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Protein Overview: efl-2

General Information:
Name(s) found: efl-2 / CE24382 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00001162 locus:efl-2 status:Partially_confirmed UniProt:Q9U289 protein_id:CAB60421.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 412 amino acids

    Gene Ontology:
    Cellular Component: transcription factor complex [IEALink to PubMed article]
    Biological Process: regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPSSIDLGS IPGGSEQQQH EDGAAAAAGS PKEVFRSQQS LGLITQRFMS LRQRNEVLNL  60
   61 NEVAKELNIS KRRVYDVINV LEGLGYVEKV EKNNIRWIGD NNNSEEQNAL EARVEMLRQQ 120
  121 EKLLELMIRD AQAIIELHFE DPIERPYNYV SKEDIRKTAE PNTKSIIVKS ELDTSSSFEI 180
  181 QVTDPSTSGS HDMIVRNKNG VKSHALLFTN DPPEYGDEED EDDVKKLSSQ KRFETSEALR 240
  241 VTLAEMLTDP TTISSSPKHI KLEEPEEIDT EDLETFAPPE FSENKWSQKI GGGLAILWAW 300
  301 LALMPRPQNG NFFSAKFFKF FPETVARKTF VLPPSTSASQ SNAPYLPETP GRGLFFSPFK 360
  361 SLIDPCILPS FSDDLTSGYI NITTPSRATG AGAGASGQED EEPVSVMDFF SD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..102] PSI-BLAST 25.0 Cell cycle transcription factor E2F-4
    2 View Details [103..317] PSI-BLAST 24.69897 Structure of the Rb C-terminal domain bound to an E2F1-DP1 heterodimer
    3 View Details [318..412] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  2.04426015975991 bayes_pls_golite062009
  • binding
    		•  1.99063774159045 bayes_pls_golite062009
  • DNA binding
    		•  1.63968725174405 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.51035375793093 bayes_pls_golite062009
  • transcription factor activity
    		•  1.16072080355661 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.55739080981393 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.17466804820317 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle