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Protein Overview: pptr-2

General Information:
Name(s) found: pptr-2 / CE20505 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00007554 locus:pptr-2 status:Confirmed UniProt:Q9U3Q1 protein_id:CAA98423.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 561 amino acids

    Gene Ontology:
    Cellular Component: protein phosphatase type 2A complex [IEALink to PubMed article]
    Biological Process: signal transduction [IEALink to PubMed article]
    nematode larval development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    Molecular Function: protein phosphatase type 2A regulator activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIPADAPPPT NIGRTNTYGG DLISGPVIPR RERRQSSSMF NISQNRELQR LPAIKDADPS  60
   61 ERETLFIQKL RQCCVVFDFA NDALSDLKFK EVKRAALNEL VDHVSGAPKG SLSDAVYPEA 120
  121 IGMFSTNLFR PLSPPTNPIG AEFDPDEDEP TLEAAWPHLQ LVYEFFLRFL ECPDFQSQVA 180
  181 KRYIDQNFIL RLLMIMDSED PRERDFLKTT LHRIYGKFLG HRAYIRKQIN NIFYSFIYET 240
  241 ERHNGIAELL EILGSIINGF ALPLKEEHKT FLLRVLLPLH KVKSLSVYHP QLAYCVVQFI 300
  301 EKDSSLTEPV ISGMLRFWPK QHSPKEVMFL NELEEVLDVI EPNEFQKIMT PLFSQIARCV 360
  361 SSPHFQVAER ALYYWNNEYV MSLVADNARV IIPIMFPVLF KNSKSHWNKT IHGLIYNALK 420
  421 MFMEMNQKLF DECSQAYQKD RVQEKTLNEE KERIWNNIEK QAMGNPQYVE VKALFARFNP 480
  481 DEIISSRQQN GVDENMKTST VLSKDEILKN AVGVSSMKND MDFGPNHKQS DFPPDEQTTR 540
  541 ALGEYKRHDP FLKKVTSTDE Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..473] PSI-BLAST 1000.0 No description for 2nppB was found.
    2 View Details [474..561] MSA 1.033985 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  3.0667965351474 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  2.90442709223348 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  2.43818477885422 bayes_pls_golite062009
  • protein phosphatase type 2A regulator activity
    		•  2.4262941420561 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.13472456858224 bayes_pls_golite062009
  • phosphatase regulator activity
    		•  1.88919819318597 bayes_pls_golite062009
  • protein phosphatase regulator activity
    		•  1.7842476658781 bayes_pls_golite062009
  • protein binding
    		•  1.73688475473996 bayes_pls_golite062009
  • phosphatase activity
    		•  1.47453833246612 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  1.24670233688276 bayes_pls_golite062009
  • myosin phosphatase activity
    		•  1.2020405346133 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.13208464017585 bayes_pls_golite062009
  • hydrolase activity
    		•  0.42501390959416 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.385452858197632 bayes_pls_golite062009
  • DNA binding
    		•  0.309260217284589 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle