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View Structure Prediction Details

Protein: lec-3
Organism: Caenorhabditis elegans
Length: 297 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lec-3.

Description E-value Query
Range
Subject
Range
lec-3 - galactoside-binding lectin status:Confirmed UniProt:Q95ZI4 protein_id:CAC42392.1
307.0 [0..1] [297..1]

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Predicted Domain #1
Region A:
Residues: [1-155]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEPKSFNIP YRSKLTERIE PGQTLIIRGK TIDESKRFNI NLHKDSPDFS GNDVPLHLSI  60
   61 RFDEGKIVYN AYTKGTWGKE ERAKNPIKKG DDFDIRIRAH DSKFQVSINH KEVKNFEHRI 120
  121 PLNSVSHLSI DGDVVLNHVQ WGGKYYPVPY ESGIA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.69897
Match: 2dycA
Description: No description for 2dycA was found.

Predicted Domain #2
Region A:
Residues: [156-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADGLVPGKTL VVYGTPEKKA KKFNINLLKK NGDIALHFNP RFDEKANGFM CAKPTPGSVV  60
   61 RNSLVNGEWG NEEREGKNPF ERLTAFDLEI RNEEFAFQIF VNGERFASYA HRVDPHDIAG 120
  121 LQIQGDIELT GIQVVNNQPA QE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.69897
Match: 1gzwA
Description: X-RAY CRYSTAL STRUCTURE OF HUMAN GALECTIN-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sugar binding 3.34064405064299 bayes_pls_golite062009
glycosaminoglycan binding 2.70103238455595 bayes_pls_golite062009
polysaccharide binding 2.35851723238763 bayes_pls_golite062009
monosaccharide binding 2.09529521879228 bayes_pls_golite062009
fibronectin binding 1.99928468833374 bayes_pls_golite062009
carbohydrate binding 1.90829797790335 bayes_pls_golite062009
extracellular matrix structural constituent 1.88496254097559 bayes_pls_golite062009
protein binding 1.80794638640093 bayes_pls_golite062009
binding 1.76108014916376 bayes_pls_golite062009
heparin binding 1.60966215355794 bayes_pls_golite062009
extracellular matrix binding 1.41229380365824 bayes_pls_golite062009
signal transducer activity 1.24423621131253 bayes_pls_golite062009
molecular transducer activity 1.24423621131253 bayes_pls_golite062009
galactoside binding 1.08479183125487 bayes_pls_golite062009
pattern binding 0.969915174528009 bayes_pls_golite062009
receptor binding 0.9012250808046 bayes_pls_golite062009
fibroblast growth factor 2 binding 0.79803357365664 bayes_pls_golite062009
fibrinogen binding 0.79803357365664 bayes_pls_golite062009
receptor activity 0.376562682962271 bayes_pls_golite062009
transmembrane receptor activity 0.213382263378401 bayes_pls_golite062009
growth factor activity 0.119475011376319 bayes_pls_golite062009

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