVKIWFQN HRYKCKRQEK EKAMSGLGHS EDGSSPPPDN DDDDDKYSIE 240
  241 MDDKDDEEEE ESEKPVLKPS GVFGLPYPPN AAAAAAAAAA AFNFPFAAQG PNPAYYMRW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] PSI-BLAST 8.522879 Pax-6
    2 View Details [80..149] deduced N/A No confident structure predictions are available.
    3 View Details [150..217] PSI-BLAST 16.045757 THYROID TRANSCRIPTION FACTOR 1 HOMEODOMAIN (RATTUS NORVEGICUS)
    4 View Details [218..299] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  1.62959077995642 bayes_pls_golite062009
  • binding
    		•  1.48969201384255 bayes_pls_golite062009
  • DNA binding
    		•  1.2137926921894 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.02805703044131 bayes_pls_golite062009
  • transcription factor activity
    		•  0.89626527070971 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.25215835583853 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.10684552272643 bayes_pls_golite062009
  • protein binding
    		•  0.012115247005138 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  1.62959077995642 bayes_pls_golite062009
  • binding
    		•  1.48969201384255 bayes_pls_golite062009
  • DNA binding
    		•  1.2137926921894 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.02805703044131 bayes_pls_golite062009
  • transcription factor activity
    		•  0.89626527070971 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.25215835583853 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.10684552272643 bayes_pls_golite062009
  • protein binding
    		•  0.012115247005138 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.52

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle