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Protein Overview: CE21988

General Information:
Name(s) found: CE21988 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00012904 locus:tiar-2 status:Partially_confirmed UniProt:Q9U2F5 protein_id:CAB60356.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 434 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: mRNA processing [IEALink to PubMed article]
    Molecular Function: nucleic acid binding [IEALink to PubMed article]
    RNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATSFYTGGG EDGDGFNPRV HARIAEREGF QLASGSEDPR TLFVANLDPA ITDEFLATLF  60
   61 NQIGAVMKAK IIFEGLNDPY AFVEFSDHNQ ATLALQSHNG RELLEKEMHV TWAFEPREPG 120
  121 ENRSKPETSR HFHVFVGDLC SEIDSTKLRE AFVKFGEVSE AKIIRDNNTN KGKGYGFVSY 180
  181 PRREDAERAI DEMNGAWLGR RTIRTNWATR KPDEDGERGG DRGDRRGGGG GGRDRYHNQS 240
  241 EKTYDEIFNQ AAADNTSVYV GNIANLGEDE IRRAFDRFGP INEVRTFKIQ GYAFVKFETK 300
  301 ESAARAIVQM NNADIGGQIV RCSWGKSGDS GKPSERGSGG GGGSGNYGYG YGNSGGGGGS 360
  361 GGPGNSQFSN FNQRPPPSGN GGSGGGSGGQ NNQYWQYYSQ YYNNPHLMQQ WNNYWQKDGP 420
  421 PPPPAAAASS TGGN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..211] PSI-BLAST 47.0 Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
    2 View Details [212..341] FFAS03 4.53 No description for 2bz2A was found.
    3 View Details [342..434] PSI-BLAST 3.09691 Sec24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  5.15097136329571 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • mRNA binding
    		•  4.05281507540116 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
    		• 2.60920363363072 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.18211199677674 bayes_pls_golite062009
  • DNA binding
    		•  1.98418556946403 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  1.46469774223879 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  1.36691748240059 bayes_pls_golite062009
  • protein binding
    		•  1.12215421354121 bayes_pls_golite062009
  • transcription factor activity
    		•  1.07843408116687 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.824614388276642 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
    2
    Term Confidence Notes
  • RNA binding
    		•  4.74219150342477 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.65259034341669 bayes_pls_golite062009
  • mRNA binding
    		•  3.63162433534903 bayes_pls_golite062009
  • binding
    		•  3.48033873254013 bayes_pls_golite062009
    		• 2.38034004712143 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.2045206027152 bayes_pls_golite062009
  • DNA binding
    		•  1.99030664201171 bayes_pls_golite062009
  • transcription factor activity
    		•  1.09958329302628 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  1.08300488237934 bayes_pls_golite062009
  • protein binding
    		•  1.05805521997665 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.960399311787502 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.462558743683805 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.327072171076297 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle