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Protein Overview: CE22292

General Information:
Name(s) found: CE22292 [WormBase]
Description(s) found:
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  • WBGene00021747 status:Partially_confirmed UniProt:Q965R0 protein_id:CCD72440.1 [WormBase]
  • gi|17565904|ref|NP_503357.1| hypothetical protein Y50D4C.2 [Caenorhabditis elegans] [NCBI NR]
  • gi|14574377|gb|AAK68507.1|AC025722_2 Hypothetical protein Y50D4C.2 [Caenorhabditis elegans] [NCBI NR]
  • [wormpep67.fasta]
  • CE22292 WBGene00021747 status:Partially_confirmed TR:Q965R0 protein_id:AAK68507.1 [wormpep150.fasta]
  • 22292 WBGene00021747 status:Partially_confirmed TR:Q965R0 protein_id:AAK68507.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • alcohol dehydrogenase class 3 (5B417) [Caenorhabditis elegans]gi|14574377|gb|AAK68507.1| Hypothetical protein Y50D4C.2 [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • status:Partially_confirmed TR:Q965R0 protein_id:AAK68507.1 [wormpep115.fasta.reversed]
  • CE22292 status:Predicted TR:Q965R0 protein_id:AAK68507.1 [wormpep80.hongbin]
  • CE22292 WBGene00021747 status:Partially_confirmed UniProt:Q965R0_CAEEL protein_id:AAK68507.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE22292 WBGene00021747 status:Partially_confirmed UniProt:Q965R0_CAEEL protein_id:AAK68507.1| [wormORF-contam.fasta]
  • Y50D4C.2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein Y50D4C.2 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE22292 WBGene00021747 status:Partially_confirmed UniProt:Q965R0 protein_id:AAK68507.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • CE22292 WBGene00021747 status:Partially_confirmed UniProt:Q965R0 protein_id:CCD72440.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
    • Organism: Caenorhabditis elegans
    Length: 554 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: threonine catabolic process [IEALink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    oxidoreductase activity [IEALink to PubMed article]
    L-threonine 3-dehydrogenase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSFLTNTLF SLKLNLHHFN FQMTSVRAQI HQQLYKTKTI APALTITNAV TGGFDELGEF  60
   61 GLDDVENLMI SNSRLTTFTN FPFMPKLKTL DVSCNNFHGV IDMSILARNA PRLKVLILDD 120
  121 NQIHIGSISS LNGVRKLANL STTLTGDASP EHCDRNEKII ARVLPKLKIL NDEVVKRDEI 180
  181 IPARPPSPGA QKLHSRLKRS KWLHRKPTKF ALKYILYTSV CHTDAYTLDG HDPEGLFPVV 240
  241 LGHEGSGIVE SVGKGVTGFA PGDHVVPLYV PQCKECEYCK NPKTNMCQKI RVSQGDGFMP 300
  301 DGTSRFTCNG KQLFHFMGCS TFSEYTVVAD ISLCKVNPQA PLEKVSLLGC GISTGYGAVL 360
  361 NTCKVEEGST VAVWGLGAVG LAVIMGAKAA GAKKIVGIDL IESKFEKAKM FGATECINPK 420
  421 SVELPEGKSF QSWLVEQFDG GFDYTFECIG NVHTMRQALE AAHKGWGVSC IIGVAGAGQE 480
  481 IATRPFQLVT GRTWKGTAFG GWKSVESVPR LVDDYMNKKL LIDEFITHRC NIDDINAAFD 540
  541 VLRKGEGLRS RLTF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..213] PSI-BLAST 24.0 No description for 2v70A was found.
    2 View Details [214..554] PSI-BLAST 85.522879 Alcohol dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • ethanol binding
    		•  4.47659026306883 bayes_pls_golite062009
  • NAD or NADH binding
    		•  4.35058438816264 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  4.1750549780559 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • alcohol binding
    		•  2.97042200128883 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  2.94416173750168 bayes_pls_golite062009
  • retinol binding
    		•  2.89007863838685 bayes_pls_golite062009
  • all-trans retinal binding
    		•  2.84803957533249 bayes_pls_golite062009
  • S-(hydroxymethyl)glutathione dehydrogenase activity
    		•  2.58673703881996 bayes_pls_golite062009
  • hydroxymethylfurfural reductase (NADH) activity
    		•  2.2999175117758 bayes_pls_golite062009
  • hydroxymethylfurfural reductase activity
    		•  2.2999175117758 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  2.26153457113968 bayes_pls_golite062009
  • NADPH:quinone reductase activity
    		•  2.16668841986245 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  2.03039843216597 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  1.29842732066898 bayes_pls_golite062009
  • chaperone binding
    		•  1.19079350615542 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  1.01627645289834 bayes_pls_golite062009
  • binding
    		•  0.784517759335365 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  0.62461633437589 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.527946013169731 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.484089941059577 bayes_pls_golite062009
  • kinase activity
    		•  0.461063813999598 bayes_pls_golite062009
  • hydroxymethylfurfural reductase (NADPH) activity
    		•  0.382131941157781 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.375415252607746 bayes_pls_golite062009
  • coenzyme binding
    		•  0.35922330382799 bayes_pls_golite062009
  • protein kinase activity
    		•  0.339420053437627 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.274019118261823 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  0.233238483713519 bayes_pls_golite062009
  • methylenetetrahydrofolate dehydrogenase activity
    		•  0.169301675015808 bayes_pls_golite062009
  • DNA binding
    		•  0.164288600669795 bayes_pls_golite062009
  • methenyltetrahydrofolate cyclohydrolase activity
    		•  0.162625185692811 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  0.0962368786590111 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.72

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle