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Protein Overview: lin-28

General Information:
Name(s) found: lin-28 / CE24879 [WormBase]
Description(s) found:
Found 24 descriptions.
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  • WBGene00003014 locus:lin-28 Protein lin-28 status:Confirmed UniProt:P92186 protein_id:CAB61008.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 227 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [IDALink to PubMed article]
    cytoplasm [IEALink to PubMed article]
    Biological Process: regulation of development, heterochronic [IMPLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    oviposition [IMPLink to PubMed article]
    response to stress [IEALink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    DNA binding [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTVVSEGRN DGNNRYSPQD EVEDRLPDVV DNRLTENMRV PSFERLPSPT PRYFGSCKWF  60
   61 NVSKGYGFVI DDITGEDLFV HQSNLNMQGF RSLDEGERVS YYIQERSNGK GREAYAVSGE 120
  121 VEGQGLKGSR IHPLGRKKAV SLRCFRCGKF ATHKAKSCPN VKTDAKVCYT CGSEEHVSSI 180
  181 CPERRRKHRP EQVAAEEAEA ARMAAEKSSP TTSDDDIREK NSNSSDE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..126] PSI-BLAST 13.09691 Major cold shock protein
    2 View Details [127..227] PSI-BLAST 9.69897 NUCLEOCAPSID ZINC FINGERS DETECTED IN RETROVIRUSES: EXAFS STUDIES ON INTACT VIRUSES AND THE SOLUTION-STATE STRUCTURE OF THE NUCLEOCAPSID PROTEIN FROM HIV-1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.99628257193121 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.55535848952041 bayes_pls_golite062009
  • DNA binding
    		•  0.969246048450989 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.890081297694346 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.75578703467841 bayes_pls_golite062009
  • protein binding
    		•  0.0528188351789111 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle