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Protein Overview: ccf-1

General Information:
Name(s) found: ccf-1 / CE22588 [WormBase]
Description(s) found:
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  • WBGene00000369 locus:ccf-1 CCR4-NOT transcription complex subunit 7 status:Confirmed UniProt:Q17345 protein_id:CAB60501.1 [WormBase]
  • gi|726134|gb|AAA87454.1| cCAF1 protein [Caenorhabditis elegans] [NCBI NR]
  • gi|6425388|emb|CAB60501.1| C. elegans protein Y56A3A.20, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • gi|3219781|sp|Q17345.1|CNOT7_CAEEL RecName: Full=CCR4-NOT transcription complex subunit 7; AltName: Full=CCR4-associated factor 1; Short=CAF1 [NCBI NR]
  • gi|17556296|ref|NP_499553.1| yeast CCR4 Associated Factor family member (ccf-1) [Caenorhabditis elegans] [NCBI NR]
  • CCR4-NOT transcription complex subunit 7 OS=Caenorhabditis elegans GN=ccf-1 PE=2 SV=1 [Swiss-Prot]
  • (Q17345) CCR4-NOT transcription complex subunit 7 (CCR4-associated factor 1) (CAF1) [Swiss-Prot]
  • [wormpep67.fasta]
  • CE22588 WBGene00000369 locus:ccf-1 status:Confirmed SW:Q17345 protein_id:CAB60501.1 [wormpep150.fasta]
  • 22588 WBGene00000369 locus:ccf-1 status:Confirmed SW:Q17345 protein_id:CAB60501.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • yeast CCR4-associated Factor, CAF1 family ribonuclease, CCR4-NOT transcription complex subunit (33.8 kD) (ccf-1) [Caenorhabditis elegans]gi|6425388|emb|CAB60501.1| Hypothetical protein Y56A3A.20 [Caenorhabditis elegans]gi|726134|gb|AAA87454.1| cCAF1 pro [nrdb_11152004_Chlamydomonas]
  • locus:ccf-1 status:Confirmed SW:Q17345 protein_id:CAB60501.1 [wormpep115.fasta.reversed]
  • CE22588 status:Confirmed SW:Q17345 protein_id:CAB60501.1 [wormpep80.hongbin]
  • CE22588 WBGene00000369 locus:ccf-1 status:Confirmed UniProt:Q17345 protein_id:CAB60501.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE22588 WBGene00000369 locus:ccf-1 status:Confirmed UniProt:Q17345 protein_id:CAB60501.1| [wormORF-contam.fasta]
  • cCAF1 protein [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein Y56A3A.20 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • yeast CCR4 Associated Factor family member (ccf-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CCR4-NOT transcription complex subunit 7 (CCR4-associated factor 1) (CAF1) [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE22588 WBGene00000369 locus:ccf-1 status:Confirmed UniProt:Q17345 protein_id:CAB60501.1 CCR4-NOT transcription complex subunit 7 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 310 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: hermaphrodite genitalia development [IMPLink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    germline cell cycle switching, mitotic to meiotic cell cycle [IMPLink to PubMed article]
    reproduction [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSSSGGAG GAGGASGAPE VKIHNVYMSN VEEEFARIRG FVEDYPYVAM DTEFPGVVAT  60
   61 PLGTFRSKED FNYQQVFCNV NMLKLIQVGF AMVNDKGELP PTGDVWQFNF NFSFAEDMFS 120
  121 HESVEMLRQA GIDFTLLQNN GIPTAVFGEL LTTSGLITDP RITWLTFSSG YDFGYLLKSI 180
  181 TLGDLPKEES TFFMCHKTLF PTSFDIKILL RTPNCASAKL KGGLQEVADQ LDVKRQGVRH 240
  241 QAGSDALLTA ATFFKIKKQF FGDNWNQIAP LICGHMFGLG SSLSLFHSSG STSRLGDETP 300
  301 QGLIGVPQQA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..310] PSI-BLAST 98.0 No description for 2d5rA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease activity
    		•  5.30591758406946 bayes_pls_golite062009
  • exoribonuclease activity
    		•  3.71639182685131 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  3.59362615133405 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  3.1992647486402 bayes_pls_golite062009
  • nuclease activity
    		•  3.11657409772275 bayes_pls_golite062009
  • ribonuclease H activity
    		•  2.91966688044755 bayes_pls_golite062009
  • hydrolase activity
    		•  2.78602644579272 bayes_pls_golite062009
    		• 2.73492915653996 bayes_pls_golite062009
  • endonuclease activity
    		•  2.63074055051349 bayes_pls_golite062009
  • endoribonuclease activity
    		•  2.59247838057313 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.57498413015114 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.20855917457806 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.14285769817394 bayes_pls_golite062009
  • exonuclease activity
    		•  1.87925169250843 bayes_pls_golite062009
  • DNA binding
    		•  1.86594005896134 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  1.44123900197846 bayes_pls_golite062009
  • RNA binding
    		•  1.43996903907704 bayes_pls_golite062009
  • transcription activator activity
    		•  1.43417601839369 bayes_pls_golite062009
  • binding
    		•  1.35497934205068 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.32513822925426 bayes_pls_golite062009
  • catalytic activity
    		•  1.25233849524628 bayes_pls_golite062009
  • transcription factor activity
    		•  1.17659544650821 bayes_pls_golite062009
  • protein binding
    		•  1.08578027658199 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.71760273606768 bayes_pls_golite062009
  • endoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.708753843279937 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.615788727884275 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.598360955770972 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  0.24906263529692 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.09423425042945 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.0189279348688405 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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