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View Structure Prediction Details

Protein: ceh-24
Organism: Caenorhabditis elegans
Length: 299 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ceh-24.

Description E-value Query
Range
Subject
Range
gi|2696969 - gi|2696969|dbj|BAA24022.1| PAX6 LS [Cynops pyrrhogaster]
161.0 [0..2] [287..105]

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Predicted Domain #1
Region A:
Residues: [1-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKETPSPV LDVKKEKNEE TGIDEEKSSE DDCSKRSKVK SNPSKFSVNS ILSPLESLVR  60
   61 VQQQLLKMAA SKSGTPGTN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.522879
Match: 6paxA
Description: Pax-6
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 1.62959077995642 bayes_pls_golite062009
binding 1.48969201384255 bayes_pls_golite062009
DNA binding 1.2137926921894 bayes_pls_golite062009
nucleic acid binding 1.02805703044131 bayes_pls_golite062009
transcription factor activity 0.89626527070971 bayes_pls_golite062009
transcription repressor activity 0.25215835583853 bayes_pls_golite062009
sequence-specific DNA binding 0.10684552272643 bayes_pls_golite062009
protein binding 0.012115247005138 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [80-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGVPGAFPYG PGRLPGNYFA GPFPGYSGAQ PNWYNGNDPR FAAAAALLPC SIDPVRSAIN  60
   61 HQFSMSSMSQ 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [150-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RRKRRVLFSQ AQVYELERRF KQAKYLTAPE REQLANSIRL TPTQVKIWFQ NHRYKCKRQE  60
   61 KEKAMSGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.045757
Match: 1fttA
Description: THYROID TRANSCRIPTION FACTOR 1 HOMEODOMAIN (RATTUS NORVEGICUS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 1.62959077995642 bayes_pls_golite062009
binding 1.48969201384255 bayes_pls_golite062009
DNA binding 1.2137926921894 bayes_pls_golite062009
nucleic acid binding 1.02805703044131 bayes_pls_golite062009
transcription factor activity 0.89626527070971 bayes_pls_golite062009
transcription repressor activity 0.25215835583853 bayes_pls_golite062009
sequence-specific DNA binding 0.10684552272643 bayes_pls_golite062009
protein binding 0.012115247005138 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [218-299]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHSEDGSSPP PDNDDDDDKY SIEMDDKDDE EEEESEKPVL KPSGVFGLPY PPNAAAAAAA  60
   61 AAAAFNFPFA AQGPNPAYYM RW

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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