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Protein Overview: lec-3

General Information:
Name(s) found: lec-3 / CE24743 [WormBase]
Description(s) found:
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  • WBGene00002266 locus:lec-3 32 kDa beta-galactoside-binding lectin lec-3 status:Confirmed UniProt:Q09581 protein_id:CAA88570.2 [WormBase]
  • gi|9857645|dbj|BAB11969.1| galectin LEC-3 [Caenorhabditis elegans] [NCBI NR]
  • pir||T28073 hypothetical protein ZK892.1 - Caenorhabditis elegans [NCBI NR]
  • gi|5824902|emb|CAA88570.2| C. elegans protein ZK892.1a, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|18275592|sp|Q09581.3|LEC3_CAEEL RecName: Full=32 kDa beta-galactoside-binding lectin lec-3; AltName: Full=32 kDa GBP [NCBI NR]
  • gi|17535117|ref|NP_496159.1| gaLECtin family member (lec-3) [Caenorhabditis elegans] [NCBI NR]
  • 32 kDa beta-galactoside-binding lectin lec-3 OS=Caenorhabditis elegans GN=lec-3 PE=2 SV=3 [Swiss-Prot]
  • [wormpep67.fasta]
  • CE24743 WBGene00002266 locus:lec-3 galactoside-binding lectin status:Confirmed SW:Q09581 protein_id:CAA88570.2 [wormpep150.fasta]
  • 24743 WBGene00002266 locus:lec-3 galactoside-binding lectin status:Confirmed SW:Q09581 protein_id:CAA88570.2 [wormpep130-phg-ecoli-orf-rand.fasta]
  • galectin (33.6 kD) (lec-3) [Caenorhabditis elegans]gi|5824902|emb|CAA88570.2| Hypothetical protein ZK892.1a [Caenorhabditis elegans]gi|7511387|pir||T28073 hypothetical protein ZK892.1 - Caenorhabditis elegansgi|18275592|sp|Q09581|LEC3_CAEEL 32 kDa beta [nrdb_11152004_Chlamydomonas]
  • locus:lec-3 galactoside-binding lectin status:Confirmed SW:Q09581 protein_id:CAA88570.2 [wormpep115.fasta.reversed]
  • CE24743 galactoside-binding lectin status:Confirmed SW:Q09581 protein_id:CAA88570.2 [wormpep80.hongbin]
  • CE24743 WBGene00002266 locus:lec-3 galactoside-binding lectin status:Confirmed UniProt:Q09581 protein_id:CAA88570.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE24743 WBGene00002266 locus:lec-3 galactoside-binding lectin status:Confirmed UniProt:Q09581 protein_id:CAA88570.2| [wormORF-contam.fasta]
  • 32 kDa beta-galactoside-binding lectin lec-3 (32 kDa GBP) [nr-271106-contam.fasta]
  • galectin LEC-3 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • gaLECtin family member (lec-3) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein ZK892.1a [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE24743 WBGene00002266 locus:lec-3 status:Confirmed UniProt:Q09581 protein_id:CAA88570.2 32 kDa beta-galactoside-binding lectin lec-3 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 297 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: sugar binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPKSFNIP YRSKLTERIE PGQTLIIRGK TIDESKRFNI NLHKDSPDFS GNDVPLHLSI  60
   61 RFDEGKIVYN AYTKGTWGKE ERAKNPIKKG DDFDIRIRAH DSKFQVSINH KEVKNFEHRI 120
  121 PLNSVSHLSI DGDVVLNHVQ WGGKYYPVPY ESGIAADGLV PGKTLVVYGT PEKKAKKFNI 180
  181 NLLKKNGDIA LHFNPRFDEK ANGFMCAKPT PGSVVRNSLV NGEWGNEERE GKNPFERLTA 240
  241 FDLEIRNEEF AFQIFVNGER FASYAHRVDP HDIAGLQIQG DIELTGIQVV NNQPAQE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..155] PSI-BLAST 42.69897 No description for 2dycA was found.
    2 View Details [156..297] PSI-BLAST 35.69897 X-RAY CRYSTAL STRUCTURE OF HUMAN GALECTIN-1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • sugar binding
    		•  3.34064405064299 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.70103238455595 bayes_pls_golite062009
  • polysaccharide binding
    		•  2.35851723238763 bayes_pls_golite062009
  • monosaccharide binding
    		•  2.09529521879228 bayes_pls_golite062009
  • fibronectin binding
    		•  1.99928468833374 bayes_pls_golite062009
  • carbohydrate binding
    		•  1.90829797790335 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  1.88496254097559 bayes_pls_golite062009
  • protein binding
    		•  1.80794638640093 bayes_pls_golite062009
  • binding
    		•  1.76108014916376 bayes_pls_golite062009
  • heparin binding
    		•  1.60966215355794 bayes_pls_golite062009
  • extracellular matrix binding
    		•  1.41229380365824 bayes_pls_golite062009
  • signal transducer activity
    		•  1.24423621131253 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.24423621131253 bayes_pls_golite062009
  • galactoside binding
    		•  1.08479183125487 bayes_pls_golite062009
  • pattern binding
    		•  0.969915174528009 bayes_pls_golite062009
  • receptor binding
    		•  0.9012250808046 bayes_pls_golite062009
  • fibroblast growth factor 2 binding
    		•  0.79803357365664 bayes_pls_golite062009
  • fibrinogen binding
    		•  0.79803357365664 bayes_pls_golite062009
  • receptor activity
    		•  0.376562682962271 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.213382263378401 bayes_pls_golite062009
  • growth factor activity
    		•  0.119475011376319 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle